DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ds and Celsr2

DIOPT Version :9

Sequence 1:	NP_001285551.1	Gene:	ds / 33245	FlyBaseID:	FBgn0284247	Length:	3556	Species:	Drosophila melanogaster
Sequence 2:	NP_059088.2	Gene:	Celsr2 / 53883	MGIID:	1858235	Length:	2919	Species:	Mus musculus

Alignment Length:	3490	Identity:	739/3490 - (21%)
Similarity:	1123/3490 - (32%)	Gaps:	1275/3490 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   493 RITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTY---SLAETPETHAQWF 554
            |..:|| ..|:|:...|.|.|.|....||||..:.|.|.|||....|.|   :|.::...|  :|
Mouse   171 RKRNVN-TAPQFQPPSYQATVPENQPAGTSVASLRAIDPDEGEAGRLEYTMDALFDSRSNH--FF 232

  Fly   555 QIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVS 619
            .:||.||::||...:|.||:......|.|:|.|:|..|:.||:.:.:.|.||::|:|:|..|..|
Mouse   233 SLDPITGVVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKES 297

  Fly   620 VAENEPVGRCILKVSASDPDCGVNAMVNYTI--GEGFKHLTEFEVRSASGEICIAGELDFERRSS 682
            :.||..||..:|.|.|:|.|...||.:.|.:  |.|......||:...||.|...|.:|.|...|
Mouse   298 LRENLEVGYEVLTVRATDGDAPPNANILYRLLEGAGGSPSDAFEIDPRSGVIRTRGPVDREEVES 362

  Fly   683 YEFPVLATDR----GGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRE--SPKASSQASSTPIVA 741
            |:..|.|:|:    |..|:||::.:.:.|.|||.|.|..:.|.|.:||  :|.|       |::.
Mouse   363 YKLTVEASDQGRDPGPRSSTAIVFLSVEDDNDNAPQFSEKRYVVQVREDVTPGA-------PVLR 420

  Fly   742 VVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLR 806
            |.|:|.|.|:...|.|.|::||..|.|.:|..||.:.||.|  |...|...:.|.|.|.|||
Mouse   421 VTASDRDKGSNALVHYSIMSGNARGQFYLDAQTGALDVVSP--LDYETTKEYTLRIRAQDGG--- 480

  Fly   807 SNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDP 871
                            |||:                                      |..||
Mouse   481 ----------------RPPL--------------------------------------SNVSG-- 489

  Fly   872 DGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMV 936
                                                        .|.::|.|:|||||.|.::..
Mouse   490 --------------------------------------------LVTVQVLDINDNAPIFVSTPF 510

  Fly   937 RISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQR 1001
            :.:|.||..||..:....|.|.|:|.:.::.|||........|.|:..:|.:.::..||.|....
Mouse   511 QATVLESVPLGYLVLHVQAIDADAGDNARLEYSLAGVGHDFPFTINNGTGWISVAAELDREEVDF 575

  Fly  1002 HTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTG 1066
            ::..|.|.|.|.|:|:.:.::.|.:.|||||.|.|.:.||:|.::|..::...::.|:|.|.|.
Mouse   576 YSFGVEARDHGTPALTASASVSVTILDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDA- 639

  Fly  1067 NNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTP 1131
             ::.|||:|...   |..|..|.:..|       ..|.:.|..|||.:...:|.|.|.|:| ||.
Mouse   640 -HSVITYQITSG---NTRNRFSITSQS-------GGGLVSLALPLDYKLERQYVLAVTASD-GTR 692

  Fly  1132 AAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPIN 1196
            ...|  :::|.|.|||.:.|.||.|.|...:.|:...|:.|.:::|:|.|.||||.|.|.:....
Mouse   693 QDTA--QIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSI 755

  Fly  1197 SSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPE-IADPQ 1260
            ..|::...||.::|:..||.|.:..|.|.:.|||.|.|.:|....:.|.|:|||||||: :.|..
Mouse   756 PQFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSY 820

  Fly  1261 EDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDH 1325
            :.  ||.|:.||.|.|:::.|.|||.|.|..:.|:...|.|.||.  |.::.|||::||...||.
Mouse   821 QG--SVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGD--FIVESTSGIVRTLRRLDR 881

  Fly  1326 EERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPI 1390
            |..:.|.|...|.|.|.||..|                                         |:
Mouse   882 ENVAQYVLRAYAVDKGMPPART-----------------------------------------PM 905

  Fly  1391 ERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRA 1455
            |
Mouse   906 E---------------------------------------------------------------- 906

