Sequence 1: | NP_001285551.1 | Gene: | ds / 33245 | FlyBaseID: | FBgn0284247 | Length: | 3556 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001278232.1 | Gene: | FAT4 / 79633 | HGNCID: | 23109 | Length: | 4983 | Species: | Homo sapiens |
Alignment Length: | 3897 | Identity: | 1091/3897 - (27%) |
---|---|---|---|
Similarity: | 1689/3897 - (43%) | Gaps: | 816/3897 - (20%) |
- Green bases have known domain annotations that are detailed below.
Fly 51 PSHMLR-SSLLILLAIVLLGSSQAASHDQERERKLEVFE----GVAVDYQIGYIGDFGGIDSGPP 110
Fly 111 YII-VAEAGVETDLAIDRATGEIRTKVKLDRETRAS--YSLVAI---PLSGRNIRVLVTVKDEND 169
Fly 170 NAPTFPQTSMHIEFPENTPREVKRTLLPARDLDL--EPYNTQRYNIVSGNVNDAFRLSSHRERDG 232
Fly 233 V-LYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVP 296
Fly 297 ENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHEL 361
Fly 362 VVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINV-IFLSDDASPKISESAQPGEFVARISVHDPD 425
Fly 426 SKTEYANVNVTLNGGD--GHFAL-TTRDNSIYLVIVHLPLDREIVSNYTLSVVATDK-GTPPLHA 486
Fly 487 SK------SIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAE 545
Fly 546 TPETHAQWFQIDPQTGLITTRSHIDCETEPVPQ--LTVVARDGGVPPLSSTATVLVTIHDVNDNE 608
Fly 609 PIFDQ-SFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIA 672
Fly 673 GELDFERRSSYEFPVLATDRGG--LSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQAS 735
Fly 736 STPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDM-LSVRTQPMHMLNISA 799
Fly 800 TDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRY 864
Fly 865 SIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAP 929
Fly 930 EFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHL 994
Fly 995 DYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVN 1059
Fly 1060 ASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVL 1124
Fly 1125 ATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIR 1189
Fly 1190 YSLLPINSSFQVHPVTGEISTREPLDRE--LRE----LYDLVVEARDQGTP-VRSARVPVRIHVS 1247
Fly 1248 DVNDNAPE-IADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSID 1311
Fly 1312 PTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVRE 1376
Fly 1377 DAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLL 1441
Fly 1442 DREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHN 1506
Fly 1507 FTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQA 1571
Fly 1572 LDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDED 1636
Fly 1637 SGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKS 1701
Fly 1702 SLNLHLIVQG------------------------------------------------------- 1711
Fly 1712 ------------------------------------------------------SHNNPPRFLQA 1722
Fly 1723 VYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRG-IITTRGQFDRES 1786
Fly 1787 QASYVL-------------------------------PVYVRDANRQSTLSSSAVRKQRSSD--- 1817
Fly 1818 --------------------------------------------SIGDTSNGQHFDVATIYITVG 1838
Fly 1839 DVNDNSPEFRPGSCYGLSVPENSEPGVIHTVV---ASDLDEGPNADLIYSITGGN---------- 1890
Fly 1891 ----------------------------------------------------------------- 1890
Fly 1891 ------------------------------LGNKFSIDSSSGELS-ARPLDREQHSRYTLQIQAS 1924
Fly 1925 DRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVY 1989
Fly 1990 SLAN-ETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDN 2053
