Protein Alignment GABA-B-R3 and smog

DIOPT Version :9

• Sequence 1: NP_001245826.1
• Gene: GABA-B-R3 / 33248
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: NP_001245881.1
• Gene: smog / 33690
• FlyBaseID: FBgn0051660
• Length: 951
• Species: Drosophila melanogaster
• Alignment Length: 1167
• Identity: 220/1167 - (18%)
• Similarity: 369/1167 - (31%)
• Gaps: 391/1167 - (33%)

  Fly    27 AWATSAAAAMESSAELQALGYEAIRPGAASISTSSPSSS--------PPGESAST---------- 73
            |.|.|||||..|         |:.|......|:||.|||        .|..|:||
  Fly    77 ATAASAAAATLS---------ESTRCNIIISSSSSSSSSTKSSKNIREPSSSSSTQLNTLYSLLV 132

  Fly    74 ------VTAGGTPIPPRSDWKYKRTKVKRRQQRLNSHSNLPGSTNA----SHAHHLLNLPPRQRY 128
                  .||..:|.|..|...:.|...:.........::||.|:::    .|.:|||:......:
  Fly   133 LLIVGLATATASPSPSPSHAPFGRESRRDALLAYYKRAHLPQSSSSGISLGHKYHLLHDANGLDF 197

  Fly   129 LKVNQVFESERRMSPAEMQRNHGKIVLLGLFELSTSRGPRPD------GLSELGAATMAVEHINR 187
            .::.....|...:|.||.            |.| ..|...|.      |::.|..||.|.
  Fly   198 DELTPTASSVSALSRAER------------FRL-RKRSATPTTPATAAGVTSLDVATAAA----- 244

  Fly   188 KRLLPGYTLELVTNDTQCDPGVGVDRFFHAIYTQPSTRMVMLLGSACS-EVTESLAKVVPYWNIV 251
                      ..|:....|.|.|         .:|..:        |. :|.|:|.. .|:::..
  Fly   245 ----------AATDAAAKDAGSG---------KKPEEK--------CEPKVLETLPD-EPFYDYT 281

  Fly   252 QVSFGSTSPALSDRREFPYFYRTVAPDSS-----HNPARIAFIRKFGWGTVTTFSQNEEVHSLAV 311
            .:       |....|:|..|.....|:::     ..|.|....|:.  ..:.:::.||:
  Fly   282 DI-------AEDAARQFIEFLSGKFPNANTPIAIDEPTRAEVSRRA--NGIASYALNED------ 331

  Fly   312 NNLVTELEAANISCAATITFAATDFKEQLLL-LRETDTRIIIGSFSQELAPQILCEAYRLRMFGA 375
            :||:     |....|.:|......|::.:.: ..:...:..:||:.:||              ||
  Fly   332 DNLL-----AFAIAAPSIHTVVVKFRDNVTIPPDQVHNKAYLGSYWREL--------------GA 377

  Fly   376 DYAWIL---HESMGAP----------W-WPDQRTACSNHELQLAVENLIVVSTHNSIVGNNVSYS 426
              ||..   .:..|||          | || .|.:.|.|.:::.....|...       .:|...
  Fly   378 --AWNSTDGTQEWGAPFRDCNLLTRRWLWP-FRISFSEHRIKVVAAAFIAAD-------EDVCND 432

  Fly   427 GLNNHMFNSQLRKQSAQFHGQDGFGSGYGSRISIAATQSDSRRRRRRGVGGTSGGHLFPEAISQY 491
            ||                  ::.||                   ||.|....:...|..|.....
  Fly   433 GL------------------EEVFG-------------------RRHGCDRNTTFCLLTENKPAA 460

  Fly   492 APQTYDAVWAIALALRAAEEHWRRNEEQSKLDGFDYTRSDMAWEFLQQMGKLHFLGVSGPVSFSG 556
            ....|..:        ..|.::..|   |.|.||...|.:::      .|..::..:..|...:.
  Fly   461 TRDVYTCL--------CRESYYLPN---STLQGFRGDRVELS------EGYDNYSCIPCPGGCTN 508

