DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ds and Dchs1

DIOPT Version :9

Sequence 1:	NP_001285551.1	Gene:	ds / 33245	FlyBaseID:	FBgn0284247	Length:	3556	Species:	Drosophila melanogaster
Sequence 2:	XP_006507718.1	Gene:	Dchs1 / 233651	MGIID:	2685011	Length:	3431	Species:	Mus musculus

Alignment Length:	3637	Identity:	1260/3637 - (34%)
Similarity:	1799/3637 - (49%)	Gaps:	487/3637 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TFTGNHESKDFAIFHRCRRRSNIKSLYSPPALHPSHMLRSSLLILLAIVLLGS-SQAASHDQERE 81
            ::||....|:.::...|....::::|.             .||:||...:.|| .||.|.|
Mouse   135 SWTGPAMQKELSVALSCPGMKSLRTLL-------------PLLVLLGATVPGSWGQAGSLD---- 182

  Fly    82 RKLEVFEGVAVDYQIGYIGDFGGIDSG----PPYIIVAE--AGVETDLAIDRATGEIRTKVKLDR 140
              |::.|.......||.|.  .|:..|    |.|.|.|:  :||.||||||..:|.:||...|||
Mouse   183 --LQIDEEQPAGTLIGDIS--AGLPPGTAPPPMYFISAQEGSGVGTDLAIDEHSGVVRTARVLDR 243

  Fly   141 ETRASYSLVAIPLSGRNIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEP 205
            |.|..|...|:...|..:.|.|.|.|.||:||.|||....::.||:|....:..|.||||.|...
Mouse   244 ERRDRYRFTAVTPDGATVEVTVRVADINDHAPAFPQARAALQIPEHTALGTRYPLEPARDADAGR 308

  Fly   206 YNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFM 270
            ..||.|.:......:.|||.:.....|....:|.|:|.||||....|.|.:||.|||:||.|...
Mouse   309 LGTQGYALSGDGAGETFRLETRPGPGGAPVPELVIAGELDRENRSHYMLQLEAYDGGSPPRRAQA 373

  Fly   271 TVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQM 335
            .:::|:.|:||:.|.||||||.|.|.|:...|:.||||:|||.||..||.|.|.||||||:.:..
Mouse   374 LLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADAGANGAVTYEINRRQSEGDGP 438

  Fly   336 FRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSD 400
            |.||..||.:.:.:.||||.:.:|||||.|:|.|..|...:|||::.|.|.|||||::.|||||.
Mouse   439 FSIDAHTGFLRLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSA 503

  Fly   401 DASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDRE 465
            |.||::||:|.||:.||||||.|||. .::|:|||:|.||:|||||:|:|:.||||.|...||||
Mouse   504 DGSPRVSEAAPPGQLVARISVSDPDD-GDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDRE 567

  Fly   466 IVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVM-EVADPGTSVLQVLAH 529
            ....|.|.|.|||.|:|||.|..:..|.:||||||.|.|::.||....: |||.||:.|::|.|.
Mouse   568 ERDVYNLRVTATDSGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTAR 632

  Fly   530 DRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSST 594
            |.|:|.|..:|||||  |.||..||.|||.:|:|||.:.:|.|.||.|||.|||.|||:|||.|:
Mouse   633 DPDQGTNGQITYSLA--PGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSS 695

  Fly   595 ATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGF--KHL 657
            |||.|.:.|||||||.|.::|||.|:.|....|.|.|:|:|:|.|.|...:::|::|.|.  ...
Mouse   696 ATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGASGS 760

  Fly   658 TEFEVRSASGEICIAGELDFER-RSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYK 721
            ..|.:.:.||::|....||.:: .||::|.|.|.|.|||.:...:|:.:.|.|||.|.||||||.
Mouse   761 PPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAIDGGGLKSMVYVKVFVADENDNPPQFYPREYA 825

  Fly   722 VSLRESPKASSQASSTPIVAVV---ATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPD 783
            .||        .|.|||..||:   |.|||.|..|::||.|:|||...:|.:|..:|.:.|..|
Mouse   826 ASL--------SAQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWP- 881