  Fly  1456 LDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDL 1520
                           |.:.|.|||||.|.:.||..|:.|.|.:|:|..:...||||.|.|||..:
Mouse   907 ---------------VTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQI 956

  Fly  1521 QYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTS 1585
            .|:::         :.....:|::|..:|.|:....||:|...||:|::||      .:..|.:.
Mouse   957 MYQIV---------EGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQA------TSAPLVSR 1006

  Fly  1586 VTVRLRILDANDHAP----------HFVSPNSS---GGKTASLFISDATRIGEVVAHIVAVDEDS 1637
            .||.:|:||.||:.|          ::|:..||   ||           .||.|.||    |.|.
Mouse  1007 ATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGG-----------AIGRVPAH----DPDI 1056

  Fly  1638 GDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSS 1702
            .|:  |||....||......:|:.||.:.|.::|                    |:.:|.....|
Mouse  1057 SDS--LTYSFERGNELSLVLLNASTGELRLSRAL--------------------DNNRPLEAIMS 1099

  Fly  1703 LNLHLIVQGSHN----------------------------NPPRFL--------QAVYRATILEN 1731
            :   |:..|.|:                            :|.|||        |||  |..|..
Mouse  1100 V---LVSDGVHSVTAQCSLRVTIITDEMLTHSITLRLEDMSPERFLSPLLGLFIQAV--AATLAT 1159

  Fly  1732 VPSGSFVLQVTAKS-LHGAENANLSYEI-----PAGVANDLFHVDWQRGIITTRGQFDRESQASY 1790
            .|....|..|...: ..|....|:|..:     |.|....|...|.|..:...|......| |..
Mouse  1160 PPDHVVVFNVQRDTDAPGGHILNVSLSVGQPPGPGGGPPFLPSEDLQERLYLNRSLLTAIS-AQR 1223

  Fly  1791 VLP----VYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGS 1851
            |||    :.:|:.........|.:|                ||.:..:|.     .:|..|||
Mouse  1224 VLPFDDNICLREPCENYMRCVSVLR----------------FDSSAPFIA-----SSSVLFRP-- 1265

  Fly  1852 CYGLSVPENSEPGVIHTV----------VASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSA 1906
                          ||.|          ...|..| ...||.||...|..|.   ..|..|..:.
Mouse  1266 --------------IHPVGGLRCRCPPGFTGDYCE-TEVDLCYSRPCGPHGR---CRSREGGYTC 1312

  Fly  1907 RPLDREQHSRYTLQIQASDRGQPKSRQGHCN----------ITIFVEDQNDNAPRFKLSKYTGSV 1961
            ..||     .||     .:..:..:..|.|.          :.:.|                |..
Mouse  1313 LCLD-----GYT-----GEHCEASTHSGRCTPGVCKNGGTCVNLLV----------------GGF 1351

  Fly  1962 QEDAPLG----------TSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDR 2016
            :.|.|.|          |......:.....|:..|..::||    ..||...::||:...|:.:.
Mouse  1352 KCDCPSGDFEKPFCQVTTRSFPARSFITFRGLRQRFHFTLA----LSFATKERNGLLLYNGRFNE 1412

  Fly  2017 ELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQ------- 2074
            :    ::|:.|       ||....|.:..:..:.......|        ||..:..||
Mouse  1413 K----HDFVAL-------EVIQEQVQLTFSAGESTTTVSPF--------VPGGVSDGQWHTVQLK 1458

  Fly  2075 ----TLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVV 2135
                .||....|..........|.|::..::.|:.:|      ||:..:.|.|::..:
Mouse  1459 YYNKPLLGQTGLPQGPSEQKVAVVSVDGCDTGVALRF------GAMLGNYSCAAQGTQ------- 1510

  Fly  2136 ARDKGNPPQSSLGLI-ELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVA----LRSDG 2195
                 ...:.||.|. .||:|..|.               |.|:.|  .|:...|.    |:.|.
Mouse  1511 -----GGSKKSLDLTGPLLLGGVPD---------------LPESFP--VRMRHFVGCMKDLQVDS 1553

  Fly  2196 RR-QKVQFSFGAGNEDG-----ILSLDSL--SGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYE 2252
            |. ....|....|...|     |:...|:  :|...||:     ::.||.              |
Mouse  1554 RHIDMADFIANNGTVPGCPTKKIVCDSSICHNGGTCVNQ-----WNAFSC--------------E 1599