  Fly   557 PDRVGTTAFYQIQRGLLEPVALYYPATDALDFRCPRCRPVKWHSGQVPIAKRVFKLRVATIAPLA 621
            .|..|....:|.:..|         ..||       |                .:|.||
  Fly   509 CDSNGVCLTFQEEEVL---------NVDA-------C----------------LRLLVA------ 535

  Fly   622 FYTIATLSSVGIALAIAFLAFNLHFRKLKAIKLSSPKLSNITAVGCIFVYATVILLGLDHSTLPS 686
               |...:.:...:.:..:.|..  ||.|||......:.....:|.:.:||:|.:    |....|
  Fly   536 ---IVLGACILCCIVLGVIVFRQ--RKCKAIASGMWTVLETILLGIVLLYASVAV----HFFPAS 591

  Fly   687 AEDSFATVCTARVYLLSAGFSLAFGSMFAKTYRVHRIFTRTGSVFKDKMLQDIQLILLVGGLLLV 751
            .|.     |....:|...||...:|::..|.|| |.:..||....: .:|:|:.|:..:|  .:|
  Fly   592 TER-----CLLEPWLRELGFITCYGAIILKLYR-HLVDFRTRKAHR-WVLRDVDLLKYLG--TMV 647

  Fly   752 DALLVTLWVVTDPMERHLHNLTLEISATDRSVVYQPQVEVCRSQHTQT-----WLSVLYAYKGLL 811
            .|::..:...|               |:...::...|:|..|...|.|     |..|....:.|:
  Fly   648 FAVICYMAAFT---------------ASSLDLLESAQLESLREADTNTCHPLKWELVTQTSEMLI 697

  Fly   812 LVVGVYMAWETRHVK---------IPALNDSQYIGVSVYSVVIT-----SAIVVVLANLISERVT 862
            |..|::::..:|:..         :.||.....:..|.|.:...     |...::||..|..::|
  Fly   698 LCFGLHLSIASRNANTQFRERQFLVTALTLEFLVSSSFYFLRFVYLPEMSPSAILLALFIRSQLT 762

  Fly   863 LAFITITALILTSTTATLCLLFIPKLHDIWARNDIIDPVIHSMGLKMECNTRRFVVDDRRELQYR 927
            .:|             .|.|:|:|||   |.::..:                       |.|.|.
  Fly   763 NSF-------------ALGLIFVPKL---WYQHKQV-----------------------RSLAYD 788

  Fly   928 VEVQNRVYKKEIQALDAEIRKLERLLESGLTTTSTTTSSSTSLLTGGGHL-----KP---ELTVT 984
            :.::..|        ||                ...||.......|||:.     .|   |||::
  Fly   789 LSIRLPV--------DA----------------FKGTSHDAGQRLGGGYAGLCLGDPDIGELTIS 829

  Fly   985 SGISQTPAASKNRTPSISGILPN-LLLSVLPPVIPRASWPSAEYMQIPMRRSVTFASQPQLEEAC 1048
            ....:...|...|..:...|:.| .|....|.:..|.....|.:.:..:::..:       ::..
  Fly   830 EMSPEDIRAELKRLYTQLEIMKNKTLRQDNPHISKRRGGRKAGHRRFSLQKKGS-------KDKA 887

  Fly  1049 LPAQDLINLRLAHQQATEAKTGLINRLRGIFSRT----TSSNKGSTASLADQKGLKAAFKSH 1106
            |.|:...|......:.|||:.          |||    ..|.:|.|.:.|:..|:..:..||
  Fly   888 LSAKHRSNKHHQDIEITEAEP----------SRTPEDSVCSAEGPTDTYAEISGVSHSMLSH 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_001245826.1	PBP1_GABAb_receptor	157..590	CDD:107361	79/459 (17%)
		ANF_receptor	174..568	CDD:279440	70/414 (17%)
		7tm_3	633..889	CDD:278433	58/274 (21%)
smog	NP_001245881.1	7tm_3	542..776	CDD:278433	59/279 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910