Protein Alignment Eaat2 and slc1a3

DIOPT Version :9

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001106687.1
• Gene: slc1a3 / 100127700
• XenbaseID: XB-GENE-975313
• Length: 542
• Species: Xenopus tropicalis
• Alignment Length: 479
• Identity: 202/479 - (42%)
• Similarity: 312/479 - (65%)
• Gaps: 21/479 - (4%)

  Fly    45 WLSENLMLLVTLSGVLLGVILGLSLRPLNLHGDSIMLISYPGELFMRVLKLMILPLVISSLIAGS 109
            :|..|..:|.|:..|::|:|||.|:|..::....|...|:||||.||:|::::|||::|||:.|.
 Frog    44 FLKRNGFVLFTVFAVIIGIILGFSVRKYHMTFREIKYFSFPGELLMRMLQMLVLPLIVSSLVTGM 108

  Fly   110 ASLNAKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPG---NPDLHNADDRSTDRRAVNLLDS 171
            |:|::|.:||:.:|.:||:.:|:.....:||.:|::||||   ...:|    |......|...|:
 Frog   109 AALDSKASGKMGIRAVVYYMTTTVIAVFIGIIIVIIIHPGKGSKEKMH----REGKIEQVTAADA 169

  Fly   172 LLDLGRNVFPDNLFQASIQQAHTVY------LPKPSILHVFNETMNDTLASG-SEAQRLSEDLTE 229
            .:||.||:||.|:.:|..:|..|.|      :|.|.     ||::..::|:. |||........|
 Frog   170 FMDLIRNMFPPNMVEACFKQFKTNYEKKQFRVPIPE-----NESLLSSVANNVSEAMETLTKFRE 229

  Fly   230 DVVLVRDIQYRSGTNTLGIVFFCLVFGTFLGTIGQKGQVVVDFFAAIFEVIMKMVTCVMWLTPVG 294
            ::|.|....  :|.|.||:|.|.:.||..:|.:.::|:.:.|||.::.|.||::|..:||..|:|
 Frog   230 EIVPVAGSV--NGVNALGLVVFSMCFGLVIGNMKEQGKALKDFFDSLNEAIMRLVAVIMWYAPIG 292

  Fly   295 ISSVIAGKILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQAIYFVVVRRNPFKFYAGLIQAML 359
            |..:|||||..:.|:|:|..||..:.:||.:|:.|:...|:..:||:|.|:||:.|..|||||::
 Frog   293 ILFLIAGKIAEMEDMGVVGGQLGMYTITVIVGLLIHAIFVLPLLYFLVTRKNPWVFIGGLIQALI 357

  Fly   360 TAFATASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNINMDGTALYIAVASIFIAQMSGMVLG 424
            ||..|:|::|.|||||:|:.|...||.|:||||||:|..|||||||||.|:|:|||||::...|.
 Frog   358 TALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNYDLN 422

  Fly   425 FGELLTVLLTSTAASMSSASVPSAALVLLLVVLTAIDAPVQDVTLLFAVDWFVDRIRTTNNMLGD 489
            ||:::|:.:|:||||:.:|.:|.|.||.:::|||::..|.:|:||:.|||||:||:|||.|:|||
 Frog   423 FGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTTTNVLGD 487

  Fly   490 CYTAAVVEELSRKELMALDAASVN 513
            ...|.:||.|||.||...||...|
 Frog   488 SLGAGIVEHLSRHELKRGDAEMGN 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..496	CDD:278787	190/454 (42%)
slc1a3	NP_001106687.1	SDF	50..497	CDD:366058	192/457 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	1	1.000	-	-		otm47952
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X191
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930