  Fly   784 MLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGS 848
             |..|...:..|.|.|.|||.|::...|.|.:||:.....|||||:.:|.:.|.||:..||.||
Mouse   882 -LGRRANSVVQLEIGAQDGGGLQAEPIARVNISIVPGTPTPPIFEQLQYVFSVPEDVAPGTSVG- 944

  Fly   849 VIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVL-LNIQATLGEPPVY 912
            :|.|........||..::..|||.|.||:::.||.::..:|||.|....|| |.::|..|.|||:
Mouse   945 IIQAHNPPGRLGPVTLTLSGGDPRGLFSLDSPSGLLKTLRPLDRELLGPVLELEVRAGSGTPPVF 1009

  Fly   913 GHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKG 977
            ...::.:.::|||||:|.|.|....:.:|::...|.|:|...|.|.|||::.::|::|: ..|.|
Mouse  1010 AVARIRVLLDDVNDNSPAFPAPEDTVLLPQNTAPGTPIYTLRALDPDSGANSRITFNLL-AGGDG 1073

  Fly   978 LFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQD--VNDNPPVFEKDE 1040
            ||.:|..:||:.|...|.......|.|.|.|.|||.|..:::..:.|.:||  ::...|.|:...
Mouse  1074 LFTVDPTTGHVRLMGPLGPPGGPAHELEVEARDGGSPPRTSHFRLRVVIQDLGIHGLAPRFDSPT 1138

  Fly  1041 YSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWI 1105
            |.|::....:...||:||.|...|   .:.:||.:...|            .|..||:...|||:
Mouse  1139 YRVDLPSGTTTGTQILQVQAQAPD---GSPVTYHLAADG------------ASSPFGLESQSGWL 1188

  Fly  1106 YLRAPLDRETRDRYQLTVLATDN-----GTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEEN 1165
            ::|..||||:::.|.|.|:|...     |.....|..|||  :|:.||:.|:..:......:.||
Mouse  1189 WVRTALDRESQELYTLKVMAVSGSKAELGQQTGTATVRVI--ILNQNDHSPRLSEEPTFLAVAEN 1251

  Fly  1166 LRRGSVVGVVTASDLDLGENAAIRYSLLPI---NSSFQVHPVTGEISTREPLDRELRELYDLVVE 1227
            ...|:.||.|.|:|.|.|.|..:.|||..:   :.:|::||.|||::|.:.||||.:..:.|:|:
Mouse  1252 QPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSFQLLVQ 1316

  Fly  1228 ARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDV-----VSVREEQPPGTEVVRVRAVDRDHG 1287
            .:|.|:|.|||...|.:.|.|:|||:|.........     :.|.:..||||.|..::|.|.|.|
Mouse  1317 VQDGGSPPRSATGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEG 1381

  Fly  1288 QNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLR 1352
            :|.:|.|::.    ..|..|||:.|.:|.:.|...|...||..|.|.::|.|.|:|||.....|.
Mouse  1382 ENGTILYTLT----GPGSELFSLHPHTGELHTAASLVRAERPHYVLTLSAHDQGSPPRSASLQLL 1442

  Fly  1353 VEVL---------DL--NDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFE 1406
            |:||         ||  .|:..| ....|.....|....|.::||::| :.||.|   .|
Mouse  1443 VQVLPSTRVVESPDLIEADSAAT-VPVVLTVTAAEGLRPGSLLGSVAP-QEPASV---GV----- 1497

  Fly  1407 DLRVTYTL----NPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFR-LEIRALDTTASNNPQS 1466
               :||||    :|      |..|.:|..||.|.:||.||.|....:| |.:||   .......:
Mouse  1498 ---LTYTLVGGADP------EGTFALDSASGRLYLARPLDFEAGPAWRALTVRA---EGPGGAGA 1550

  Fly  1467 SAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDAD-TGTNGDLQYRLIRYFPQ 1530
            ..:.|::.|.|.|::||.:.:||:.|.:.|....|..::.|.|:||| .|.|.:::|||:|
Mouse  1551 RLLRVQVRVQDENEHAPTFARDPLALALPENPDPGATLYTFRASDADGPGPNSEVRYRLLR---- 1611

