Protein Alignment Eaat2 and tcyP

DIOPT Version :10

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_416243.1
• Gene: tcyP / 946238
• ECOCYCID: G6934
• Length: 463
• Species: Escherichia coli
• Alignment Length: 509
• Identity: 122/509 - (23%)
• Similarity: 219/509 - (43%)
• Gaps: 106/509 - (20%)

  Fly    40 TGYRRW-LSENLMLLVTLSGVLLGVILGLSLRPLNLHG-------DSIMLISYPGELFMRVLKLM 96
            |.:::| |::.:::     |:::||:.||:|.  .::|       ||:...:..|..::::|:::
E. coli    22 TRHKQWSLAKKVLV-----GLVMGVVFGLALH--TIYGSDSQVLKDSVQWFNIVGNGYVQLLQMI 79

  Fly    97 ILPLVISSLIAGSASL-NAKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPGNPDLHNADDRS 160
            ::|||.:|:::..|.| ||...|||:..|:.....|:...|.:|:.:..|.......|......:
E. coli    80 VMPLVFASILSAVARLHNASQLGKISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAET 144

  Fly   161 TDRRAV--NLLDSLLDLGRNVFPDNLFQASIQQAHTVYLPKPSILHVFNETMNDTLASGSEAQRL 223
            ....|:  |.:..:.||            |:.|....::||...
E. coli   145 ARLNAIESNYVGKVSDL------------SVPQLVLSFIPKNPF--------------------- 176

  Fly   224 SEDLTEDVVLVRDIQYRSGTNTLGIVFFCLVFGTFLGTI--------GQKGQVVVDFFAAIFEVI 280
             .|||             |.|...|: ..::|..|||..        ..||:.|:.....:...:
E. coli   177 -ADLT-------------GANPTSII-SVVIFAAFLGVAALKLLKDDAPKGERVLAAIDTLQSWV 226

  Fly   281 MKMVTCVMWLTPVGI----SSVIAGK----ILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQA 337
            ||:|..||.|||.|:    :.|:||.    |:.:|.          |:|...:|:     ::|.|
E. coli   227 MKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGS----------FVVASYLGL-----LIMFA 276

  Fly   338 IYFVVVRRN---PFKFYAGLIQAMLTAFATASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNI 399
            ::.:::..|   |.|::..:...:..||.:.|:||::|:.......:|.|...|..|....|..|
E. coli   277 VHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFAASFGATI 341

  Fly   400 NMDGTA-LYIAVASIFIAQMSGM-VLGFGELLTVLLTSTAASMSSASVPSAALVLLLVVLTAIDA 462
            ..:|.| ||.|:.::.:|...|: .|....:.|::...|.:|...|.|...|....|:||.|:..
E. coli   342 GQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGGATFAALIVLPAMGL 406

  Fly   463 PVQDVTLLFAVDWFVDRIRTTNNMLGDCYTAAVVEELSRKELMALDAASVNYQD 516
            ||..|.||.:|:..:|..||..|:.|. .||..   |:.:.|...|.|.::.:|
E. coli   407 PVTLVALLISVEPLIDMGRTALNVSGS-MTAGT---LTSQWLKQTDKAILDSED 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..499	CDD:425646	114/478 (24%)
tcyP	NP_416243.1	TcyP	1..463	CDD:441428	122/509 (24%)