Protein Alignment Eaat2 and slc1a5

DIOPT Version :9

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001008127.1
• Gene: slc1a5 / 493489
• XenbaseID: XB-GENE-482596
• Length: 527
• Species: Xenopus tropicalis
• Alignment Length: 516
• Identity: 181/516 - (35%)
• Similarity: 300/516 - (58%)
• Gaps: 35/516 - (6%)

  Fly    20 PTSTELPP---KTTECSDAPVELTGYRRWLSENLMLLVTLSGVLLGVILGLSLRPLNLHGDSIML 81
            |....:||   ::.|.:.:|......||:|..|:::|:|:.||::|..||:::||||:....|..
 Frog    12 PGEHPVPPGLHRSGESASSPGCGPRCRRFLRGNVLVLLTVLGVIMGAGLGMAVRPLNMSKAHIAS 76

  Fly    82 ISYPGELFMRVLKLMILPLVISSLIAGSASLNAKMNGKIALRTLVYFASTSFFNAALGIALVLLI 146
            .|:||||.:|:||::|||||:.||::|:|||.....||:....:::|..|:...:.||:.|.|||
 Frog    77 FSFPGELLLRLLKMIILPLVVCSLVSGAASLQPSALGKLGGWAMLFFLITTLLASGLGVCLALLI 141

  Fly   147 HPGNPDLHNADDRSTDRRAVNLLDSLLDLGRNVFPDNLFQASIQQAHTVYLPKPSILHV-FNETM 210
            .||..................::||.|||.||:||.||..|:.|...|.|  |..:::. .|..|
 Frog   142 RPGVGAQVALGQGGGIPEGKEVVDSFLDLIRNIFPSNLVSAAFQSYATSY--KLELVNTSANGEM 204

  Fly   211 NDT---LASGSEAQRLSEDLTEDVVLVRDIQYRSGTNTLGIVFFCLVFGTFLGTIGQKGQVVVDF 272
            |:|   :..|.|.:                    |.|.||:|.|.:|||..|..:|.:|::::.|
 Frog   205 NNTWVKVPYGQEVE--------------------GMNILGLVVFAIVFGIALRKLGPEGEILIRF 249

  Fly   273 FAAIFEVIMKMVTCVMWLTPVGISSVIAGKILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQA 337
            |.:..|..|.:||.:||..|:||..::||||:.:.|:..:.:.|..:|....:|..|:..:|:..
 Frog   250 FNSFNEATMVLVTWIMWYAPLGIMFLVAGKIVEMEDVVQLFTSLGKYISCCIVGHIIHGLLVLPL 314

  Fly   338 IYFVVVRRNPFKFYAGLIQAMLTAFATASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNINMD 402
            |||...|:||::|..|::.|:.|||.|:|::|.||:..:|:.|:..|..:|:||:||||..:|||
 Frog   315 IYFAFTRKNPYRFLWGIVSALATAFGTSSSSATLPLMMKCVEERNGVSKQISRFILPIGATVNMD 379

  Fly   403 GTALYIAVASIFIAQMSGMVLGFGELLTVLLTSTAASMSSASVPSAALVLLLVVLTAIDAPVQDV 467
            |.||:..||::||||::.:.|.|.:::|:|:|:||:|:.:|.:|:..::.|.::|.|:..|..|:
 Frog   380 GAALFQCVAAVFIAQLNNVSLDFIQIITILVTATASSVGAAGIPAGGVLTLAIILEAVSLPTNDI 444

  Fly   468 TLLFAVDWFVDRIRTTNNMLGDCYTAAVVEELSRKELMA---LDAASVNYQ---DMPAGTP 522
            :|:.||||.|||..|..|:.||.:.|.:::..|.:...:   .:.|:|..:   |.|.|.|
 Frog   445 SLILAVDWLVDRTCTVLNVEGDAFGAGLLQVYSDRTASSSEGTELAAVQVEIPGDHPEGDP 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..496	CDD:278787	165/448 (37%)
slc1a5	NP_001008127.1	SDF	55..473	CDD:366058	161/439 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930