  Fly  1531 LNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDA 1595
                ||..:...|:|:.|||||....||.|.....||:|:|.|:.:|.:.|....|:.|:.:.|.
Mouse  1612 ----QEPPVPALRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRAARVSARVFVTDE 1672

  Fly  1596 NDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINS 1660
            ||:||.|.||       :.:.:.:....|....|:||.|.|.|:..:::|.:..| |:|.||:::
Mouse  1673 NDNAPVFASP-------SRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAG-GDGHFRLHA 1729

  Fly  1661 QTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYR 1725
            .||.:.:|:.|     |.|:.....|.:.|.|||.| |:.|:..|.:.|...::..|.|.|..|.
Mouse  1730 TTGALSVVRPL-----DREQRAEHVLTVVALDHGSP-PRSSTQLLTVSVVDVNDEAPAFPQQEYN 1788

  Fly  1726 ATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASY 1790
            ..:.||.|.|:.:|.:.|.......|..::|   .||:.:.|.:|...|::||....|||.|...
Mouse  1789 VILRENSPPGTSLLTLKATDPDLGANGQVTY---GGVSGESFSLDPNTGVLTTLRALDREEQEEI 1850

  Fly  1791 VLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCY-G 1854
            .|.||.||......|:...||                       :||.|.||::|.|  |:.: .
Mouse  1851 YLTVYARDRGLPPLLTHITVR-----------------------VTVEDENDHTPTF--GNTHLS 1890

  Fly  1855 LSVPENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGEL-SARPLDREQHSRYT 1918
            |.|||..:|..:.|:.|||.|.|.|..|.|.|..|:....|::|.:|||. :.||||||....:.
Mouse  1891 LEVPEGQDPQTLTTLRASDPDGGLNGQLQYRILDGDSSGAFALDLTSGEFGTMRPLDREVEPAFQ 1955

  Fly  1919 LQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGV 1983
            |||:|.|.||| :......:|:.|.|.||:||.|.:..|:..|.||||:||.::|:.|.|.|.|.
Mouse  1956 LQIEARDGGQP-ALSATLLVTVTVLDANDHAPVFPVPSYSVEVPEDAPVGTLLLQLQAHDPDDGD 2019

  Fly  1984 NARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVL 2048
            |.|::|.|...|...|.::..||.::|...||||..|||.|.|.|.||......|.|||:.|.|.
Mouse  2020 NGRVMYYLGAGTAGAFLLEPTSGELSTATALDREHCASYAFSVTAVDGAAAGPLSTTVPITITVR 2084

  Fly  2049 DINDNRPIFE------RYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKF 2107
            |:||:.|.|.      |.|..|  |:|.:|...|..::|.|.|.||||.|:|.|.......:.
Mouse  2085 DVNDHAPAFPTSPLRLRLPRPG--PSLNKPTLALATLRAEDRDAGANASILYRLAGTPPPGTT-- 2145

  Fly  2108 RINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYR 2172
             ::..||.:..::|..:...:...|.:||.|.|.|.:|:.|::.:.|...|:..|  ||...:..
Mouse  2146 -VDSYTGEIRVARSPVALGPQDRVLFIVATDLGRPARSATGVVVVGIQGEPERGP--RFPRTSSE 2207

  Fly  2173 VMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFST 2237
            .:|:||:|.||.::...|:.|.|....:.:|..:|||.||.|:...:|.|.|.....||:
Mouse  2208 AVLRENAPPGTPVISPKAVHSGGSNGPITYSILSGNERGIFSIQPSTGAITVRSAEGLDF----- 2267

  Fly  2238 PSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFL 2302
                                  |..|                       .:|:||.|.:..|
Mouse  2268 ----------------------ETSP-----------------------RLRLVLQAESGGA--- 2284

  Fly  2303 ASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHD 2367
            .:::.|.:.|:|.|||:|:|.:..:||.:.|.......:.||.|.|.|.||..::.|.:......
Mouse  2285 FAFSVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPA 2349

