Protein Alignment GABA-B-R3 and Vmn2r104

DIOPT Version :9

• Sequence 1: NP_001245826.1
• Gene: GABA-B-R3 / 33248
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: NP_001098036.1
• Gene: Vmn2r104 / 22313
• MGIID: 1316665
• Length: 860
• Species: Mus musculus
• Alignment Length: 865
• Identity: 162/865 - (18%)
• Similarity: 301/865 - (34%)
• Gaps: 261/865 - (30%)

  Fly   177 AATMAVEHINRK-RLLPGYTLELVTNDTQCDPGVGVDRFFHAIYTQPS------------TRMVM 228
            |...|:|.|||. .:||..:|             |.| |::..||:.:            .:..|
Mouse    87 ALLFAIEEINRNPNILPNISL-------------GFD-FYNNEYTERNILRFTCRWLTAHVKRAM 137

  Fly   229 LLGSAC------------SEVTES-LAKVVPYWNIVQVSFGSTSPALSDRREFPYFYRTVAPDSS 280
            :....|            |.:|.: :..::..:...|::||...|.|||..::...|:....|:|
Mouse   138 IPNYTCKRRNVIAALTGSSWITSAQIGTLLQLFKFPQITFGPYEPTLSDDGQYSSLYQMAPKDTS 202

  Fly   281 HNPARIAFIRKFGWGTVTTFSQNEEVHSLAVNNLVTELEAANISCA------ATITFAATDFKEQ 339
            .:.|.::|:..|.|..:.....:....:..::....|:|...|..|      ||.|...|.|.|.
Mouse   203 LSLAIVSFMVHFSWSWIGLIIPDNHKGNKILSEFREEMERNKICIAFLKMIPATWTSYFTRFWEN 267

  Fly   340 LLLLRETDTRIIIGSF-SQELAPQILCEAYRLRMFGADYAWILHESMGAPWWPDQRTACSNHELQ 403
               :.||:..||.|.. |.|:..||:  ..||..:.   .||::.              ..|.::
Mouse   268 ---MDETNVIIIYGDIDSLEILMQII--GQRLLTWN---IWIMNN--------------EPHIIE 310

  Fly   404 LAVENLIVVSTHNSIV-----GNNV------------------------------SYSGLNNHMF 433
            |: :..::.|.|.|.:     .:|:                              |:|.:|.|:.
Mouse   311 LS-DYFMLDSFHGSFIFRHNYRDNIEFTKFIQRVNPYKYPEDIYLPKLWNFFFKCSFSDINCHVL 374

  Fly   434 NSQLRKQSAQFHGQDGFGSGYGSRISIAATQSDSRRRRRRGVGGTSGGHLFPEAISQYAPQTYDA 498
            ::  .|.:|.......|                                :|...:|:.:...|:.
Mouse   375 DN--CKTNASLDLLPSF--------------------------------IFDVVMSEESTNIYNG 405

  Fly   499 VWAIA----------LALRAAEE-------HWRRN------EEQSKLDGFDYTRS-DMAWEFLQQ 539
            |:|:|          |.::|.|.       .|:.|      |.:.|.: .|:.:: |..::.|..
Mouse   406 VYALAHSLHQMRLQLLQMQAFENGEEMVFFPWQLNTFLKDIEVKDKRN-LDWKQTIDTEYDILNL 469

  Fly   540 MGKLHFLGVS---GPVSFSGPDRVGTTAFYQIQRGLLEPVALYYP-------------------- 581
            ......||:.   |..|.:.|         |.|:..|....:.:|
Mouse   470 WNLPKGLGLKVKIGSFSANAP---------QGQQLSLSEQIIQWPEIFSEVPQSVCSESCRPGFR 525

  Fly   582 --ATDALDFRCPRCRPVKWH--SGQVPIAKRV---------------FKLRVATIA---PLAFYT 624
              :.|.....|.:|.|...:  |.:..:.:.|               |...|:.:|   ||..
Mouse   526 KVSLDDKAICCYKCTPCADNEISNETDVDQCVKCPESHYANTEKSNCFPKSVSFLAYEDPLGM-- 588

  Fly   625 IATLSSVGI---ALAIAFLAFNLHFRKLKAIKLSSPKLSNITAVGCIFVYATVILLGLDHSTLPS 686
              .|:|:.:   ||.:..:...:..|....:|.::..||.|..:...|.:    |..|:....|:
Mouse   589 --ALASIALCLSALTVFVIGIFVKNRDTPIVKANNRTLSYILLITLTFCF----LCSLNFIGQPN 647

  Fly   687 AEDSFATVCTARVYLLSAGFSLAFGSMFAKTYRVHRIFTRTGSVFKDKMLQDIQLI----LLVGG 747
                 ...|..:....:..|::|..::.||...|...|..:   |..:||:.:.:.    .::..
Mouse   648 -----TAACILQQTTFAVAFTMALATVLAKAITVVLAFKIS---FPGRMLRWLMISRGPRYIIPI 704

  Fly   748 LLLVDALLVTLWVVTDPMERHLHNLTLEISATDRSVVYQPQVEVCRSQHTQTWLSVLYAYKGLL- 811
            ..|:..||..:|:.|.|     ..:..:::..|..::.     :|.......:.|||    |.|
Mouse   705 CTLIQLLLCGIWMATSP-----PFIDQDVNTEDGYIIL-----LCNKGSAVAFHSVL----GYLC 755

  Fly   812 -LVVGVY-MAWETRHVKIPALNDSQYIGVSVYSVVITSAIVVVLANLISERVTLAFITITALILT 874
             |.:|.| ||:.:|::. ...|:|:::..|:..........:.:.:....:|.:|....:  ||.
Mouse   756 FLALGSYTMAFLSRNLP-DTFNESKFLSFSMLVFFCVWVTFLPVYHSTKGKVMVAMEVFS--ILA 817

  Fly   875 STTATLCLLFIPKLHDIWAR 894
            |:||.|..:|.||.:.|..|
Mouse   818 SSTALLAFIFGPKCYIILLR 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_001245826.1	PBP1_GABAb_receptor	157..590	CDD:107361	94/529 (18%)
		ANF_receptor	174..568	CDD:279440	89/485 (18%)
		7tm_3	633..889	CDD:278433	54/265 (20%)
Vmn2r104	NP_001098036.1	PBP1_Pheromone_receptor	43..504	CDD:107360	92/497 (19%)
		ANF_receptor	86..469	CDD:279440	84/453 (19%)
		NCD3G	513..564	CDD:284890	6/50 (12%)
		7tm_3	599..833	CDD:278433	54/262 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910