DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eaat2 and LOC100496635

DIOPT Version :9

Sequence 1:	NP_001162844.1	Gene:	Eaat2 / 33247	FlyBaseID:	FBgn0026438	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_017951228.2	Gene:	LOC100496635 / 100496635	-ID:	-	Length:	557	Species:	Xenopus tropicalis

Alignment Length:	529	Identity:	233/529 - (44%)
Similarity:	344/529 - (65%)	Gaps:	46/529 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GPPTSTELPPK---TTECSDAPVELTGYRRWLSENLMLLVTLSGVLLGVILGLSLRPL-NLHGDS 78
            |...|.|..||   |..||           ||..||:|::|:.|||||.:.|..||.| .|..:.
Frog    12 GHHMSIEDLPKPCWTKRCS-----------WLRRNLLLILTIGGVLLGSLFGCLLRLLPPLDSNI 65

  Fly    79 IMLISYPGELFMRVLKLMILPLVISSLIAGSASLNAKMNGKIALRTLVYFASTSFFNAALGIALV 143
            ::|||:||::.||:||::||||:|||||:|.|.|:||.:|::..|.:||:.||:...|.||:.||
Frog    66 LILISFPGDILMRMLKMLILPLIISSLISGLAGLDAKSSGRMGTRAMVYYMSTTILAAVLGVILV 130

  Fly   144 LLIHPGNPDLHNADDRSTDRRAVNLLDSLLDLGRNVFPDNLFQASIQQAHTV-----------YL 197
            |.||||||.|......|:....|:.:|:.|||.||:||:||.||..||..||           .|
Frog   131 LSIHPGNPKLKKQVSISSKNEEVSSIDAFLDLIRNLFPENLVQACFQQISTVSKKVPVAPSPLEL 195

  Fly   198 PKP-SILHVFNETMNDTLASGSEAQRLSEDLTEDVVLVRDIQYRSGTNTLGIVFFCLVFGTFLGT 261
            .|| :|..:|:   |.:..:.|.|:..:|.|   :|..:.::::||.|.||::.|.:.||..:|.
Frog   196 MKPENISSMFS---NISQPNSSMAEMDTEPL---MVTQKKLEFKSGMNVLGLIGFFIAFGISMGK 254

  Fly   262 IGQKGQVVVDFFAAIFEVIMKMVTCVMWLTPVGISSVIAGKILSVGDLGLVMSQLMWFIVTVAIG 326
            :|::.:::.|||..:.|:||::|..:||.:|:||:|:|.|||..:.||.:|..||..::|||.:|
Frog   255 MGEQAKLMADFFNILNEIIMRLVNMIMWYSPIGIASLICGKIAGIKDLEVVARQLGMYMVTVIVG 319

  Fly   327 VFIYQFVVMQAIYFVVVRRNPFKFYAGLIQAMLTAFATASTAAALPITFRCMNEKLKVDPRITRF 391
            :.|:..:|:..|:|.:.|:|||.||.|:.||.:||..|||:|..||:||||:.|.||:|.|:|||
Frog   320 LVIHGGMVLPLIFFSITRKNPFAFYGGIFQAWITALGTASSAGTLPVTFRCLEENLKIDKRVTRF 384

  Fly   392 VLPIGCNINMDGTALYIAVASIFIAQMSGMVLGFGELLTVLLTSTAASMSSASVPSAALVLLLVV 456
            |||||..|||||||||.|||:||||||:.:.|..|::.||.||:|.||:.:||:|||.||.:|::
Frog   385 VLPIGATINMDGTALYEAVAAIFIAQMNDVSLDGGQIATVSLTATLASVGAASIPSAGLVTMLLI 449

  Fly   457 LTAIDAPVQDVTLLFAVDWFVDRIRTTNNMLGDCYTAAVVEELSRKELMALDAAS---------- 511
            |||:..|.||::||.||||.:||:||:.|::||.:.|.::..||::||.|:||..
Frog   450 LTAVGLPTQDISLLIAVDWLLDRMRTSINVVGDSFGAGIIYHLSKEELAAIDAKHDAKDGADMVK 514

  Fly   512 ---VNYQDM 517
               :|::|:
Frog   515 LQLMNHEDL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..496	CDD:278787	212/457 (46%)
LOC100496635	XP_017951228.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	406	1.000	Domainoid score	I698
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H136399
Inparanoid	1	1.050	429	1.000	Inparanoid score	I1697
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	1	1.000	-	-		otm47952
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X191
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060