  Fly  2368 NA-FVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPN 2431
            .. |.::|| :|.:.|..:|||||....:|.::|||.|.|.:.|:||:.|.::|.|||:||.|..
Mouse  2350 RGLFHVDPA-TGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRPTIPQP 2413

  Fly  2432 NLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYE 2496
            ..:.|||...||:.|..::.||||:.|.|.|.|......|     .|::.||.|::.|...||:|
Mouse  2414 WELRVSEDALLGSEIAQVTGNDVDSGPVLWYVLSPSGPQD-----PFSIGRYGGRVSLTGPLDFE 2473

  Fly  2497 LQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVF---------LAQQPPAYFAILPAISEISE 2552
            ....|.|.::|.|..||....|||.|.|.|||.|.|         |...||.
Mouse  2474 QCDHYHLQLLAHDGPHEGHANLTVLVEDVNDNVPTFSQSLYQVMMLEHTPPG------------- 2525

  Fly  2553 SLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVR 2617
                 ..:|:|:|||.|| |.|..:.|.:....|||.|.|:||.:...:..:  |:...|...|.
Mouse  2526 -----SAILSVSATDRDS-GANGHISYHLASPAEGFRVDPNNGTLFTTVGAM--ALGHEGPGVVD 2582

  Fly  2618 II--AKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQS-- 2678
            ::  |:|.|.|...:...:.||..|.......|....||..:||..|.||.:|.|.....|.|
Mouse  2583 VVLEARDHGAPGRTAQATVHVQLKDQNDHAPSFTLPHYRVAVSEDLPPGSTLLTLEATDADGSRT 2647

  Fly  2679 -----LAIIAGNEESAFELLQSKA---------------IVLVKPLDRERNDLYKLRLVLSHPHG 2723
                 .:||:||....|:|....|               :||::|||.|....|.|.:..:....
Mouse  2648 HATVDYSIISGNRGRVFQLEPRLAEVGDGVGPGPQALGCLVLLEPLDFESLTQYNLTVAAADRGQ 2712

  Fly  2724 PPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNS 2788
            ||      .||.:.|.:|:||.|||.|:|.| |.|...:.|..|:...:..::|.|||.  .|:.
Mouse  2713 PP------RSSAVPVTVTVLDVNDNPPVFTR-ASYRVTVPEDMPVGAELLHVEASDADP--GPHG 2768

  Fly  2789 EVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACD---SHHQRPLCSLQPFRL 2850
            .|.:.::||:...:|.:|..:|.|.::..||.::.|: ::|:::|.|   :|.     ||.|..:
Mouse  2769 LVHFTLSSGDPLGLFELDENSGALRLSRPLDCETQAQ-HQLVVQAADPAGTHF-----SLVPVTV 2827

  Fly  2851 ELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFR 2915
            |:.|.||:.|.|||:.....||||:|.|:.|...||.|.|.|.||:|.||:..|.......:.|.
Mouse  2828 EVQDVNDHGPAFPLSLLSTSLAENQPPGTLVTTLHAIDGDAGTFGRLRYSLLEAVPGPEGREAFS 2892

  Fly  2916 VDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPA 2980
            ::|.:|.:.:...||||....:.:.:.|:|.|...|||.|.|.|...||:.|.|...::.|.:|.
Mouse  2893 LNSSTGELRARVPFDYEHTGSFRLLVGAADAGNLSASVTVSVLITGEDEYDPVFLAPSFHFQVPE 2957

  Fly  2981 AVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSHFKVNRSSGAVLIKRKLKLDGDGDGNLYMD 3045
            ..  .:|:.:|.|.|||.|.|.||.|:|.|:....:|.:|:::||:.::...:..|.|.......
Mouse  2958 GA--QRGHSLGHVQATDEDGGADGLVLYSLATSSPYFGINQTTGALYLRVDSRAPGSGTTTSGGG 3020

