Protein Alignment GABA-B-R3 and LOC100490505

DIOPT Version :9

• Sequence 1: NP_001245826.1
• Gene: GABA-B-R3 / 33248
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: XP_012811543.1
• Gene: LOC100490505 / 100490505
• -ID: -
• Length: 878
• Species: Xenopus tropicalis
• Alignment Length: 889
• Identity: 183/889 - (20%)
• Similarity: 314/889 - (35%)
• Gaps: 276/889 - (31%)

  Fly   167 PRPDGLSELGAATMAVEHINR-KRLLPGYTLELVTNDTQCDPGVGVDRFFHAI---------YTQ 221
            |.|:...:......|:|..|. ..|||..||....:|:..||...|......:         |:.
 Frog    81 PLPEYYRQFVDFHFAIEKSNNDPLLLPNLTLGYHISDSCGDPRKAVRSVLQILSGTREPVPNYSC 145

  Fly   222 PSTRMVM-LLGSACSEVTESLAKVVPYWNIVQVSFGSTSPALSDRREFPYFYRTVAPDSSHNPAR 285
            ...|.:. .:|...||.|..:|:::..:...|:|:|:|..:||||..||||:||:..|..|..:.
 Frog   146 VGKRNIAGFIGDLSSETTVPIAQILTLYGYSQISYGATDTSLSDRVTFPYFFRTLQSDHGHYFSL 210

  Fly   286 IAFIRKFG--W-GTVTT--FSQNEEV----HSLAVNNLVTELEAANISCAATITFAATDFKEQL- 340
            ...::.||  | |.:|:  .|..:|:    :.|:::.:..|. ...||.......|..:.:..|
 Frog   211 SKLLKAFGGNWVGIITSDDISGEKELQILTNYLSIDGICVEF-TIKISDNMDDISAVGNIRHHLP 274

  Fly   341 --LLLRETDTRIIIGSFSQELAPQILCEAYRLRMFG--ADYAWILHESMGAPWWPDQRTACSNHE 401
              .:::::.|.::           |||....|.:.|  ..|..:|.|.:
 Frog   275 YKNIIQKSTTNVV-----------ILCGKISLGVIGKLIIYTDVLSEKI---------------- 312

  Fly   402 LQLAVENLIVVSTHNSIVGNNVSYSGLNNHMFNSQLRKQSAQFHGQDGFGSGYGSRISIAATQSD 466
                   |:|..|..|           .||:.:..|.    .|....||       :..:|...|
 Frog   313 -------LVVSPTLTS-----------KNHIIDYSLE----IFSNILGF-------VQHSAYSVD 348

  Fly   467 SRRRRRRGVGGTSGGHLFPEAISQYAPQTY------DAVWAIALALRAAEEH------------- 512
            ||.              ....:..:.|.||      :.:|.:.....:.::|
 Frog   349 SRE--------------ITHYLESFRPSTYPEDKLLEDIWLLYHLCLSKQQHKNYLYANLYKYEL 399

  Fly   513 -----WRRNEEQSKLDGFDYTRS-----DMAWEFLQQM------------------------GKL 543
                 .:|..:....|...|:.|     ||....:..|                        .||
 Frog   400 HNCTGQKRITDIRHFDSKLYSPSVALAVDMMSHAIHAMHISLAERPPENRKQMYKYQVNIYLNKL 464

  Fly   544 HFLGVSG-PVSFSGPDRVGTTAFYQIQRGLLEP---VALYYPAT----DALDFRCP-RCRPVKW- 598
            |:....| .|||.....:.|  :|.|...:|||   :::.|..|    |.||.:.. |...:.|
 Frog   465 HYKTTGGTTVSFEKNGELVT--WYMIYNCILEPNNQISVNYLGTFQPRDPLDDKSMIRSHQIIWI 527

  Fly   599 -HSGQVPIA----------KRVFKLRVATIAPLAFYTIATLSSVGIALAI--------------- 637
             :..|:|.|          ::|.::|    |....|..|..|...|:.|.
 Frog   528 SNKSQIPSAQCSASCLPGLRKVPRIR----AQPCCYDCAQCSEGDISNATDSENCYKCPDMEWPN 588

  Fly   638 -----------AFLAFNLHFRKLKAIKLSSPKLSNITAVGCIFV-YATVILLG------------ 678
                       .||:::.|            ::|.:.....:|: ..||:::|
 Frog   589 EKRDQCILKSEDFLSYSNH------------EISMLFGSVSLFLSVLTVLIMGIFLKYRDTPIVR 641

  Fly   679 -----LDHSTLPSAEDSFATV-----------CTARVYLLSAGFSLAFGSMFAKTYRVHRIF--T 725
                 |....|.|.:.||.:|           |..|:......||:|..|:.|||..|...|  |
 Frog   642 ANNRSLSFLLLVSIKLSFLSVFLFLGRPVDITCMLRIITFGITFSIAVSSLLAKTIMVCVAFKAT 706

  Fly   726 RTGSVFKD----KMLQDIQLILLVGGLLLVDALLVTLWVVTDPMERHLHNLTLEISATDRSVVYQ 786
            :.||.::.    |:...:  :|....:.::  :.:|...::.|.:.      |:|..:..:::.|
 Frog   707 KPGSSWRKWLGVKLSNSV--VLFCSSIQII--ICMTWLAISPPFQE------LDIHTSPGTIIIQ 761

  Fly   787 PQVEVCRSQHTQTWLSVLYAYKGLLLVVGVYMAWETRHVKIP-ALNDSQYIGVSVY---SVVITS 847
                 |.......:.||: .|.|||..|...:|:..|  .:| :.|:::||..|:.   ||.||
 Frog   762 -----CNEGSAIGFYSVI-GYMGLLAAVSFVLAFLAR--SLPDSFNEAKYITFSMLLFCSVWIT- 817

  Fly   848 AIVVVLANLISERVTLAFITITALILTSTTATLCLLFIPKLHDI 891
               ::.|.|.::......:.|.| ||||:...|..:|:||.:.|
 Frog   818 ---MIPAYLSTKGKNTVCVEIFA-ILTSSAGLLACIFLPKCYII 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_001245826.1	PBP1_GABAb_receptor	157..590	CDD:107361	103/508 (20%)
		ANF_receptor	174..568	CDD:279440	92/472 (19%)
		7tm_3	633..889	CDD:278433	68/320 (21%)
LOC100490505	XP_012811543.1	Periplasmic_Binding_Protein_Type_1	49..526	CDD:299141	104/517 (20%)
		ANF_receptor	94..483	CDD:279440	90/459 (20%)
		NCD3G	535..586	CDD:284890	9/54 (17%)
		7tm_3	622..856	CDD:278433	61/256 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910