| Sequence 1: | NP_523446.2 | Gene: | ds / 33245 | FlyBaseID: | FBgn0284247 | Length: | 3556 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001317871.1 | Gene: | cdh-4 / 175590 | WormBaseID: | WBGene00000396 | Length: | 4328 | Species: | Caenorhabditis elegans |
| Alignment Length: | 3215 | Identity: | 786/3215 - (24%) |
|---|---|---|---|
| Similarity: | 1295/3215 - (40%) | Gaps: | 632/3215 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 106 DSGPPYIIVAEAGVETDLAIDRATGEIRTKVKLDRETRASYSLV-----AIPLS----------- 154
Fly 155 -GRNI----RVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNI- 213
Fly 214 -VSGNVNDAFRLSSHRERDGVLYLDLQISGFL-DRETTPGYSLLIEALDGGTPPLRGFMTVNITI 276
Fly 277 QDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPR 341
Fly 342 TGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKI 406
Fly 407 SESAQPGEFVARISVHDPD----SKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIV 467
Fly 468 SNYTLSVVATDKGTPPLHASKSIFLRITDVNDN--PPEFEQDLYHANVMEVADPGTSVLQVLAHD 530
Fly 531 R-DEGLNSA--LTYSLAETPETHAQW--FQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGV-- 588
Fly 589 ---PPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVN---AMVN 647
Fly 648 YTIGEGFKHLTEFEVRSASGEICIAG--ELDFERRSSYEFPVLATDRG--GLSTTAMIKMQLTDV 708
Fly 709 NDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRS 773
Fly 774 TGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAV-VFLSIIDAMQR-------PPIFEKA 830
Fly 831 RYNYYVK-EDIPR-GTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHE 893
Fly 894 AKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDK 958
Fly 959 DSGSSGQV--TYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLT 1021
Fly 1022 ILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNS 1086
Fly 1087 ISSSDVSQHFGIFPNSGWIYLRAPLDRETRD-RYQLTVLATDNGTPAAHAKTRVIVRVLDAND-- 1148
Fly 1149 NDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEISTREP 1213
Fly 1214 LDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVR 1278
Fly 1279 -------VRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVA 1336
Fly 1337 ASDGGNPPRETV--RMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRN 1399
Fly 1400 SVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVV---------ARLLDREVQSEFRLEIRA 1455
Fly 1456 LDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEAT--PVGTIIHNFTATDADTGTNG 1518
Fly 1519 DLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQA-PLDFEAVQEYLLIVQALDQSSNVTERL 1582
Fly 1583 QTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEI 1647
Fly 1648 TGGNGEGRFRINSQTGIIELVKSLPP-ATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQG 1711
Fly 1712 SHNNPPRFLQAVYRATI-LENVPSGSFVLQVTAK-SLHGAENANLSYEI-----PAGVANDLFHV 1769
Fly 1770 DWQRGII---------------------TTRGQFDRESQASYVL--------PVYVRDANRQSTL 1805
Fly 1806 SSSAVR------KQRSSD-------------------SIGD---------------------TSN 1824
Fly 1825 G-QHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHTVV-ASDLDEGPNAD-----L 1882
Fly 1883 IYSITGGNLGNKFSIDSSSGELS-ARPLDREQ---------------------HSRYTLQIQASD 1925
Fly 1926 RGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYS 1990
Fly 1991 LANETQ---------WQFAIDGQSGLITTVGKLDRELQASYNFMVLATDG-GRYEVRSATVPVQI 2045
Fly 2046 NVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRIN 2110
Fly 2111 PSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVML 2175
Fly 2176 KENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSM 2240
Fly 2241 SALSRGRALHYEEEIDE--------SSEED---PNNSTRSQRALTSSSFALTNSQPNEIRVVLVA 2294
Fly 2295 RTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRY 2359
Fly 2360 HIVDGNHDNAFVIEPAF-----SGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTAT---IRV 2416
Fly 2417 QIVDVNDNQPTFPPN------NLVTVSEATELGAVITSISANDVDTY--PALTYRLGAESTVDIE 2473
Fly 2474 NMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTVLTVRVNDEND--------NAP 2530
Fly 2531 VFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNG 2595
Fly 2596 VVSVNMSRLQPAVSSSGDY-------FVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQY 2653
Fly 2654 RAQISEAAPLGSVVLQLGQDALDQSLAIIAGNEESAFELLQSK----------------AIVLVK 2702
Fly 2703 PLDRERNDLYKLRLVLSHPHGPPLISSLNSSSG-----ISVIITILDANDNFPIFDRSAKYEAEI 2762