Fly 2054 RPIFERYPY-------IGQVPALIQPGQTLLKVQALDADLGANAEIVYSL---NAENSAVSAKFR 2108
Fly 2109 INPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRV 2173
Fly 2174 MLKENSPSGTRLLQVVALRSDGRRQKV----------QFSFG----------------------- 2205
Fly 2206 -----AGNEDGILS--------------------------------------------------- 2214
Fly 2215 ---------------LDSLSGEIRVNKP-----------HLLDYDRF-STPSMSALSR--GRALH 2250
Fly 2251 YEEEIDESSEEDPNNSTRSQ--RALTSSSF---------------------ALTN----SQPNEI 2288
Fly 2289 R------VVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAF 2347
Fly 2348 DSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTA 2412
Fly 2413 TIRVQIVDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSI 2477
Fly 2478 -FALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQQPPAYF 2541
Fly 2542 AILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVV--------- 2597
Fly 2598 ------SVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQ 2656
Fly 2657 ISEAAPLGSVVLQLGQDALDQ---------SLAIIAGNEESAFELLQSKA-IVLVKPLDRERNDL 2711
Fly 2712 YKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQL- 2775
Fly 2776 QAIDA-DQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSH-- 2837
Fly 2838 HQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIG 2902
Fly 2903 PAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKK--ASVAVRVEIESRDEF 2965
Fly 2966 TPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQL--SAPHSHFKVNRSSGAVLI 3028
Fly 3029 ----------KRKLKLDGDGDGNLYMDGRDISLV---ISASSGRHNSLSSMAVVEIALDPLAHPG 3080
Fly 3081 TNLASAGGSSSGSIGDWAIGLLVAFLLVLCAAAGIFLFIHMRSRKPRNAVKPHLATDNAGVGNTN 3145
Fly 3146 SYVDPSAFDTIPIRGSISGGAAGAASGQFAPPKYDEIPPFGAHAGS-SGAATTSELSGSEQSGSS 3209
Fly 3210 GRGSAEDDGEDEEIRM----------------INEGPLHHRNGGAGAGSDDGRISDISVQNTQEY 3258
Fly 3259 LAR-------LGIVDHDPSGAGGGASSMAGSSHPMHL----YHDDDATARS-------------- 3298
Fly 3299 -----------DITNLIYAKL-NDVTGAGSEIGSSADDAGTTAGSIGTIGTAITHGHGVMSS 3348 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ds | NP_001285551.1 | CA | 111..172 | CDD:214520 | 21/66 (32%) |
Cadherin_repeat | 178..282 | CDD:206637 | 39/106 (37%) | ||
Cadherin_repeat | 291..389 | CDD:206637 | 41/97 (42%) | ||
Cadherin_repeat | 406..500 | CDD:206637 | 33/103 (32%) | ||
Cadherin_repeat | 509..607 | CDD:206637 | 40/99 (40%) | ||
Cadherin_repeat | 616..711 | CDD:206637 | 35/96 (36%) | ||
Cadherin_repeat | 719..820 | CDD:206637 | 34/101 (34%) | ||
Cadherin_repeat | 832..927 | CDD:206637 | 35/94 (37%) | ||
Cadherin_repeat | 937..1032 | CDD:206637 | 35/94 (37%) | ||
Cadherin_repeat | 1040..1149 | CDD:206637 | 39/108 (36%) | ||
Cadherin_repeat | 1158..1252 | CDD:206637 | 36/100 (36%) | ||
Cadherin_repeat | 1263..1361 | CDD:206637 | 36/97 (37%) | ||
Cadherin_repeat | 1369..1481 | CDD:206637 | 29/111 (26%) | ||
Cadherin_repeat | 1489..1598 | CDD:206637 | 31/108 (29%) | ||
Cadherin_repeat | 1614..1710 | CDD:206637 | 30/95 (32%) | ||
Cadherin_repeat | 1723..1843 | CDD:206637 | 40/198 (20%) | ||
Cadherin_repeat | 1853..1948 | CDD:206637 | 42/203 (21%) | ||
Cadherin_repeat | 1957..2053 | CDD:206637 | 37/96 (39%) | ||
Cadherin_repeat | 2061..2154 | CDD:206637 | 31/102 (30%) | ||
Cadherin_repeat | 2170..2318 | CDD:206637 | 49/298 (16%) | ||
