Protein Alignment Eaat2 and slc1a2b

DIOPT Version :9

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_956273.2
• Gene: slc1a2b / 335836
• ZFINID: ZDB-GENE-030131-7779
• Length: 562
• Species: Danio rerio
• Alignment Length: 537
• Identity: 228/537 - (42%)
• Similarity: 349/537 - (64%)
• Gaps: 30/537 - (5%)

  Fly    36 PVELTGYRRW------LSENLMLLVTLSGVLLGVILGLSLRPLNLHGDSI-MLISYPGELFMRVL 93
            |:|.....:|      :.:||:|.:|:.||::|.:.|:.||..:...|:| |:|::||::.||:|
Zfish    17 PIEARPLSKWGTICQKMRKNLLLTLTVMGVIMGAVSGMLLRVASPIDDNIVMVIAFPGDILMRML 81

  Fly    94 KLMILPLVISSLIAGSASLNAKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPGNPDLHNADD 158
            |::||||:|||||.|.|.|:||.:|::..|.::|:.:|:...|.||:.||||||||||.|.....
Zfish    82 KMLILPLIISSLITGLAGLDAKSSGRLGSRAMIYYMTTTVIAAVLGVILVLLIHPGNPKLKENLG 146

  Fly   159 RSTDRRAVNLLDSLLDLGRNVFPDNLFQASIQQAHTVYLPKPSI---LHVFNETMNDTLASGSEA 220
            ...:...|:.||:..||.||:||:||.||..||..|| :.|..:   |...|.||::.|::.::.
Zfish   147 EGLENDEVSSLDAFFDLIRNLFPENLVQACFQQIQTV-VKKVEVQPDLDDTNSTMSEYLSNATKP 210

  Fly   221 QRLSEDLTEDVVLVRDIQYRSGTNTLGIVFFCLVFGTFLGTIGQKGQVVVDFFAAIFEVIMKMVT 285
            ..:.:|       .:.:|::||.|.||::.|.:.||..:|.:|:|.::::|||..:.|::||:|.
Zfish   211 PPIFKD-------KKSLQFKSGMNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVI 268

  Fly   286 CVMWLTPVGISSVIAGKILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQAIYFVVVRRNPFKF 350
            .:||.:|.||:.:|.|||:|:.||.:|..||..:::||.:|:.|:..:.:..|||.:||:|||.|
Zfish   269 MIMWYSPFGIACLICGKIISIKDLEVVARQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSF 333

  Fly   351 YAGLIQAMLTAFATASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNINMDGTALYIAVASIFI 415
            :.|:.||.:||..|||:|..||:||||:.|.|.:|.|:||||||:|..|||||||||.|||:|||
Zfish   334 FMGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFI 398

  Fly   416 AQMSGMVLGFGELLTVLLTSTAASMSSASVPSAALVLLLVVLTAIDAPVQDVTLLFAVDWFVDRI 480
            |||:|:.|..|:::||.||:|.||:.:||:|||.||.:|::|||:..|.||::||.||||.:||.
Zfish   399 AQMNGIDLDPGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRF 463

  Fly   481 RTTNNMLGDCYTAAVVEELSRKELMALDAASVNYQD--MPAGTPNGHGHGHGHHDGGLLEGQTEL 543
            ||:.|::||.|.|.:|..||:.||.||||......|  |...|.:.:.....||:
Zfish   464 RTSVNVVGDSYGAGIVYHLSKAELDALDAQHGKTDDIEMMTKTQSYYDDLKNHHE---------- 518

  Fly   544 ETSSKCVMTMTDSVVVD 560
            ..|::||....::.:||
Zfish   519 NNSNQCVFAAQNTGLVD 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..496	CDD:278787	204/448 (46%)
slc1a2b	NP_956273.2	SDF	38..482	CDD:278787	205/451 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	411	1.000	Domainoid score	I653
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	431	1.000	Inparanoid score	I1691
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	1	1.000	-	-		otm25669
orthoMCL	1	0.900	-	-		OOG6_100309
Panther	1	1.100	-	-	O	PTHR11958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X191
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.980