Protein Alignment Eaat2 and Slc1a5

DIOPT Version :10

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_786934.1
• Gene: Slc1a5 / 292657
• RGDID: 708512
• Length: 539
• Species: Rattus norvegicus
• Alignment Length: 505
• Identity: 170/505 - (33%)
• Similarity: 286/505 - (56%)
• Gaps: 59/505 - (11%)

  Fly    44 RWLSENLMLLVTLSGVLLGVILGLSLRPLN----LHGDSIMLISYPGELFMRVLKLMILPLVISS 104
            |.|..||::|:|::..:.||:|||.:....    |........::||||.:|:|:::|||||:.|
  Rat    48 RCLRANLLVLLTVAAAVAGVVLGLGVSAAGGAEALGHARFTAFAFPGELLLRLLEMIILPLVVCS 112

  Fly   105 LIAGSASLNAKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPG-----------NPDLHNADD 158
            ||.|:|||:....|::....|::|..|:..::|||:||.|.:.||           :..:|.|..
  Rat   113 LIGGAASLDPSALGRLGAWALLFFLVTTLLSSALGVALALALKPGAAFAAINSSVVDSSVHRAPT 177

  Fly   159 RSTDRRAVNLLDSLLDLGRNVFPDNLFQASIQQAHTVYLPKPSILHVFNETMNDTLASGSEAQRL 223
            :       .:|||.|:|.||:||.||..||.               .|.      :..|:..||.
  Rat   178 K-------EVLDSFLELLRNMFPSNLVSASA---------------AFR------IPCGACPQRS 214

  Fly   224 SEDLTEDVVLVRDIQYRSGTNTLGIVFFCLVFGTFLGTIGQKGQVVVDFFAAIFEVIMKMVTCVM 288
            :..:.:....::       .|.||:|.|.:|||..|..:|.:|::::.||.:..:..|.:|:.:|
  Rat   215 NATMDQPHCEMK-------MNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDATMVLVSWIM 272

  Fly   289 WLTPVGISSVIAGKILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQAIYFVVVRRNPFKFYAG 353
            |..|:||..::||||:.:.|:..:...|..:||...:|..|:..:|:..|||:..|:||::|..|
  Rat   273 WYAPIGILFLVAGKIVEMKDIRQLFIGLGKYIVCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWG 337

  Fly   354 LIQAMLTAFATASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNINMDGTALYIAVASIFIAQM 418
            ::..:.|||.|:|::|.||:..:|:.||..|...|:||:||||..:||||.||:..||::||||:
  Rat   338 IVTPLATAFGTSSSSATLPLMMKCVEEKNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQL 402

  Fly   419 SGMVLGFGELLTVLLTSTAASMSSASVPSAALVLLLVVLTAIDAPVQDVTLLFAVDWFVDRIRTT 483
            :||.|.|.:::|:|:|:||:|:.:|.:|:..::.|.::|.||..||:|::|:.||||.|||..|.
  Rat   403 NGMSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAISLPVKDISLILAVDWLVDRSCTV 467

  Fly   484 NNMLGDCYTAAVVEEL--------SRKELMALDAASVNYQDMPAGTPNGH 525
            .|:.||.:.|.:::..        |..||:.: ...|:.:.:|..|..|:
  Rat   468 LNVEGDAFGAGLLQSYVDRTKMPSSEPELIQV-KNDVSLKPLPLATEEGN 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..499	CDD:425646	159/462 (34%)
Slc1a5	NP_786934.1	GltP	81..477	CDD:440912	151/430 (35%)