  Fly  2253 EEIDESSEEDPNNSTRSQRALTSS-----SFALTNSQPNEIRVVLVARTADAPFL---------- 2302
            ..:....:.........||.|.||     ..:|..|||..:.::...|.||...|
Mouse  1600 CPLGFGGKSCAQEMANPQRFLGSSLVAWHGLSLPISQPWHLSLMFRTRQADGVLLQAVTRGRSTI 1664

  Fly  2303 -----ASYAELVIE----------LEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDS-DA 2351
                 |.:..|.:|          ||....|...:...|.....|.|..        ||..| |.
Mouse  1665 TLQLRAGHVVLSVEGTGLQASSLRLEPGRANDGDWHHAQLALGASGGPG--------HAILSFDY 1721

  Fly  2352 GSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLD----------REIRD-IYKLKIIATDEGV 2405
            |...      .:||      :.|...|:..:||.:.          |..|. :..:::..|.||:
Mouse  1722 GQQK------AEGN------LGPRLHGLHLSNITVGGVPGPASGVARGFRGCLQGVRVSETPEGI 1774

  Fly  2406 PQMTGTATIRVQI------VDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVDTYPALT--- 2461
            ..:..:....:.:      .|..|:.|.  |.|               |..:||.|:|....
Mouse  1775 SSLDPSRGESINVEPGCSWPDPCDSNPC--PTN---------------SYCSNDWDSYSCSCVLG 1822

  Fly  2462 -YRLGAESTVDI---ENMSIF-------------ALDRYSGKLVLKRRLDY-------------- 2495
             |.....:..|:   |:.|:.             .|..|.|. ..:.|:|.
Mouse  1823 YYGDNCTNVCDLNPCEHQSVCTRKPNTPHGYICECLPNYLGP-YCETRIDQPCPRGWWGHPTCGP 1886

  Fly  2496 ---ELQQEYELDVIASDAAHEAR-------------------TVLTVRVNDENDN----APVFLA 2534
               ::.:.::.|...:......:                   |....||.|..|.    .|..:.
Mouse  1887 CNCDVSKGFDPDCNKTSGECHCKENHYRPPGSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIG 1951

  Fly  2535 QQ---------------------------------PPAYFAILPAIS------------------ 2548
            :|                                 |...|. |||.:
Mouse  1952 RQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFG-LPAAAPCPKGSFGTAVRHCDEHR 2015

  Fly  2549 -----EISESLSVDFD-------------------------LLTVNATDADSE--GNNSKVIYII 2581
                 .:....||.|.                         ||..|||...|.  |::.||.|.:
Mouse  2016 GWLPPNLFNCTSVTFSELKGFAERLQRNESGLDSGRSQRLALLLRNATQHTSGYFGSDVKVAYQL 2080

  Fly  2582 -------EPAQEGFSVHPSNGV-VSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQA 2638
                   |.||.||.:..:..| .:.|:.|:                   |...|.::.....:.
Mouse  2081 ATRLLAHESAQRGFGLSATQDVHFTENLLRV-------------------GSALLDAANKRHWEL 2126

  Fly  2639 NDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAIIAGNEESAFELLQSKAIVLVKP 2703
            .....|.:.:|...|.|..|               ||.|::   .....|.|.::....::.|..
Mouse  2127 IQQTEGGTAWLLQHYEAYAS---------------ALAQNM---RHTYLSPFTIVTPNIVISVVR 2173

  Fly  2704 LDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNF---PIFDRSA-KYEA-EIS 2763
            ||:......||          |...:|.......:..|::.....|   |...||| ..|| |..
Mouse  2174 LDKGNFAGTKL----------PRYEALRGERPPDLETTVILPESVFREMPSMVRSAGPGEAQETE 2228

  Fly  2764 ELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYE 2828
            |||.     .|.:..:..|.....|.::|...:|...|                 :||...:|..
Mouse  2229 ELAR-----RQRRHPELSQGEAVASVIIYHTLAGLLPH-----------------NYDPDKRSLR 2271

  Fly  2829 LIIRACDSHHQRPLCSLQPFRLELHDENDNEPKF---PLTEYVHFLAENE---PVGSSVFRAHAS 2887
            :        .:||:.:.....:.:||:.:..|:.   |:|.....|...|   |:  .||
Mouse  2272 V--------PKRPVINTPVVSISVHDDEELLPRALDKPVTVQFRLLETEERTKPI--CVF----- 2321

