Protein Alignment Eaat2 and glt-4

DIOPT Version :9

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_509075.3
• Gene: glt-4 / 188744
• WormBaseID: WBGene00001622
• Length: 499
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 188/537 - (35%)
• Similarity: 302/537 - (56%)
• Gaps: 56/537 - (10%)

  Fly    48 ENLMLLVTLSGVLLGVILGLSLRPLNLHGDS--IMLISYPGELFMRVLKLMILPLVISSLIAGSA 110
            |||:||.|:.||::|:.||.|||..:.....  :..:.:||:||:::||::|||:::||:|...|
 Worm     7 ENLLLLFTVLGVVVGIGLGFSLRDPSKAWSKRHLSYLRFPGDLFVQMLKMLILPMIMSSIITSLA 71

  Fly   111 SLNAKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPGNPDLHNADDR----STDRRAVNLLDS 171
            ||::...|::.:.:::|:..|:||...|||.||.:|.||.....|.:|.    .|.......:|:
 Worm    72 SLDSGTAGRLGMVSMIYYTLTTFFAVFLGIVLVSVIKPGKWTTTNIEDLVGHVKTTPCVATAVDT 136

  Fly   172 LLDLGRNVFPDNLFQASIQQAHTVYLPKPSILHVFNETMN---DTLASGSEAQRLS-EDLTEDVV 232
            ::||.::.||:||.:|:.:.       :...|..||.|..   :...:.|..||.. .::.|.:|
 Worm   137 IIDLMKSCFPENLIEATFRS-------QKICLKFFNGTTEIPPEIAMTMSPEQRAQFTEVPEKIV 194

  Fly   233 LVRDIQYRSGTNTLGIVFFCLVFGTFLGTIGQKGQVVVDFFAAIFEVIMKMVTCVMWLTPVGISS 297
                   ..|.|.||:|.|.:..|..:|.||:.|:.:.:||.::....||::..|:..:||||:.
 Worm   195 -------SDGMNILGLVVFSVALGIVIGVIGEDGKPMKNFFKSLEACSMKLIGWVIIYSPVGITF 252

  Fly   298 VIAGKILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQAIYFVVVRRNPFKFYAGLIQAMLTAF 362
            :||.:|:.:.|.|..:.:||.:::||.:|:.|:.|||:..:..|:.||||.||..|:.||:|||.
 Worm   253 LIAAQIVGMKDPGQELHRLMGYVITVILGLLIHAFVVIPLLCVVLARRNPIKFVGGMAQALLTAL 317

  Fly   363 ATASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNINMDGTALYIAVASIFIAQMSGMVLGFGE 427
            ||:|::|.||::.:|..|..|||||:||||||:|..|||||||||.|||:|:|:|..|..|..||
 Worm   318 ATSSSSATLPLSIKCCEENNKVDPRVTRFVLPLGATINMDGTALYEAVAAIYISQCYGNDLSLGE 382

  Fly   428 LLTVLLTSTAASMSSASVPSAALVLLLVVLTAIDAPVQDVTLLFAVDWFVDRIRTTNNMLGDCYT 492
            ::.|.||:|.||:.:|.:|.|.:|.:::||.||..|.....|:|.||:.:||:|||.|:.||...
 Worm   383 VVLVSLTATLASIGAAGIPQAGIVTMIMVLIAIGLPTNLFILIFPVDFMLDRLRTTVNVHGDSIA 447

  Fly   493 AAVVEELSRKELMALDAASVNYQDMPAGTPNGHGHGHGHHDGGLLEGQTELETSSKCVMTMTDSV 557
            .||:|.|...:|..                      .|||          |:|:.:....::.:.
 Worm   448 TAVIERLCEDQLQK----------------------GGHH----------LDTNDQGYSMLSTNA 480

  Fly   558 VVDISAVMNNVNLQQEH 574
            ..|...:....|.:..|
 Worm   481 SPDPKRITIGNNCENSH 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..496	CDD:278787	173/454 (38%)
glt-4	NP_509075.3	SDF	10..454	CDD:278787	175/457 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100309
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.730