Protein Alignment GABA-B-R3 and olfcg7

DIOPT Version :10

• Sequence 1: NP_523447.2
• Gene: GABA-B-R3 / 33248
• FlyBaseID: FBgn0031275
• Length: 1305
• Species: Drosophila melanogaster
• Sequence 2: NP_001353272.1
• Gene: olfcg7 / 100149870
• ZFINID: ZDB-GENE-081029-5
• Length: 851
• Species: Danio rerio
• Alignment Length: 907
• Identity: 173/907 - (19%)
• Similarity: 328/907 - (36%)
• Gaps: 254/907 - (28%)

  Fly   151 GKIVLLGLFELST---------SRGPRPDGLSELG------AATM--AVEHINR-KRLLPGYTLE 197
            |.:.:.|:|.:.:         .:.|:|...|.:.      |..|  |:|.||: :.|||..::.
Zfish    52 GDVTIGGIFAIHSKETLPSFEFQQKPQPLLCSSVNLRDFRLAQIMIFAIEEINKSENLLPNVSIG 116

  Fly   198 LVTNDT--------QCDPGVGVDRFFHAIYT-QPSTRMVMLLGSACSEVTESLAKVVPYWNIVQV 253
            ....||        ....|:..:..|.|..| ...:.:..::|...|..|..|::....:.|..:
Zfish   117 YRIFDTCGSRLSSMSATMGLMNELKFAAGETCNGQSPIHAIIGETESSATVILSRTTGPFKIPVI 181

  Fly   254 SFGSTSPALSDRREFPYFYRTVAPDSSHNPARIAFIRKF-GWGTVTTFSQNEEVHSLAVNNLVTE 317
            |..::...||:|.::|.|:||::.| .|....:|:|.|: ||..|...:.:.:..:..:...:..
Zfish   182 SHSASCECLSNRNDYPSFFRTISSD-YHQGRALAYIVKYLGWSWVGAVNSDNDYGNYGMAIFLET 245

  Fly   318 LEAANISCAATITFAATD---FKEQLLLLRETDTRIIIGSFSQELAPQILCEAYRLRMFGADYAW 379
            .:...|....::.|..|:   .|..:..::::..::|: :|...:...:|.|
Zfish   246 AQKEGICVEYSVKFYRTETEKLKRVVDTIKKSTAKVIV-AFVSFIEMGLLIE------------- 296

  Fly   380 ILHESMGAPWWPDQRTACSNHELQLAVENLI---VVSTHNSIVGNNVSYSGLNN-HMFNSQLRKQ 440
                                   ||:::|:.   ::.....|...|  |...|: |.....|...
Zfish   297 -----------------------QLSIQNITGFQIIGVEGWITSKN--YITTNSFHSMGGSLGLA 336

  Fly   441 SAQFHGQDGF-----GSGYGSRISIAATQSDSRRRRRRGVGGTSGGHLFPEAI-----------S 489
            ..:.| .:||     .|.:.:....:.|:         |:..|.|...:.:.:           .
Zfish   337 LRKIH-LEGFLDYVTKSFWSTAFPCSQTE---------GILPTVGCSKYKDLLPLKNYTEDVPEH 391

  Fly   490 QYAPQTYDAVWAIALALRAAEEHWRRNEEQSKLDGFDYTRSDMAWEFLQQMGKLHFLGVSGP-VS 553
            :|:...|.|::|:|.:|.:..: .:..|:..|      ..:....:.::.:.|::|....|. |.
Zfish   392 RYSSHVYKAIYAVAHSLHSLLK-CKEGEDCEK------GHATQPQQVVEALKKVNFTVKFGDRVW 449

  Fly   554 FSGPDRVG-TTAFYQI--------------------------QRGLLEPVALYYPA--------- 582
            |   ||.| |.|.|::                          ||.:|...::.:|.
Zfish   450 F---DRTGATVAHYEVVNWQQDTDGSFQFKQVGYYDASLPPDQRFVLNIESIIWPGGNLEKPRSV 511

