Protein Alignment Eaat2 and slc1a3a

DIOPT Version :10

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_997805.1
• Gene: slc1a3a / 323439
• ZFINID: ZDB-GENE-030131-2159
• Length: 537
• Species: Danio rerio
• Alignment Length: 493
• Identity: 211/493 - (42%)
• Similarity: 322/493 - (65%)
• Gaps: 19/493 - (3%)

  Fly    21 TSTELPPKTTECSDAPVELTGYRRWLSENLMLLVTLSGVLLGVILGLSLRPLNLHGDSIMLISYP 85
            |...|..|.|..:.:..::.|:   ...|..:::|::.|::|:|||..|||..:....:...|:|
Zfish    23 TERSLRAKNTVQNISSNDVKGF---FMRNAFVILTVAAVIVGIILGFGLRPYKMSYREVKYFSFP 84

  Fly    86 GELFMRVLKLMILPLVISSLIAGSASLNAKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPGN 150
            |||.||:|::::|||::||||.|.|:|:::.:||:.:|.:||:.:|:.....:||.:||:||||.
Zfish    85 GELLMRMLQMLVLPLLVSSLITGMAALDSRASGKMGVRAVVYYTTTTIIAVFIGIVMVLIIHPGK 149

  Fly   151 PDLHNADDRSTDRRAVNLL---DSLLDLGRNVFPDNLFQASIQQAHTVYLPKPSILHVFNETMND 212
                .:.|..|....:..:   |:.|||.||:||.||.||..||..|.|..:...:.|.   :||
Zfish   150 ----GSKDEFTKHEKIEQVSPADAFLDLIRNMFPPNLVQACTQQFKTQYGKRVVTVKVL---VND 207

  Fly   213 TLAS-GSEAQRLSEDLTEDVVLVRDIQYRSGTNTLGIVFFCLVFGTFLGTIGQKGQVVVDFFAAI 276
            |:.| .:..|.|..   |:|:.|  :...:|.|.||:|.|.:.||..:|.:.::||.:.|||..:
Zfish   208 TVFSLNNGTQELKR---EEVIPV--LGTVNGINALGLVVFSMCFGLIIGNMKEQGQPLRDFFDCL 267

  Fly   277 FEVIMKMVTCVMWLTPVGISSVIAGKILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQAIYFV 341
            .|.||::|..:||..|:||..:|||||:.:.||..:..||..:.:||.||:.|:..:|:..:||:
Zfish   268 NEAIMRLVAIIMWYAPLGIMFLIAGKIVEMDDLSEMGGQLGMYTITVIIGLLIHAVIVLPLLYFL 332

  Fly   342 VVRRNPFKFYAGLIQAMLTAFATASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNINMDGTAL 406
            |.|:|||.|.|||:||::||..|:|::|.|||||:|:.|...||.|:||||||:|..||||||||
Zfish   333 VTRKNPFVFIAGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTAL 397

  Fly   407 YIAVASIFIAQMSGMVLGFGELLTVLLTSTAASMSSASVPSAALVLLLVVLTAIDAPVQDVTLLF 471
            |.|:|:|||||::.|.:.|||:||:.:|:||||:.:|.:|.|.||.:::|||::..|..|:||:.
Zfish   398 YEALAAIFIAQVNDMEMNFGEILTISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLII 462

  Fly   472 AVDWFVDRIRTTNNMLGDCYTAAVVEELSRKELMALDA 509
            |||||:||:|||.|:|||...|.:||.|||.||.::||
Zfish   463 AVDWFLDRLRTTTNVLGDSIGAGIVEHLSRHELRSIDA 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..499	CDD:425646	198/451 (44%)
slc1a3a	NP_997805.1	GltP	46..507	CDD:440912	206/467 (44%)