Protein Alignment Eaat2 and slc1a7

DIOPT Version :10

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_004914070.1
• Gene: slc1a7 / 100497134
• XenbaseID: XB-GENE-979919
• Length: 564
• Species: Xenopus tropicalis
• Alignment Length: 558
• Identity: 201/558 - (36%)
• Similarity: 314/558 - (56%)
• Gaps: 50/558 - (8%)

  Fly    49 NLMLLVTLSGVLLGVILGLSLRPLNLHGDSIMLISYPGELFMRVLKLMILPLVISSLIAGSASLN 113
            |.:|::::..|::|.:||..||...|....|....:||||.||:||::|||||:|||::|.|:|:
 Frog    19 NGLLILSVLSVIVGCLLGFFLRTRRLTEQEISYFQFPGELLMRMLKMLILPLVVSSLMSGLAALD 83

  Fly   114 AKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPGNPDLHNADDRSTDRRAVNLLDSLLDLGRN 178
            ||.:.::.:.|:.|:..|:|....:||.:|.:||||........::| .:..::..|:||||.||
 Frog    84 AKTSSRLGIFTIAYYLWTTFVAVIVGIIMVSIIHPGGAAQKETTEQS-GKPVMSSADALLDLIRN 147

  Fly   179 VFPDNLFQASIQQAHTVYLPKPSILHVF-NETMNDTLA-------SGSEAQRLSEDLTEDVVLVR 235
            :||.||.:|:.:|..|..:|.......| :|:....:.       :||..|..:.|:|..    .
 Frog   148 MFPSNLVEATFKQYRTKNVPVMKPARAFPSESFTHRIVIYGIQDENGSHIQNFALDITPS----P 208

  Fly   236 DIQYRS------GTNTLGIVFFCLVFGTFLGTIGQKGQVVVDFFAAIFEVIMKMVTCVMWLTPVG 294
            |:.|:|      |.|.||||.|....|..||.:|..|..:|.|...:.|.:||:|...:|..|.|
 Frog   209 DVIYKSEPGTSEGMNVLGIVIFSATMGIMLGRMGTSGVPLVSFCQCLNESVMKIVAVAVWYFPFG 273

  Fly   295 ISSVIAGKILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQAIYFVVVRRNPFKFYAGLIQAML 359
            |..:||||||.:.|...:..:|.::.:||..|:.::...::..:|.::.::||..|..|::||:|
 Frog   274 IVFLIAGKILEMDDPTAIGKKLGYYAITVLCGLVVHGLFILPLMYLLITKKNPIVFIRGVLQALL 338

  Fly   360 TAFATASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNINMDGTALYIAVASIFIAQMSGMVLG 424
            .|.||:|::|.|||||:|:.|...:|.|:.|||||:|..|||||||||.|||:|||||::...|.
 Frog   339 IALATSSSSATLPITFKCLLENNHIDRRVARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELD 403

  Fly   425 FGELLTVLLTSTAASMSSASVPSAALVLLLVVLTAIDAPVQDVTLLFAVDWFVDRIRTTNNMLGD 489
            ||:::|:.:|:||||:.:|.:|.|.||.:::|||::..|..|:||:.||||.:||.||..|:|||
 Frog   404 FGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGD 468

  Fly   490 CYTAAVVEELSRKELMALDAASVNYQDMP--------------AGTPNGHGHGHG-------HHD 533
            ...|.::..:.||     |.|..|.:.:|              |...||....|.       ..:
 Frog   469 ALAAGIMAHICRK-----DFAKQNDEQVPLICETKPISLHQIMAYQRNGCVKSHSVPQFSPTPQE 528

  Fly   534 GGLLEGQTEL---ETSSKCVMTMTDSVVVDISAVMNNV 568
            ...::...|.   |||.:|  |..|...::||.:..||
 Frog   529 FQQMQEDPESAFPETSERC--TDKDHCTIEISELETNV 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..499	CDD:425646	179/461 (39%)
slc1a7	XP_004914070.1	SDF	21..478	CDD:425646	179/461 (39%)