Protein Alignment Eaat2 and slc1a2a

DIOPT Version :10

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001177234.1
• Gene: slc1a2a / 560802
• ZFINID: ZDB-GENE-100422-11
• Length: 548
• Species: Danio rerio
• Alignment Length: 517
• Identity: 225/517 - (43%)
• Similarity: 335/517 - (64%)
• Gaps: 23/517 - (4%)

  Fly    46 LSENLMLLVTLSGVLLGVILGLSLRPLN-LHGDSIMLISYPGELFMRVLKLMILPLVISSLIAGS 109
            |.:||:|.:|:.||:.|.:.|:.||..: |..|.||:|::||::.||:||::||||:|||||.|.
Zfish    32 LMKNLLLTLTVLGVITGSVAGILLRYASPLPADVIMVIAFPGDILMRMLKMVILPLIISSLITGL 96

  Fly   110 ASLNAKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPGNPDL--HNADDRSTDRRAVNLLDSL 172
            |.|:||.:|::..|.::|:.||:...|.||:.||||||||||.|  :..:.:..|.  |:.||:.
Zfish    97 AGLDAKSSGRLGTRAMIYYMSTTVIAAVLGVILVLLIHPGNPKLKANLGEGKKNDE--VSSLDAF 159

  Fly   173 LDLGRNVFPDNLFQASIQQAHTVYLPKPSILHVFNETMNDTLASGSEAQRLSEDLTEDV---VLV 234
            .||.||:||:||.||..||..||             |....:|......|...:.|:..   |:.
Zfish   160 FDLIRNLFPENLVQACFQQIQTV-------------TTKVEIAPPPPPTRFGRNATKGAAKYVIK 211

  Fly   235 RDIQYRSGTNTLGIVFFCLVFGTFLGTIGQKGQVVVDFFAAIFEVIMKMVTCVMWLTPVGISSVI 299
            :.:|::||.|.|||:.|.:.||..:|.:|:|.:::||||..:.|::|::|..:||.:|:||:.:|
Zfish   212 KSLQFKSGMNVLGIIGFFVAFGICMGKMGEKAKLMVDFFNTLNEIVMRLVGMIMWYSPIGIACLI 276

  Fly   300 AGKILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQAIYFVVVRRNPFKFYAGLIQAMLTAFAT 364
            .|||:|:.||.:|..||..::|||.:|:.|:..:.:..||||:||:|||||:.||.||.:||..|
Zfish   277 CGKIISINDLEMVAKQLGMYMVTVIVGLIIHGGIFLPLIYFVIVRKNPFKFFMGLFQAWVTALGT 341

  Fly   365 ASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNINMDGTALYIAVASIFIAQMSGMVLGFGELL 429
            ||:|..||:||||:.|.|.:|.|:||||||:|..|||||||||.|||:||||||:|:.|..|:::
Zfish   342 ASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIELDPGQIV 406

  Fly   430 TVLLTSTAASMSSASVPSAALVLLLVVLTAIDAPVQDVTLLFAVDWFVDRIRTTNNMLGDCYTAA 494
            ||.||:|.||:.:||:|||.||.:|::|||:..|.||::||.||||.:||.||:.|::||.|.|.
Zfish   407 TVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVIGDSYGAG 471

  Fly   495 VVEELSRKELMALDAASVNYQDMPAGTPNGHGHGHGHHDGGLLEGQTELETSSKCVMTMTDS 556
            :|..||:.||...||..:...|........:...:.:|  |:.....:......|.:|:..:
Zfish   472 IVYHLSKDELDMFDAQQIRPDDFEMAKTQSYYENNSNH--GVYHNSCQPIQIDDCKVTLASN 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..499	CDD:425646	211/453 (47%)
slc1a2a	NP_001177234.1	GltP	46..473	CDD:440912	206/441 (47%)