  Fly  3046 G-------RDISLVISASSGRHNSLSSMAVVEIALDPLAH------PGTNLASAGGSSSGSIGDW 3097
            |       |::.|.:.|......|.|  |.|.:.:| :.|      |..||...|
Mouse  3021 GRTRREAPRELRLEVVARGPLPGSRS--ATVPVTVD-ITHTALGLAPDLNLLLVG---------- 3072

  Fly  3098 AIGLLVAFLLVLCAAAGIFLFIHMRSRKPRNAVKPHLATDNAGVGNTNSYVDPSAFDTIPIRGSI 3162
            |:...:..::||..||.:...:..||||...|..|            .|...|.|..::...|.
Mouse  3073 AVAASLGVVVVLALAALVLGLVRARSRKAEAAPGP------------MSQTAPIASSSLQKLGR- 3124

  Fly  3163 SGGAAGAASGQFAPPKYDEIPPFGAHA--------GSSGAATTSELSGS-EQSGSSGRGSAEDDG 3218
                        .||.    ||...|.        |..||.......|| :.|.|||||||| ..
Mouse  3125 ------------EPPS----PPPSEHLYHQTLPSYGGPGAGGPYPRGGSLDPSHSSGRGSAE-AA 3172

  Fly  3219 EDEEIRMINEGPLHHRNGGAGAGSDDGRISDISVQNTQEYLARLGIVDHDPSGAGGGASSMAGSS 3283
            ||:|||||||.|               |::.:                         |||:|...
Mouse  3173 EDDEIRMINEFP---------------RVASV-------------------------ASSLAARG 3197

  Fly  3284 HPMHLYHDDDATARSDITNLIYAKLNDVTGAGSEIGSSADDAGTT----AGSIGTIGTAITHGHG 3344
            ....:..|.|..:.:...    ....|....|.:.|.....||.|    .|...| .||...|.|
Mouse  3198 PDSGIQQDADGLSDTSCE----PPAPDTWYKGRKAGLLLPGAGATLYREEGPPAT-ATAFLGGCG 3257

  Fly  3345 VM-SSYGEVPVPVPVVVGGSNVGGSLSSIVHSEEELTGSYNWDYLLDWGPQYQPLAHVFSEIARL 3408
            :. :..|:...|..   |...|.|:|::||..||||.|||||||||.|.||:||||.||:|||||
Mouse  3258 LSPAPAGDYGFPAD---GKPCVAGALTAIVAGEEELRGSYNWDYLLSWCPQFQPLASVFTEIARL 3319

  Fly  3409 KDDTLSEHSGSGASSSAKSKHSSSHSSAGAGSVVLKPPPSAPPTHIPPPLLTNVA-PRAINLPMR 3472
            ||:.                               :|.|.||... ||||:|.|| |.|.::|.:
Mouse  3320 KDEA-------------------------------RPCPPAPRID-PPPLITAVAHPGAKSVPPK 3352

