Sequence 1: | NP_001285551.1 | Gene: | ds / 33245 | FlyBaseID: | FBgn0284247 | Length: | 3556 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_071407.4 | Gene: | CDH23 / 64072 | HGNCID: | 13733 | Length: | 3354 | Species: | Homo sapiens |
Alignment Length: | 3019 | Identity: | 884/3019 - (29%) |
---|---|---|---|
Similarity: | 1350/3019 - (44%) | Gaps: | 397/3019 - (13%) |
- Green bases have known domain annotations that are detailed below.
Fly 185 ENTPREVKRTLLPARDLDLEPYNTQRYNIVSG-NVNDAFRLSSHRERDGVLYLDLQISGFLDRET 248
Fly 249 TPGYSLLIEALDGGTPPLRGFMT--VNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYAS 311
Fly 312 DTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGE-QPLET 375
Fly 376 TAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDS-------------- 426
Fly 427 -----KTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVAT---DKGTPP 483
Fly 484 LHASKSIF-LRITDVNDNPPEFEQDLYHANVMEVADPGTSV---LQVLAHDRDEGLNSALTYSLA 544
Fly 545 ETPETHAQWFQIDPQT--GLITTRSHI----DCETEPVPQLTVVARDGGVPPLSSTATVLVTIHD 603
Fly 604 VNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGE 668
Fly 669 ICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQ 733
Fly 734 ASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIF---RIDRSTGEIFVVRPDMLSVRTQPMHML 795
Fly 796 NISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRS 860
Fly 861 PVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQ------VNI 919
Fly 920 EVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDAR 984
Fly 985 SGHLILSQH--LDYESSQRH------TLIVTATDGGVPSL--STNLTILVDVQDVNDNPPVFEKD 1039
Fly 1040 EYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGW 1104
Fly 1105 IYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRG 1169
Fly 1170 SVVGVVTASDLDLGENAAIRYSLL--PINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQG 1232
Fly 1233 TPV---RSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITY 1294
Fly 1295 SIVKGRDSDGHG-LFSIDPTSGVI-RTRVVLDHEERSIYRLGVAA--SDGGNPPRETVRMLRVEV 1355
Fly 1356 LDLNDNRPTFTSSSLV-FRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTK 1419
Fly 1420 DLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPE 1484
Fly 1485 WPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTG 1549
Fly 1550 ALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTAS 1614
Fly 1615 LFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRI---NSQTGIIELVKSLPPATE 1676
Fly 1677 DVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAV-YRATILENVPSGSFVLQ 1740
Fly 1741 VTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTR-GQFDRESQASYVLPVYVRDANRQST 1804
Fly 1805 LSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIH-- 1867
Fly 1868 --TVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGEL-SARPLDRE-QHSRYTLQIQASDRGQ 1928
Fly 1929 PKSRQGHCNITIF--VEDQNDNAPRFKLSKYTG--SVQEDAPLGTSVVQISAVDADLGVNARLVY 1989
Fly 1990 SLAN-ETQWQFAIDGQSGLITTVGK---LDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDI 2050
Fly 2051 NDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGA 2115
Fly 2116 LSASQSLASESGKLLHLEVVARDKGNPP---QSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKE 2177
Fly 2178 NSPSGTRLL----QVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTP 2238
Fly 2239 SMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLA 2303
Fly 2304 SYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDN 2368
Fly 2369 AFVIEPAFSGIVRT-NIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTF-PPN 2431
Fly 2432 NLVTVSEATELGAVITSISANDVDTYPALTYRL-GAESTVDIENM-----SIFALDRYSGKLVLK 2490
Fly 2491 RRLDYELQQEYE--LDVI--ASDAAHEARTV----LTVRVNDENDNAPVFLAQQPPAYFAILPAI 2547
Fly 2548 SEISESLSVDFDLLTVNATDADSEGNNSKVIY-IIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSS 2611
Fly 2612 G----------------DYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEA 2660
Fly 2661 APLGSVVLQL-GQDALDQSLAII---AGNEESAFELLQSKA-IVLVKPLDRERNDLYKLRLVLSH 2720
Fly 2721 PHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENT 2785
Fly 2786 PNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYE---LIIRACDSHHQRPLCSLQP 2847
