Protein Alignment GABA-B-R3 and Vmn2r102

DIOPT Version :9

• Sequence 1: NP_001245826.1
• Gene: GABA-B-R3 / 33248
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: NP_001098034.1
• Gene: Vmn2r102 / 224572
• MGIID: 3647786
• Length: 857
• Species: Mus musculus
• Alignment Length: 851
• Identity: 163/851 - (19%)
• Similarity: 292/851 - (34%)
• Gaps: 233/851 - (27%)

  Fly   177 AATMAVEHINRK-RLLPGYTLELVTNDTQCDPGVGVDRFFHAIYTQPST---------------- 224
            |...|:|.|||. .|||..:|             |.| |::..:|:..|
Mouse    84 ALQFAIEEINRNPNLLPNTSL-------------GFD-FYNVRFTEKYTLDNAFIWLTALVNRKY 134

  Fly   225 --------RMVMLLGSACSEVTES-LAKVVPYWNIVQVSFGSTSPALSDRREFPYFYRTVAPDSS 280
                    |......:..|.:|.: :..::..:...|::||...|.|||..::|..|:....|:|
Mouse   135 FPNYNCKKRNFTAALTGTSWITSAQIGTLLQLFKFPQITFGPYDPLLSDHGQYPSLYQMAPKDTS 199

  Fly   281 HNPARIAFIRKFGWGTVTTFSQNEEVHSLAVNNLVTELEAANISCA------ATITFAATDFKEQ 339
            .:.|.::.|..|.|..|.....::...:..|::...|:|...|..|      ||.|.....|.|.
Mouse   200 LSLAIVSLIAHFRWSWVGLILPDDHKGNKIVSDFREEMERKGICLAFVKMIPATWTSHFAKFWEH 264

  Fly   340 LLLLRETDTRIIIG----------SFSQELAPQILCEAYRLRMFGADYAWILHESMGAPWWPDQR 394
               :.||:..|:.|          :..|.|..|              ..||::
Mouse   265 ---MDETNVTIVYGDVDSLEGVIRNIEQRLLTQ--------------NVWIMN------------ 300

  Fly   395 TACSNHELQLAVENLIVVSTHNSIVGNNVSYSGLNNHMFNSQLRKQSAQFHGQD----------- 448
              ..:|.:..| :..::.:.|.|::   ..:|...|..|...::..:.:.:.:|
Mouse   301 --IEHHVIDRA-DYFMLDTFHGSLI---FKHSYRENFEFTKFIKTVNPKKYPEDIYLPKLWHLFF 359

  Fly   449 --GFGSGYGSRISIAATQSDSRRRRRRGVGGTSGGHLFPEAISQYAPQTYDAVWAIALAL---RA 508
              .|.....:.:....|.:......|         |:|..|:::.:...|:.|:|:|.:|   |.
Mouse   360 KCSFADINCNVLDNCQTNASLDVFPR---------HIFDVAMNEESSSIYNGVYAVAHSLHEMRL 415

  Fly   509 AEEH--------------WRRNE-----EQSKLDGFDYTRS-DMAWEFLQQMGKLHFLGVS---G 550
            .|..              |:.|.     |.......|:.:: |..::.|........||:.   |
Mouse   416 QELQMQPYENGKGIVFFPWQLNRFLKDTEVKDKRCLDWKQTIDTEYDILNLWNLPKGLGLKVKIG 480

  Fly   551 PVSFSGPDRVGTTAFYQIQRGLLEPVALYYP----------ATDALD--FR----------CPRC 593
            ..|.:.|         |.|:..|....:.:|          .:::.:  ||          |.:|
Mouse   481 SFSANAP---------QGQQLSLSEQMIQWPEIFSEIPQSVCSESCEPGFRKVTLEGKAICCYKC 536

  Fly   594 RP---------------VKWHSGQVPIAKR--VFKLRVATIA---PLAFYTIATLSSVGI---AL 635
            .|               ||...|.....:|  .|:..|..:|   ||..    .|:|:.:   :|
Mouse   537 TPCGDNEISNETDVYQCVKCPEGHFANTERNNCFQKSVIFLAYEDPLGM----ALASIALCLSSL 597

  Fly   636 AIAFLAFNLHFRKLKAIKLSSPKLSNITAVGCIFVYATVILLGLDHSTLPSAEDSFATVCTARVY 700
            .:..:...:..|....:|.::..||.|..:...|.:    |..|:....|:     ...|..:..
Mouse   598 TVFVIGIFVKHRDTPIVKANNRALSYILLLTLTFCF----LCSLNFIGQPN-----TATCILQQT 653

  Fly   701 LLSAGFSLAFGSMFAKTYRVHRIFTRTGSVFKDKMLQDIQLI----LLVGGLLLVDALLVTLWVV 761
            ..:..|::|..::.||...|...|..:   |..|:::.:.|.    .::....|:..|:..:|:.
Mouse   654 TFAVTFTMALATVLAKAITVVLAFKVS---FPGKIVRWLMLSRGPNYIIPICTLIQLLICGIWMA 715

  Fly   762 TDPMERHLHNLTLEISATDRSVVYQPQVEVCRSQHTQTWLSVLYAYKGLL--LVVGVY-MAWETR 823
            |.|          .....|....|...:.:|.......:.|||    |.|  |.:|.| ||:.:|
Mouse   716 TSP----------PFIDEDAHTEYGQIIILCNKGSAVAFHSVL----GYLCFLALGSYTMAFLSR 766

  Fly   824 HVKIPALNDSQYIGVSVYSVVITSAIVVVLANLISERVTLAFITITALILTSTTATLCLLFIPKL 888
            ::. ...|:|:|:..|:  :|.....|..|....|.:..:........||.|:||.|..:|.||.
Mouse   767 NLP-DTFNESKYLSFSM--LVFFCVWVTFLPVYHSTKGKIMVAMEVFSILASSTALLAFIFGPKC 828

  Fly   889 HDIWAR 894
            :.|..|
Mouse   829 YIILLR 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_001245826.1	PBP1_GABAb_receptor	157..590	CDD:107361	91/515 (18%)
		ANF_receptor	174..568	CDD:279440	85/471 (18%)
		7tm_3	633..889	CDD:278433	56/265 (21%)
Vmn2r102	NP_001098034.1	PBP1_Pheromone_receptor	39..501	CDD:107360	88/483 (18%)
		ANF_receptor	83..446	CDD:279440	77/419 (18%)
		NCD3G	510..560	CDD:284890	7/49 (14%)
		7tm_3	597..830	CDD:278433	56/261 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910