Protein Alignment Eaat2 and glt-5

DIOPT Version :9

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_496094.1
• Gene: glt-5 / 174530
• WormBaseID: WBGene00001623
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 486
• Identity: 197/486 - (40%)
• Similarity: 304/486 - (62%)
• Gaps: 39/486 - (8%)

  Fly    45 WLSENLMLLVTLSGVLLGVILGLSLRPLNLHGDSIMLISYPGELFMRVLKLMILPLVISSLIAGS 109
            ||::|::||:|::|:::|||:|..||..:...|.|..:.:||||||.:||.|:|||:.:|:::|.
 Worm    15 WLTKNMLLLMTMAGIVMGVIIGGVLRTADPSPDVIRYVGFPGELFMNMLKAMVLPLIAASIVSGL 79

  Fly   110 ASLNAKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPGNPDLHN--ADDRSTDRRAVNLLDSL 172
            :.|:.|.:|::..|.::|:|.|:.....|||.:|.:|.||:|.:..  ..|:..:...|:.....
 Worm    80 SQLDGKTSGRLGSRAVMYYAITTTHAVILGIIVVSIIQPGDPTIKQKMGYDKEGEAANVSAAQKF 144

  Fly   173 LDLGRNVFPDNLFQASIQQAHTVYLPKPSILHVFNETMNDTLASGSEAQRLSEDLTEDVVLVRDI 237
            |||.||.||:|:.:|:..|..|.|:             |.|.::|:         |.:|:   ..
 Worm   145 LDLFRNAFPENIMRATFSQVQTNYI-------------NQTHSNGA---------THEVL---HT 184

  Fly   238 QYRSGTNTLGIVFFCLVFGTFLGTIGQKGQVVVDFFAAIFEVIMKMVTCVMWLTPVGISSVIAGK 302
            .|..|.|.|||:.||:|.|..:..||::.:.:.:.|.|:..||.:||..:|||.|:||.|:||.|
 Worm   185 GYVDGMNVLGIIVFCIVMGLVVSRIGEEAKALANLFHALDVVITRMVMLIMWLGPIGIPSLIAQK 249

  Fly   303 ILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQAIYFVVVRRNPFKFYAGLIQAMLTAFATAST 367
            :|.|.||.|....|..|:.||.:|:.|..|:.:..|||:..|.||:.|..||.||::||..|:|:
 Worm   250 MLEVSDLWLTARMLGLFVFTVILGLAIQAFITLPLIYFIGTRHNPYTFLKGLGQAIMTALGTSSS 314

  Fly   368 AAALPITFRCMNEKLKVDPRITRFVLPIGCNINMDGTALYIAVASIFIAQMSGMVLGFGELLTVL 432
            ||:||:||||:| ||.:|||:|:||||:|..:||||||||.|.||||||||:|:.|..|:::||.
 Worm   315 AASLPVTFRCLN-KLGIDPRVTKFVLPVGAMVNMDGTALYEATASIFIAQMNGLELSIGQIVTVS 378

  Fly   433 LTSTAASMSSASVPSAALVLLLVVLTAIDAPVQDVTLLFAVDWFVDRIRTTNNMLGDCYTAAVVE 497
            :|:|.||:.:||:|||.||.:|:||||:..|..|::|:.|||||:||:||:.|::||......|.
 Worm   379 ITATLASIGAASIPSAGLVTMLIVLTALGLPANDISLILAVDWFLDRLRTSVNVIGDALGCGFVH 443

  Fly   498 ELSRKELMA-----------LDAASVNYQDM 517
            .:....|.|           ::|..||:.::
 Worm   444 HICADHLNADVAEAEKNHAVVEAHGVNFDEL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..496	CDD:278787	188/446 (42%)
glt-5	NP_496094.1	SDF	21..442	CDD:278787	188/446 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	392	1.000	Domainoid score	I393
eggNOG	1	0.900	-	-		E1_COG1301
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	406	1.000	Inparanoid score	I1074
Isobase	1	0.950	-	0	Normalized mean entropy	S3077
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	1	1.000	-	-		otm14496
orthoMCL	1	0.900	-	-		OOG6_100309
Panther	1	1.100	-	-	LDO	PTHR11958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X191
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.830