  Fly  2888 DLDKGPFGQLNYSIGPAPSDESSWK------MFRVDSE-----SGLVTSAFVFDYEQRQRYD--- 2938
                     .|:||  ..|....|.      :||.:|.     :.:.:.|.:.|..:|:..:
Mouse  2322 ---------WNHSI--LVSGTGGWSARGCEVVFRNESHVSCQCNHMTSFAVLMDMSRRENGEILP 2375

  Fly  2939 -------------------------MELLASDMGGKKASVAV----------------------- 2955
                                     :..|.|:..|.:.::..
Mouse  2376 LKTLTYVALGVTLAALMLTFLFLTLLRALRSNQHGIRRNLTAALGLAQLVFLLGINQADLPFACT 2440

  Fly  2956 -------------------------RVEIESRD-EFTPQFTERTY--------RFVLPAAVAL-P 2985
                                     |...|.|| ..:|.   |.|        .|:...||.| |
Mouse  2441 VIAILLHFLYLCTFSWALLEALHLYRALTEVRDVNASPM---RFYYMLGWGVPAFITGLAVGLDP 2502

  Fly  2986 QGYVVGQVTATDSDSGPD-------GRVVYQLSAPHSHFKVNRSSGAVLIKRKLKLDGDGDGNLY 3043
            :||           ..||       ..:::..:.|.: |.|:.|....::..:........|
Mouse  2503 EGY-----------GNPDFCWLSVYDTLIWSFAGPVA-FAVSMSVFLYILSARASCAAQRQG--- 2552

  Fly  3044 MDGRDISLVISASSGRHNSLSSMAVVEIALDPLAHPGTNLASAGGSSSGSIGDWAIGLLVA---- 3104
                      ....|..:.|.|...|.:.|.                    ..|.:.||..
Mouse  2553 ----------FEKKGPVSGLRSSFTVLLLLS--------------------ATWLLALLSVNSDT 2587

  Fly  3105 ----FLLVLC-AAAGIFLFIH--MRSRKPRNAVK----------PHLATDNAGVGNTNSYVDPSA 3152
                :|...| ...|.|:|:.  :.|::.|.|:|          |.|.|.:.   .|:||..||.
Mouse  2588 LLFHYLFAACNCVQGPFIFLSYVVLSKEVRKALKFACSRKPSPDPALTTKST---LTSSYNCPSP 2649

  Fly  3153 FDTIPI---RGSISGGAAGAASGQFAPPKY-------------DEIPP-FGAHAG--SSGAA--- 3195
            :....:   .|..:|....|:....:.|.|             .::|| .|..:|  ..|.|
Mouse  2650 YADGRLYQPYGDSAGSLHSASRSGKSQPSYIPFLLREESTLNPGQVPPGLGDPSGLFLEGQAQQH 2714

  Fly  3196 -----TTSELS-GSEQSGSSGRGSAEDDGEDEE----------IRMINEG----PLHH--RNGGA 3238
                 :.|:|| ..:||||.....:.|..|:||          ..::..|    |||.  ::||.
Mouse  2715 DPDTDSDSDLSLEDDQSGSYASTHSSDSEEEEEEAAFPGEQGWDSLLGPGAERLPLHSTPKDGGP 2779

  Fly  3239 GAGSDDGRISDISVQNTQEYLARLGIVDHDPSGAGGGASSMAGSSHPMHLYHDDDATARSDITNL 3303
            |:|.             ..:|...|....:.||:|           |:
Mouse  2780 GSGK-------------VPWLGDFGTTTKENSGSG-----------PL----------------- 2803

  Fly  3304 IYAKLNDVTGAGSEIGSSADDAGTTAGSIGTIGTAITHGHGVMSSYGEVPVPVPVVVGGSNVGGS 3368
                        .|......||.|..||:|                     |:|
Mouse  2804 ------------EERPRENGDALTREGSLG---------------------PLP----------- 2824

  Fly  3369 LSSIVHSEEELTGSYNWDYLLDWGPQYQPLAHVFSEIARLKDDTLSEHS---------GSGASSS 3424
                                   ||..||...:..:...   .|:||.|         |:|:|..
Mouse  2825 -----------------------GPSTQPHKGILKKKCL---PTISEKSSLLRLPLEQGTGSSRG 2863

  Fly  3425 AKSKHSSSHSSAGAGSVVLKPPPSAPPTHIPPPLLTNVAPRAINL 3469
            :.....|.|.          |||..||.......|..|.|.|:::
Mouse  2864 SSISEGSRHG----------PPPRPPPRQSLQEQLNGVMPVAMSI 2898

