Protein Alignment Eaat2 and slc1a2

DIOPT Version :9

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_004913402.1
• Gene: slc1a2 / 100494868
• XenbaseID: XB-GENE-1005169
• Length: 572
• Species: Xenopus tropicalis
• Alignment Length: 524
• Identity: 220/524 - (41%)
• Similarity: 341/524 - (65%)
• Gaps: 36/524 - (6%)

  Fly    49 NLMLLVTLSGVLLGVILGLSLRPLN-LHGDSIMLISYPGELFMRVLKLMILPLVISSLIAGSASL 112
            ||:|.:|:.||::|.:.|..||..: :|.|.:|:|::||::.||:||::||||:|||||.|.|.|
 Frog    48 NLLLSLTVFGVIMGAVSGGLLRMASPIHPDIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGL 112

  Fly   113 NAKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPGNPDLHNADDRSTDRRAVNLLDSLLDLGR 177
            :||.:|::..|.::|:.||:...|.||:.|||.||||:|.|.....:..:...|:.||:.|||.|
 Frog   113 DAKSSGRLGTRAMIYYMSTTIIAAILGVILVLAIHPGDPKLKKQLGKGQENDEVSSLDAFLDLIR 177

  Fly   178 NVFPDNLFQASIQQAHTVYLPKPSILHVFNE-----------TMNDTLASGSEAQRLSEDLTEDV 231
            |:||:||.||..||..||  .|..::....|           .||||:|:.:|..|
 Frog   178 NLFPENLVQACFQQIQTV--TKKVVVEAPTEEPSNVTDSVFALMNDTVATTTEEIR--------- 231

  Fly   232 VLVRDIQYRSGTNTLGIVFFCLVFGTFLGTIGQKGQVVVDFFAAIFEVIMKMVTCVMWLTPVGIS 296
               :.::::.|.|.||::.|.:.||..:|.:|::.:::|:||..:.|::||:||.:||.:|:||:
 Frog   232 ---KKLEFKDGMNVLGVIGFFIAFGIAMGKMGEQARLMVEFFNILNEIVMKLVTMIMWYSPLGIA 293

  Fly   297 SVIAGKILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQAIYFVVVRRNPFKFYAGLIQAMLTA 361
            .:|.|||:::.||.||..||..::|||.:|:.|:..:.:..:|||:.|::||.|.||:.||.:||
 Frog   294 CLICGKIIAIKDLELVARQLGMYMVTVIVGLIIHGAIFLPLLYFVITRKSPFTFLAGVFQAWITA 358

  Fly   362 FATASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNINMDGTALYIAVASIFIAQMSGMVLGFG 426
            ..|||:|..||:||||:.|.|.:|.|:||||||:|..|||||||||.|||:||||||:|::|..|
 Frog   359 LGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGG 423

  Fly   427 ELLTVLLTSTAASMSSASVPSAALVLLLVVLTAIDAPVQDVTLLFAVDWFVDRIRTTNNMLGDCY 491
            :::||.||:|.||:.:||:|||.||.:|::|||:..|.||::||.||||.:||:||:.|::||.:
 Frog   424 QIITVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRMRTSVNVVGDSF 488

  Fly   492 TAAVVEELSRKELMALDAASVNYQDMPAGTPNGHGHGHGHHDGGLLEGQTELETSSKCVMTMTDS 556
            .|.:|..||:.||.:||....:.:.....|.:.:.....|.:          ..|::|:....:|
 Frog   489 GAGIVYHLSKAELESLDKQHAHQEIEMTKTQSIYDDMKNHRE----------NNSNQCIYAAHNS 543

  Fly   557 VVVD 560
            |.||
 Frog   544 VPVD 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..496	CDD:278787	203/456 (45%)
slc1a2	XP_004913402.1	SDF	50..496	CDD:366058	204/459 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	406	1.000	Domainoid score	I698
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	429	1.000	Inparanoid score	I1697
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	1	1.000	-	-		otm47952
Panther	1	1.100	-	-	O	PTHR11958
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X191
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.160