  Fly   583 -----------------------------------TDALDFRCPRCRPVKWHSGQVPIAKRVFKL 612
                                               ||:::  |.:|....|.:|:.  .|.|.|
Zfish   512 CSESCSPGTRKAAQKGRPVCCYDCVPCADGEISNETDSVN--CKQCPREYWSNGEK--NKCVLK- 571

  Fly   613 RVATIAPLAFYTIA-------TLSSVGIALAIAFLAFNLHFRKLKA--IKLSSPKLSNITAVGCI 668
               .|..|:|..|.       :|..||:...:|.|.::    |:..  :|.::.:||.:    .:
Zfish   572 ---AIEFLSFTEIMGIVLVCFSLFGVGLTAVVAILFWS----KMDTPIVKANNSELSFL----LL 625

  Fly   669 FVYATVILLGLDHSTLPSAEDSFATVCTARVYLLSAGFSLAFGSMFAKTYRVHRIFTRT--GSVF 731
            |......|..|.....|:...     |..|.......|.|....:..||..|..:|..|  ||..
Zfish   626 FSLTLCFLCSLTFIGRPTEWS-----CMLRHTAFGITFVLCISCVLGKTIVVLMVFKATLPGSNV 685

  Fly   732 KDKMLQDIQLILLVGGLLLVDALLVTLWVVTDPMERHLHNLTLEISATDRSVVYQPQVEV-CRSQ 795
            . |.....|..|.|.....:..|:..||:...|...: .|:|          .|:.::.: |...
Zfish   686 M-KWFGPTQQRLSVLAFTFIQVLICVLWLTISPPFPN-KNMT----------YYKEKIIIECSLG 738

  Fly   796 HTQTWLSVLYAYKGLLLVVGVYMAWETRHVKIP-ALNDSQYIGVSVYSVVITSAI-VVVLANLIS 858
            .|.::.:|| .|.|||.|:...:|:..|  |:| ..|::::|   .:|::|..|: :..:...:|
Zfish   739 STISFWAVL-GYIGLLAVLCFILAFLAR--KLPDNFNEAKFI---TFSMLIFCAVWITFIPAYVS 797

  Fly   859 E--RVTLAFITITALILTSTTATLCLLFIPKLHDIWARNDIIDPVIHSMGLKMECNTRRFVV 918
            .  :.|:| :.|.|::.:|....|| :|.||.:.|..              |.|.||::.|:
Zfish   798 SPGKFTVA-VEIFAILASSFGLLLC-IFAPKCYIIIC--------------KPEQNTKQHVM 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R3	NP_523447.2	PBP1_GABAb_receptor	156..600	CDD:380589	94/566 (17%)
		7tmC_GABA-B-like	621..892	CDD:320175	66/286 (23%)
		TM helix 1	621..645	CDD:320175	7/30 (23%)
		TM helix 2	657..678	CDD:320175	4/20 (20%)
		TM helix 3	696..720	CDD:320175	5/23 (22%)
		TM helix 4	741..761	CDD:320175	5/19 (26%)
		TM helix 5	797..823	CDD:320175	9/25 (36%)
		TM helix 6	832..855	CDD:320175	4/23 (17%)
		TM helix 7	862..887	CDD:320175	8/24 (33%)
olfcg7	NP_001353272.1	Periplasmic_Binding_Protein_type1	56..500	CDD:471960	88/503 (17%)
		NCD3G	508..561	CDD:462210	4/54 (7%)
		7tmC_V2R_pheromone	582..831	CDD:320410	64/281 (23%)
		TM helix 1	582..606	CDD:320410	5/23 (22%)
		TM helix 2	618..639	CDD:320410	5/24 (21%)
		TM helix 3	648..672	CDD:320410	5/23 (22%)
		TM helix 4	696..712	CDD:320410	3/15 (20%)
		TM helix 5	739..765	CDD:320410	9/26 (35%)
		TM helix 6	773..796	CDD:320410	4/25 (16%)
		TM helix 7	801..826	CDD:320410	8/26 (31%)