Protein Alignment GABA-B-R3 and Vom2r10

DIOPT Version :9

• Sequence 1: NP_001245826.1
• Gene: GABA-B-R3 / 33248
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: NP_001092939.1
• Gene: Vom2r10 / 292414
• RGDID: 1565464
• Length: 858
• Species: Rattus norvegicus
• Alignment Length: 909
• Identity: 172/909 - (18%)
• Similarity: 300/909 - (33%)
• Gaps: 270/909 - (29%)

  Fly   149 NHGKIVLLGLFELST----SRGPRP-------DGLSELG--------AATMAVEHIN-RKRLLPG 193
            :.|.||:...|.|.|    .:.|.|       |...:..        |...|:|.|| ...|||.
  Rat    38 HEGDIVIGAFFPLHTFYTGKKMPDPTLPYQYLDNYIQYNFRNYQYILALLFAIEEINGNPNLLPN 102

  Fly   194 YTLELVTNDTQCDPGVGVDRFFHAIYTQPSTRMVMLLGSACSEVTESL-AKVVPYWN-------- 249
            .:|             |.| |::..:|:..|.|     :|...:|..: .||:|.:|
  Rat   103 ISL-------------GFD-FYNVRFTEKETLM-----NAVIWLTAHVQRKVLPNYNCKKKKFSA 148

  Fly   250 ---------------------IVQVSFGSTSPALSDRREFPYFYRTVAPDSSHNPARIAFIRKFG 293
                                 ..|::||...|.|||..::...|:....|:|.:.|.::.:..|.
  Rat   149 ALTGTSWTTSAQIGTLLQLFKFPQITFGPYDPLLSDHGQYSSLYQMAPKDTSLSLAIVSLMVYFR 213

  Fly   294 WGTVTTFSQNEEVHSLAVNNLVTELEAANISCA------ATITFAATDFKEQLLLLRETDTRIII 352
            |..|.....::...:..:::...|:|...:..|      ||.|.....|.|.   :.||:..||.
  Rat   214 WSWVGLILPDDHKGNKILSDYREEMERQRVCIAFVKMIPATWTSYFPRFWEN---MNETNVIIIH 275

  Fly   353 G------SFSQELAPQILCEAYRLRMFGADYAWILHESMGAPWWPDQRTACSNHELQLAVENL-- 409
            |      |..:.:..::|..          ..|:::.......:.|.....|.|...:...|.
  Rat   276 GDIDSLESLLRNIGQRLLTR----------NVWVMNIERHVTEFSDYFMLDSFHGSLIFKHNYRE 330

  Fly   410 ------IVVSTHNSIVGNNVSYSGLNNHMFNSQLRKQSAQFHGQDGFGSGYGSRISIAATQSDSR 468
                  .:.:.:.:....::....|.|.:|......::.|..      ....:..|:....|
  Rat   331 KFEFTKFIQTVNPNRYPEDIYLPKLWNLLFKCSFSDRNCQVL------DNCQTNASLDILPS--- 386

  Fly   469 RRRRRGVGGTSGGHLFPEAISQYAPQTYDAVWAIALALRAAEEH-----------------WRRN 516
                         |:|..|:|:.:...|:.|:|:|.:|.....|                 |:.|
  Rat   387 -------------HIFDVAMSEESISIYNGVYAVAHSLHDMRLHQVQMRPYENGEGMIFIPWQLN 438

  Fly   517 EEQSKLDGFDYTRS-------DMAWEFLQQMGKLHFLGVS---GPVSFSGPDRVGTTAFYQI--- 568
            .....|:..| .||       |..::.|........||:.   |..|.:.|.....:...||
  Rat   439 TFLKDLEVRD-NRSLNWIQTIDAEYDILNLWNLPKGLGLKVKIGSFSANAPKGQQLSLSEQIIQW 502

  Fly   569 --------------------QRGLLE--PVALY--YPA--------TDALDFRCPRCRPVKWHSG 601
                                ::..||  |:..|  .|.        ||:  .:|.||....:.:.
  Rat   503 PEIFSKVPQSVCSESCGPGFRKVTLEGKPICCYKCTPCAENEISNETDS--DQCVRCPESHYPNT 565

  Fly   602 QVPIAKRVFKLRVATIAPLAFYTIATLSSVGIALAIAFLAFNL----HFRKLKAIKLSSPKLSNI 662
            :.....:.....:|...||..    .|:|:.:.|: |..||.:    .:|....:|.::..||.|
  Rat   566 EKSNCYQKTSSFLAFEEPLGM----ALASIALCLS-ALTAFVIGIFVKYRDTPIVKANNQALSYI 625

  Fly   663 TAVGCIFVYATVILLGLDHSTLPSAEDSFATVCTARVYLLSAGFSLAFGSMFAKTYRVHRIFTRT 727
            ..:...|.:    |..|:....|:     ...|..:.......|::|..::.||...|...|..:
  Rat   626 LLITLKFCF----LCSLNFIGQPN-----TAACILQQTTFGVAFTVALATVLAKAITVVLAFKVS 681

  Fly   728 GSVFKDKMLQDIQL----ILLVGGLLLVDALLVTLWVV-------TDPMERHLHNLTLEISATDR 781
               |..:|::.:.:    ..:|....|:..||..:|:.       .||...|.|.:.|
  Rat   682 ---FPGRMVRWLMISRGPYYIVPICTLIQLLLCGIWMTMSPPFIDQDPHTEHGHIIIL------- 736

  Fly   782 SVVYQPQVEVCRSQHTQTWLSVLYAYKGLLLVVGVYMAWETRHVKIPALNDSQYIGVSV------ 840
                      |....:..:.:|| .|..||.:....||:.:|::. ...|:|:::.:|:
  Rat   737 ----------CNKGSSLAFHAVL-GYLCLLALGSYTMAFLSRNLP-DTFNESKFLSLSMLVFFCV 789

  Fly   841 --------YSVVITSAIVVVLANLISERVTLAFITITALILTSTTATLCLLFIPKLHDIWARND 896
                    ||   |...|:|...:.|             ||.|:||.|..:|.||.:.|..|.|
  Rat   790 WVTFLPVYYS---TKGKVMVAMEVFS-------------ILASSTALLAFIFGPKCYIILLRPD 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_001245826.1	PBP1_GABAb_receptor	157..590	CDD:107361	99/564 (18%)
		ANF_receptor	174..568	CDD:279440	84/479 (18%)
		7tm_3	633..889	CDD:278433	59/284 (21%)
Vom2r10	NP_001092939.1	PBP1_Pheromone_receptor	40..502	CDD:107360	95/516 (18%)
		NCD3G	511..562	CDD:284890	10/52 (19%)
		7tm_3	597..831	CDD:278433	58/280 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910