Fly 2848 FRLELHDENDNEPKF--PLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESS 2910
Fly 2911 WKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGK---KASVAVRVEIESRDEFTPQFT-- 2970
Fly 2971 ---ERTYRFVLPAAVALPQGYVVGQVT-ATDSDSGPDGRVVYQLSAPHSHFKVN-RSSGAVLIKR 3030
Fly 3031 KLKLDGDGDGNLYMDGRDISLVISASSGR 3059 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ds | NP_001285551.1 | CA | 111..172 | CDD:214520 | |
Cadherin_repeat | 178..282 | CDD:206637 | 30/99 (30%) | ||
Cadherin_repeat | 291..389 | CDD:206637 | 35/98 (36%) | ||
Cadherin_repeat | 406..500 | CDD:206637 | 26/116 (22%) | ||
Cadherin_repeat | 509..607 | CDD:206637 | 28/106 (26%) | ||
Cadherin_repeat | 616..711 | CDD:206637 | 30/94 (32%) | ||
Cadherin_repeat | 719..820 | CDD:206637 | 28/103 (27%) | ||
Cadherin_repeat | 832..927 | CDD:206637 | 32/100 (32%) | ||
Cadherin_repeat | 937..1032 | CDD:206637 | 26/104 (25%) | ||
Cadherin_repeat | 1040..1149 | CDD:206637 | 36/108 (33%) | ||
Cadherin_repeat | 1158..1252 | CDD:206637 | 30/98 (31%) | ||
Cadherin_repeat | 1263..1361 | CDD:206637 | 35/101 (35%) | ||
Cadherin_repeat | 1369..1481 | CDD:206637 | 23/112 (21%) | ||
Cadherin_repeat | 1489..1598 | CDD:206637 | 30/108 (28%) | ||
Cadherin_repeat | 1614..1710 | CDD:206637 | 29/98 (30%) | ||
Cadherin_repeat | 1723..1843 | CDD:206637 | 37/121 (31%) | ||
Cadherin_repeat | 1853..1948 | CDD:206637 | 37/102 (36%) | ||
Cadherin_repeat | 1957..2053 | CDD:206637 | 38/101 (38%) | ||
Cadherin_repeat | 2061..2154 | CDD:206637 | 22/95 (23%) | ||
Cadherin_repeat | 2170..2318 | CDD:206637 | 33/151 (22%) | ||
Cadherin_repeat | 2326..2424 | CDD:206637 | 35/98 (36%) | ||
Cadherin_repeat | 2434..2528 | CDD:206637 | 37/107 (35%) | ||
Cadherin_repeat | 2549..2641 | CDD:206637 | 22/108 (20%) | ||
Cadherin_repeat | 2652..2748 | CDD:206637 | 28/100 (28%) | ||
Cadherin_repeat | 2758..2858 | CDD:206637 | 26/102 (25%) | ||
Cadherin_repeat | 2866..2960 | CDD:206637 | 27/96 (28%) | ||
Cadherin_repeat | 2985..3071 | CDD:206637 | 23/77 (30%) | ||
CDH23 | NP_071407.4 | Cadherin_repeat | 42..128 | CDD:206637 | 30/99 (30%) |
Cadherin_repeat | 136..231 | CDD:206637 | 35/98 (36%) | ||
Cadherin_repeat | 240..344 | CDD:206637 | 27/121 (22%) | ||
Cadherin_repeat | 352..456 | CDD:206637 | 28/107 (26%) | ||
Cadherin_repeat | 465..557 | CDD:206637 | 30/94 (32%) | ||
Cadherin_repeat | 566..667 | CDD:206637 | 29/105 (28%) | ||
Cadherin_repeat | 676..774 | CDD:206637 | 32/100 (32%) | ||
Cadherin_repeat | 782..886 | CDD:206637 | 26/106 (25%) | ||
Cadherin_repeat | 894..990 | CDD:206637 | 35/107 (33%) | ||
Cadherin_repeat | 999..1098 | CDD:206637 | 30/99 (30%) | ||
Cadherin_repeat | 1106..1203 | CDD:206637 | 34/103 (33%) | ||
Cadherin_repeat | 1218..1308 | CDD:206637 | 23/105 (22%) | ||
Cadherin_repeat | 1317..1414 | CDD:206637 | 30/108 (28%) | ||
Cadherin_repeat | 1426..1523 | CDD:206637 | 29/102 (28%) | ||
Cadherin_repeat | 1533..1630 | CDD:206637 | 37/119 (31%) | ||
Cadherin_repeat | 1638..1740 | CDD:206637 | 37/104 (36%) | ||
Cadherin_repeat | 1752..1847 | CDD:206637 | 36/97 (37%) | ||
Cadherin_repeat | 1855..1955 | CDD:206637 | 22/101 (22%) | ||
Cadherin_repeat | 1963..2065 | CDD:206637 | 33/151 (22%) | ||
Cadherin_repeat | 2075..2169 | CDD:206637 | 34/95 (36%) | ||
Cadherin_repeat | 2180..2289 | CDD:206637 | 37/108 (34%) | ||
Cadherin_repeat | 2301..2398 | CDD:206637 | 23/114 (20%) | ||
Cadherin_repeat | 2406..2504 | CDD:206637 | 27/99 (27%) | ||
Cadherin_repeat | 2513..2607 | CDD:206637 | 26/103 (25%) | ||
Cadherin_repeat | 2620..2718 | CDD:206637 | 29/98 (30%) | ||
Cadherin_repeat | 2735..2841 | CDD:206637 | 24/84 (29%) | ||
Cadherin_repeat | 2850..2951 | CDD:206637 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E33208_3B9B2 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S7324 |
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 1 | 0.900 | - | - | OOG6_100175 | |
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.660 |