Cadherin_repeat | 2326..2424 | CDD:206637 | 34/97 (35%) | ||
Cadherin_repeat | 2434..2528 | CDD:206637 | 26/94 (28%) | ||
Cadherin_repeat | 2549..2641 | CDD:206637 | 29/106 (27%) | ||
Cadherin_repeat | 2652..2748 | CDD:206637 | 20/105 (19%) | ||
Cadherin_repeat | 2758..2858 | CDD:206637 | 29/103 (28%) | ||
Cadherin_repeat | 2866..2960 | CDD:206637 | 23/95 (24%) | ||
Cadherin_repeat | 2985..3071 | CDD:206637 | 23/100 (23%) | ||
FAT4 | NP_001278232.1 | Cadherin_repeat | 48..131 | CDD:206637 | 26/96 (27%) |
Cadherin_repeat | 139..246 | CDD:206637 | 39/106 (37%) | ||
Cadherin_repeat | 254..349 | CDD:206637 | 41/98 (42%) | ||
Cadherin_repeat | 364..471 | CDD:206637 | 33/106 (31%) | ||
Cadherin_repeat | 479..577 | CDD:206637 | 39/99 (39%) | ||
Cadherin_repeat | 588..685 | CDD:206637 | 35/96 (36%) | ||
Cadherin_repeat | 693..789 | CDD:206637 | 35/104 (34%) | ||
Cadherin_repeat | 798..889 | CDD:206637 | 35/94 (37%) | ||
Cadherin_repeat | 899..992 | CDD:206637 | 35/94 (37%) | ||
Cadherin_repeat | 1000..1096 | CDD:206637 | 39/108 (36%) | ||
Cadherin_repeat | 1105..1206 | CDD:206637 | 36/100 (36%) | ||
Cadherin_repeat | 1215..1311 | CDD:206637 | 36/100 (36%) | ||
Cadherin_repeat | 1321..1416 | CDD:206637 | 28/109 (26%) | ||
Cadherin_repeat | 1428..1525 | CDD:206637 | 30/104 (29%) | ||
Cadherin_repeat | 1540..1622 | CDD:206637 | 30/96 (31%) | ||
Cadherin_repeat | 1634..1736 | CDD:206637 | 0/101 (0%) | ||
Cadherin_repeat | 1747..1837 | CDD:206637 | 26/91 (29%) | ||
Cadherin_repeat | 1845..1940 | CDD:206637 | 13/95 (14%) | ||
Cadherin_repeat | 1948..2047 | CDD:206637 | 17/101 (17%) | ||
Cadherin_repeat | 2057..2150 | CDD:206637 | 26/93 (28%) | ||
Cadherin_repeat | 2159..2254 | CDD:206637 | 36/95 (38%) | ||
Cadherin_repeat | 2263..2360 | CDD:206637 | 31/108 (29%) | ||
Cadherin_repeat | 2369..2464 | CDD:206637 | 15/94 (16%) | ||
Cadherin_repeat | 2472..2559 | CDD:206637 | 10/86 (12%) | ||
Cadherin_repeat | 2573..2667 | CDD:206637 | 22/93 (24%) | ||
Cadherin_repeat | 2675..2771 | CDD:206637 | 34/97 (35%) | ||
Cadherin_repeat | 2778..2870 | CDD:206637 | 26/97 (27%) | ||
Cadherin_repeat | 2878..2981 | CDD:206637 | 32/119 (27%) | ||
Cadherin_repeat | 2990..3085 | CDD:206637 | 19/102 (19%) | ||
Cadherin_repeat | 3095..3192 | CDD:206637 | 29/100 (29%) | ||
Cadherin_repeat | 3201..3295 | CDD:206637 | 23/98 (23%) | ||
Cadherin_repeat | 3305..3402 | CDD:206637 | 26/100 (26%) | ||
Cadherin_repeat | 3410..3508 | CDD:206637 | 25/141 (18%) | ||
Cadherin_repeat | 3516..3612 | CDD:206637 | 18/101 (18%) | ||
EGF_CA | 3864..3900 | CDD:238011 | |||
EGF_CA | 3902..3938 | CDD:238011 | |||
EGF_CA | 3941..3976 | CDD:238011 | |||
LamG | 3979..4142 | CDD:238058 | |||
EGF | 4168..4198 | CDD:278437 | |||
LamG | 4247..4368 | CDD:238058 | |||
EGF_CA | 4431..4465 | CDD:238011 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 1 | 1.000 | 73 | 1.000 | Domainoid score | I9278 |
eggNOG | 1 | 0.900 | - | - | E33208_3B9B2 | |
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D23733at33208 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0001195 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 1 | 0.900 | - | - | OOG6_100175 | |
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
7 | 6.720 |