  Fly  3473 LPPHLSLAPAHLP----RSPIGHEASGSFSTSSAMSPSFSPSLSPLATRSPSISPLGA--GP 3528
             |...::|.|..|    ||||.||  ||.| |:||||||||||||||.|||.:||.|.  ||
Mouse  3353 -PASTAVARAIFPPASHRSPISHE--GSLS-SAAMSPSFSPSLSPLAARSPVVSPFGVAQGP 3410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ds	NP_001285551.1	CA	111..172	CDD:214520	28/62 (45%)
		Cadherin_repeat	178..282	CDD:206637	36/103 (35%)
		Cadherin_repeat	291..389	CDD:206637	48/97 (49%)
		Cadherin_repeat	406..500	CDD:206637	53/93 (57%)
		Cadherin_repeat	509..607	CDD:206637	54/98 (55%)
		Cadherin_repeat	616..711	CDD:206637	33/97 (34%)
		Cadherin_repeat	719..820	CDD:206637	40/103 (39%)
		Cadherin_repeat	832..927	CDD:206637	35/95 (37%)
		Cadherin_repeat	937..1032	CDD:206637	31/96 (32%)
		Cadherin_repeat	1040..1149	CDD:206637	33/113 (29%)
		Cadherin_repeat	1158..1252	CDD:206637	37/96 (39%)
		Cadherin_repeat	1263..1361	CDD:206637	37/113 (33%)
		Cadherin_repeat	1369..1481	CDD:206637	34/116 (29%)
		Cadherin_repeat	1489..1598	CDD:206637	38/109 (35%)
		Cadherin_repeat	1614..1710	CDD:206637	28/95 (29%)
		Cadherin_repeat	1723..1843	CDD:206637	32/119 (27%)
		Cadherin_repeat	1853..1948	CDD:206637	39/96 (41%)
		Cadherin_repeat	1957..2053	CDD:206637	42/95 (44%)
		Cadherin_repeat	2061..2154	CDD:206637	27/92 (29%)
		Cadherin_repeat	2170..2318	CDD:206637	32/147 (22%)
		Cadherin_repeat	2326..2424	CDD:206637	33/98 (34%)
		Cadherin_repeat	2434..2528	CDD:206637	35/93 (38%)
		Cadherin_repeat	2549..2641	CDD:206637	26/93 (28%)
		Cadherin_repeat	2652..2748	CDD:206637	35/117 (30%)
		Cadherin_repeat	2758..2858	CDD:206637	28/102 (27%)
		Cadherin_repeat	2866..2960	CDD:206637	33/93 (35%)
		Cadherin_repeat	2985..3071	CDD:206637	27/92 (29%)
Dchs1	XP_006507718.1	Cadherin_repeat	183..273	CDD:206637	35/91 (38%)
		Cadherin_repeat	284..385	CDD:206637	36/100 (36%)
		Cadherin_repeat	394..492	CDD:206637	48/97 (49%)
		Cadherin_repeat	508..602	CDD:206637	53/94 (56%)
		Cadherin_repeat	616..708	CDD:206637	53/93 (57%)
		Cadherin_repeat	717..815	CDD:206637	33/97 (34%)
		Cadherin_repeat	823..915	CDD:206637	39/101 (39%)
		Cadherin_repeat	928..1024	CDD:206637	35/96 (36%)
		Cadherin_repeat	1034..1124	CDD:206637	29/90 (32%)
		Cadherin_repeat	1138..1235	CDD:206637	33/113 (29%)
		Cadherin_repeat	1248..1341	CDD:206637	37/92 (40%)
		Cadherin_repeat	1358..1446	CDD:206637	33/91 (36%)
		Cadherin_repeat	1469..1565	CDD:206637	34/116 (29%)
		Cadherin_repeat	1578..1675	CDD:206637	36/104 (35%)
		Cadherin_repeat	1684..1777	CDD:206637	29/99 (29%)
		Cadherin_repeat	1786..1880	CDD:206637	32/119 (27%)
		Cadherin_repeat	1890..1984	CDD:206637	39/94 (41%)
		Cadherin_repeat	1992..2089	CDD:206637	42/96 (44%)
		Cadherin_repeat	2116..2192	CDD:206637	22/78 (28%)
		Cadherin_repeat	2207..2300	CDD:206637	32/145 (22%)
		Cadherin_repeat	2308..2406	CDD:206637	33/98 (34%)
		Cadherin_repeat	2415..2505	CDD:206637	35/94 (37%)
		Cadherin_repeat	2514..2611	CDD:206637	30/117 (26%)
		Cadherin_repeat	2619..2731	CDD:206637	35/117 (30%)
		Cadherin_repeat	2739..2835	CDD:206637	28/103 (27%)
		Cadherin_repeat	2845..2941	CDD:206637	34/95 (36%)
		Cadherin_repeat	2950..3056	CDD:206637	30/110 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	172	1.000	Domainoid score	I3725
eggNOG	1	0.900	-	-		E33208_3B9B2
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2771
Inparanoid	1	1.050	1711	1.000	Inparanoid score	I72
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49414
OrthoDB	1	1.010	-	-		D23733at33208
OrthoFinder	1	1.000	-	-		FOG0001195
OrthoInspector	1	1.000	-	-		otm44009
orthoMCL	1	0.900	-	-		OOG6_100175
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3992
SonicParanoid	1	1.000	-	-		X2813
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.770