Protein Alignment Eaat2 and slc1a4

DIOPT Version :10

• Sequence 1: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001096391.1
• Gene: slc1a4 / 100124992
• XenbaseID: XB-GENE-980499
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 512
• Identity: 182/512 - (35%)
• Similarity: 299/512 - (58%)
• Gaps: 37/512 - (7%)

  Fly     3 MEKSGKFSDYLFAKMGPPTSTELPPKTTECSDAPVE--LTGYR--RWLSENLMLLVTLSGVLLGV 63
            |||..:.:.:: .:....|:.|:..|..|.|....:  ..|:|  ::|.:|.::::|:||||:||
 Frog     1 MEKQSETNGHI-TRYPDGTACEMDDKEPETSSPKKKKAAEGHRCAQFLKKNAIVILTVSGVLVGV 64

  Fly    64 ILGLSLRPLNLHGDSIMLISYPGELFMRVLKLMILPLVISSLIAGSASLNAKMNGKIALRTLVYF 128
            .||.::|.:||....:...::|||:.:|:||::|||||:.|||:|:|||:.:..||:....:.||
 Frog    65 GLGTAVRKMNLTKAQMSYFAFPGEMLLRMLKMIILPLVVCSLISGAASLDTRSLGKLGGIAVAYF 129

  Fly   129 ASTSFFNAALGIALVLLIHPG-------NPDLHNADDRSTDRRAVNLLDSLLDLGRNVFPDNLFQ 186
            ..|:...:.|.|||..:|.||       :.:|...:..||::..|   ||.|||.||:.|.||..
 Frog   130 LVTTLMASGLAIALGFIIKPGAGAGALNSNELGIEEALSTNKETV---DSFLDLARNLMPSNLVA 191

  Fly   187 ASIQQAHTVYLPKPSILHVFNETMNDTLASGSEAQRLSEDLTEDVVLVRDIQYRSGTNTLGIVFF 251
            |:.:...|.|       ..|.:...|.|            :||.|.:..:::   |.|.||:|.|
 Frog   192 AAFRSFATDY-------KTFTKNTTDGL------------ITEKVPIGTEVE---GMNILGLVLF 234

  Fly   252 CLVFGTFLGTIGQKGQVVVDFFAAIFEVIMKMVTCVMWLTPVGISSVIAGKILSVGDLGLVMSQL 316
            .||.|..|..:|.:|:.::.||.|..|..|.:|:.:||..|:||..::..||:.:|::.|:::.|
 Frog   235 ALVLGVALKKLGPEGEELIRFFNAFNEATMVLVSWIMWYVPIGIMFLVGSKIVEMGNIVLLVTSL 299

  Fly   317 MWFIVTVAIGVFIYQFVVMQAIYFVVVRRNPFKFYAGLIQAMLTAFATASTAAALPITFRCMNEK 381
            ..:|:...:|..|:..:|:..|||...|:||:.|..|||....|||||:|::|.||...:|:.|.
 Frog   300 GKYIMASILGHVIHGGIVLPLIYFAFTRKNPYTFLLGLITPFATAFATSSSSATLPTMIKCIEEN 364

  Fly   382 LKVDPRITRFVLPIGCNINMDGTALYIAVASIFIAQMSGMVLGFGELLTVLLTSTAASMSSASVP 446
            ..||.||:||:||||..:||||.|::..:|::|||||:...|..|::.|:|:|:||:|:.:|.:|
 Frog   365 NGVDKRISRFILPIGATVNMDGAAIFQCMAAVFIAQMNSAELNAGQIFTILVTATASSVGAAGIP 429

  Fly   447 SAALVLLLVVLTAIDAPVQDVTLLFAVDWFVDRIRTTNNMLGDCYTAAVVEELSRKE 503
            :..::.:.::|.||..|..|::|:.||||.|||..|..|:.||...|.::..|::||
 Frog   430 AGGVLTIAIILEAIGLPTNDLSLILAVDWIVDRTTTVVNVEGDALGAGILHHLNQKE 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat2	NP_001162844.1	SDF	51..499	CDD:425646	167/454 (37%)
slc1a4	NP_001096391.1	GltP	48..476	CDD:440912	167/452 (37%)