Fly 2763 SELAPLRYSIAQLQAIDADQENTPNSEVVY-----DITSGNDEHMFTIDLVTGVLFVNNRLDYDS 2822
Fly 2823 GAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHAS 2887
Fly 2888 DLDKGPFGQLNY--SIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGK- 2949
Fly 2950 --KASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSA 3012
Fly 3013 PHS---------HFKVNRSSGAVLIKRKLK 3033 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ds | NP_523446.2 | CA | 111..172 | CDD:214520 | 19/81 (23%) |
| Cadherin_repeat | 178..282 | CDD:206637 | 25/106 (24%) | ||
| Cadherin_repeat | 291..389 | CDD:206637 | 29/97 (30%) | ||
| Cadherin_repeat | 406..500 | CDD:206637 | 24/97 (25%) | ||
| Cadherin_repeat | 509..607 | CDD:206637 | 32/107 (30%) | ||
| Cadherin_repeat | 616..711 | CDD:206637 | 33/101 (33%) | ||
| Cadherin_repeat | 719..820 | CDD:206637 | 22/101 (22%) | ||
| Cadherin_repeat | 832..927 | CDD:206637 | 27/96 (28%) | ||
| Cadherin_repeat | 937..1032 | CDD:206637 | 22/96 (23%) | ||
| Cadherin_repeat | 1040..1149 | CDD:206637 | 28/111 (25%) | ||
| Cadherin_repeat | 1158..1252 | CDD:206637 | 19/93 (20%) | ||
| Cadherin_repeat | 1263..1361 | CDD:206637 | 35/106 (33%) | ||
| Cadherin_repeat | 1369..1481 | CDD:206637 | 22/120 (18%) | ||
| Cadherin_repeat | 1489..1598 | CDD:206637 | 26/111 (23%) | ||
| Cadherin_repeat | 1614..1710 | CDD:206637 | 27/96 (28%) | ||
| Cadherin_repeat | 1723..1843 | CDD:206637 | 38/202 (19%) | ||
| Cadherin_repeat | 1853..1948 | CDD:206637 | 23/122 (19%) | ||
| Cadherin_repeat | 1957..2053 | CDD:206637 | 28/105 (27%) | ||
| Cadherin_repeat | 2061..2154 | CDD:206637 | 26/92 (28%) | ||
| CA_like | 2171..>2232 | CDD:481204 | 3/60 (5%) | ||
| Cadherin_repeat | 2326..2424 | CDD:206637 | 35/105 (33%) | ||
| Cadherin_repeat | 2434..2528 | CDD:206637 | 22/103 (21%) | ||
| Cadherin_repeat | 2549..2641 | CDD:206637 | 20/98 (20%) | ||
| Cadherin_repeat | 2652..2748 | CDD:206637 | 22/116 (19%) | ||
| Cadherin_repeat | 2758..2858 | CDD:206637 | 26/104 (25%) | ||
| Cadherin_repeat | 2866..2960 | CDD:206637 | 24/98 (24%) | ||
| Cadherin_repeat | 2985..3071 | CDD:206637 | 13/58 (22%) | ||
| cdh-4 | NP_001317871.1 | Cadherin_repeat | 160..254 | CDD:206637 | |
| CA | 416..490 | CDD:214520 | |||
| Cadherin_repeat | 506..570 | CDD:206637 | 14/50 (28%) | ||
| Cadherin_repeat | 615..716 | CDD:206637 | 25/103 (24%) | ||
| Cadherin_repeat | 724..822 | CDD:206637 | 29/98 (30%) | ||
| Cadherin_repeat | 832..925 | CDD:206637 | 23/97 (24%) | ||
| Cadherin_repeat | 940..1042 | CDD:206637 | 32/106 (30%) | ||
| Cadherin_repeat | 1051..1152 | CDD:206637 | 33/101 (33%) | ||
| Cadherin_repeat | 1175..1235 | CDD:206637 | 17/66 (26%) | ||
| Cadherin_repeat | 1269..1353 | CDD:206637 | 26/88 (30%) | ||
| Cadherin_repeat | 1367..1463 | CDD:206637 | 22/98 (22%) | ||
| Cadherin_repeat | 1473..1562 | CDD:206637 | 27/102 (26%) | ||
| Cadherin_repeat | 1674..1779 | CDD:206637 | 34/107 (32%) | ||
| Cadherin_repeat | 1887..1979 | CDD:206637 | 25/110 (23%) | ||
| Cadherin_repeat | 1988..2075 | CDD:206637 | 27/97 (28%) | ||
| Cadherin_repeat | 2085..2176 | CDD:206637 | 20/97 (21%) | ||
| Cadherin_repeat | 2191..2280 | CDD:206637 | 15/88 (17%) | ||
| Cadherin_repeat | 2291..2386 | CDD:206637 | 19/95 (20%) | ||
| CA | <2449..2503 | CDD:214520 | 16/57 (28%) | ||
| Cadherin_repeat | 2510..2598 | CDD:206637 | 26/91 (29%) | ||
| Cadherin_repeat | 2612..2708 | CDD:206637 | 23/158 (15%) | ||
| Cadherin_repeat | 2718..2808 | CDD:206637 | 34/102 (33%) | ||
| Cadherin_repeat | 2817..2903 | CDD:206637 | 22/98 (22%) | ||
| CA_like | 2941..3009 | CDD:481204 | 22/97 (23%) | ||
| Cadherin_repeat | 3018..3109 | CDD:206637 | 22/113 (19%) | ||
| Cadherin_repeat | 3117..3212 | CDD:206637 | 26/106 (25%) | ||
| Cadherin_repeat | 3221..3322 | CDD:206637 | 25/102 (25%) | ||
| Cadherin_repeat | 3332..3418 | CDD:206637 | 14/68 (21%) | ||
| Cadherin_repeat | 3440..3536 | CDD:206637 | |||
| EGF | 3710..3749 | CDD:238010 | |||
| LamG | 3781..3907 | CDD:214598 | |||
| EGF | 3933..3963 | CDD:394967 | |||
| EGF_CA | 3968..4004 | CDD:238011 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||