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ds	NP_001285551.1	CA	111..172	CDD:214520
		Cadherin_repeat	178..282	CDD:206637
		Cadherin_repeat	291..389	CDD:206637
		Cadherin_repeat	406..500	CDD:206637	3/6 (50%)
		Cadherin_repeat	509..607	CDD:206637	37/100 (37%)
		Cadherin_repeat	616..711	CDD:206637	35/100 (35%)
		Cadherin_repeat	719..820	CDD:206637	33/102 (32%)
		Cadherin_repeat	832..927	CDD:206637	7/94 (7%)
		Cadherin_repeat	937..1032	CDD:206637	28/94 (30%)
		Cadherin_repeat	1040..1149	CDD:206637	34/108 (31%)
		Cadherin_repeat	1158..1252	CDD:206637	33/93 (35%)
		Cadherin_repeat	1263..1361	CDD:206637	35/97 (36%)
		Cadherin_repeat	1369..1481	CDD:206637	7/111 (6%)
		Cadherin_repeat	1489..1598	CDD:206637	33/108 (31%)
		Cadherin_repeat	1614..1710	CDD:206637	22/95 (23%)
		Cadherin_repeat	1723..1843	CDD:206637	26/129 (20%)
		Cadherin_repeat	1853..1948	CDD:206637	20/114 (18%)
		Cadherin_repeat	1957..2053	CDD:206637	19/105 (18%)
		Cadherin_repeat	2061..2154	CDD:206637	19/104 (18%)
		Cadherin_repeat	2170..2318	CDD:206637	37/189 (20%)
		Cadherin_repeat	2326..2424	CDD:206637	20/115 (17%)
		Cadherin_repeat	2434..2528	CDD:206637	19/149 (13%)
		Cadherin_repeat	2549..2641	CDD:206637	23/126 (18%)
		Cadherin_repeat	2652..2748	CDD:206637	16/95 (17%)
		Cadherin_repeat	2758..2858	CDD:206637	19/100 (19%)
		Cadherin_repeat	2866..2960	CDD:206637	20/183 (11%)
		Cadherin_repeat	2985..3071	CDD:206637	14/92 (15%)
Celsr2	NP_059088.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	156..194		9/23 (39%)
		Cadherin_repeat	185..285	CDD:206637	37/101 (37%)
		Cadherin_repeat	293..395	CDD:206637	35/101 (35%)
		Cadherin_repeat	404..501	CDD:206637	43/208 (21%)
		Cadherin_repeat	509..606	CDD:206637	28/96 (29%)
		Cadherin_repeat	614..708	CDD:206637	34/108 (31%)
		Cadherin_repeat	716..811	CDD:206637	33/94 (35%)
		Cadherin_repeat	819..917	CDD:206637	42/221 (19%)
		Cadherin_repeat	925..1019	CDD:206637	33/108 (31%)
		Cadherin_repeat	1042..1120	CDD:206637	26/117 (22%)
		EGF_CA	1289..1324	CDD:238011	12/47 (26%)
		EGF_CA	1333..1366	CDD:238011	5/48 (10%)
		LamG	1369..1552	CDD:238058	44/240 (18%)
		EGF_CA	1578..1609	CDD:238011	7/49 (14%)
		LamG	1618..1767	CDD:238058	34/168 (20%)
		EGF_CA	1795..1829	CDD:238011	11/50 (22%)
		EGF_CA	1826..1867	CDD:238011	6/41 (15%)
		Laminin_EGF	<1850..1889	CDD:333801	5/39 (13%)
		EGF_Lam	1924..1969	CDD:214543	7/44 (16%)
		HormR	1972..2034	CDD:214468	8/62 (13%)
		GAIN	2051..2289	CDD:339749	60/314 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2216..2241		10/29 (34%)
		GPS	2315..2368	CDD:197639	13/70 (19%)
		7tm_GPCRs	2373..2626	CDD:355774	41/300 (14%)
		TM helix 1	2376..2400	CDD:341315	0/23 (0%)
		TM helix 2	2409..2430	CDD:341315	1/20 (5%)
		TM helix 3	2440..2462	CDD:341315	0/21 (0%)
		TM helix 4	2481..2497	CDD:341315	2/15 (13%)
		TM helix 5	2516..2539	CDD:341315	4/23 (17%)
		TM helix 6	2559..2584	CDD:341315	7/44 (16%)
		TM helix 7	2588..2613	CDD:341315	5/24 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2690..2884		58/314 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910