Protein Alignment ds and pcdha8l

DIOPT Version :10

• Sequence 1: NP_523446.2
• Gene: ds / 33245
• FlyBaseID: FBgn0284247
• Length: 3556
• Species: Drosophila melanogaster
• Sequence 2: XP_017214536.2
• Gene: pcdha8l / 108179154
• ZFINID: ZDB-GENE-141215-68
• Length: 791
• Species: Danio rerio
• Alignment Length: 846
• Identity: 234/846 - (27%)
• Similarity: 377/846 - (44%)
• Gaps: 137/846 - (16%)

  Fly   830 ARYNYYVKEDIPRGTVVGSVIAASG-DVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHE 893
            |:..|.:.|::..||:||::....| ||:.....|:.|.||..|..|.:..|:|.:.:.|.:|.|
Zfish    31 AQIRYSIPEEVKEGTIVGNIAKDLGLDVSTLLDRRFRIVSGSNDALFQVNQNNGMLYVGKLIDRE 95

  Fly   894 A----KSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAH 954
            |    .:..|:::: |:.|.|:..| .|.:|:.||||:||.|....|.:.:.||...|.......
Zfish    96 ALCDGNAACLISLK-TVVENPLEIH-YVEVEITDVNDHAPSFANKDVLLEIAESTIPGEDFQLQE 158

  Fly   955 AHDKDSGSSGQVTYSLVKESGKGLFAIDARSGH-------LILSQHLDYESSQRHTLIVTATDGG 1012
            |:|.|||.:....|.|   |....|.|:.|...       |.|.:.||.|....|:|.|||.|||
Zfish   159 AYDPDSGVNSVRFYKL---SQTEYFEIELRENGGEKKVPVLKLRKSLDRERQVIHSLTVTAVDGG 220

  Fly  1013 VPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVD 1077
            .|..|.:..|.|.|.|.|||.|.|.::.|||::.|:..:...:|::||:|||.|.|..|.|..
Zfish   221 NPPRSGSTVINVTVLDDNDNRPKFSQELYSVSLRENAPLGTLVIKLNATDLDEGQNGEIVYSF-- 283

  Fly  1078 AGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVR 1142
              |.|:...|..:     |.: .|:|.|.::..||.|..:.|::.|:|:|.|.|...:..|:|::
Zfish   284 --VKNIEKYIYDT-----FDL-DNTGEIRVKGSLDFEKSNVYRIAVMASDKGQPPKTSNCRIIIK 340

  Fly  1143 VLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAA--------IRYSLLPINSSF 1199
            |:|.|||.|:.:.:.....:.|:.:.|:|:.:|:.:|.|.|.|..        :.:.|.|   ||
Zfish   341 VIDENDNAPEIEVTSLSDVVPEDSKPGAVISLVSITDKDSGVNGKVVCRISDDVPFELKP---SF 402

  Fly  1200 QVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPE-IADPQEDV 1263
            :.:..:  :.|...|||||...||:.:.|.|.|.|..|:...:::.:||||||||| :.:|.|
Zfish   403 KDNMYS--LVTNAKLDRELTSHYDVTITATDLGQPPLSSIKTLKVQISDVNDNAPEFVHNPLE-- 463

  Fly  1264 VSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGH--GLFSIDPTSGVIRTRVVLDHE 1326
            :.:.|...||..:..|.|.|||..:||:|||.|::...:..|  ...:::..:|.|......|.|
Zfish   464 LYLMENNAPGASIYSVSAFDRDLNENAAITYQIIREEGTRSHMSSFLNVNADNGHIHALKSFDFE 528

  Fly  1327 ERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFT-------SSSLVFRVREDAALGHVV 1384
            ....::..:.|:|.|:|...:...:.|.:||.|||.|...       |:..|..:..:...||:|
Zfish   529 SVKTFQFHIIATDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLV 593

  Fly  1385 GSISPIERPADVVRN-----SVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDRE 1444
            ..:...:  ||:..|     |::|..|                .:.|.:||::|.:...|.....
Zfish   594 TKVRAYD--ADIGYNGWLLFSLQEVSE----------------HSLFALDRYTGQIRTLRSFTET 640

  Fly  1445 VQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTA 1509
            .:::.:|.|...|.  .|...|:..||.::|.:        |::.                 |.|
Zfish   641 DEAQHKLVILVKDN--GNVSLSATATVIVKVVE--------PKEA-----------------FAA 678

  Fly  1510 TDA-----DTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIV 1569
            :|.     |...|....|.:|..         .::|:..:.|:...:.:|.....:...:||
Zfish   679 SDVKNAEKDEEENNVTFYLIITL---------GSVSVLFVISIIVLIVMQCSKSTDYSSKYL--- 731

  Fly  1570 QALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTA-------SLFISDATR--IGE 1625
                |.:|....|..|:..|     :.|.....|.|..|.|.|.       :|.|.|..|  .||
Zfish   732 ----QDTNYDGTLCHSIQYR-----SGDKRYMLVGPRMSIGSTIAPGSNRNTLVIPDRRRRDSGE 787

  Fly  1626 V 1626
            |
Zfish   788 V 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ds	NP_523446.2	CA	111..172	CDD:214520
		Cadherin_repeat	178..282	CDD:206637
		Cadherin_repeat	291..389	CDD:206637
		Cadherin_repeat	406..500	CDD:206637
		Cadherin_repeat	509..607	CDD:206637
		Cadherin_repeat	616..711	CDD:206637
		Cadherin_repeat	719..820	CDD:206637
		Cadherin_repeat	832..927	CDD:206637	31/99 (31%)
		Cadherin_repeat	937..1032	CDD:206637	34/101 (34%)
		Cadherin_repeat	1040..1149	CDD:206637	35/108 (32%)
		Cadherin_repeat	1158..1252	CDD:206637	29/101 (29%)
		Cadherin_repeat	1263..1361	CDD:206637	27/99 (27%)
		Cadherin_repeat	1369..1481	CDD:206637	23/116 (20%)
		Cadherin_repeat	1489..1598	CDD:206637	17/113 (15%)
		Cadherin_repeat	1614..1710	CDD:206637	7/15 (47%)
		Cadherin_repeat	1723..1843	CDD:206637
		Cadherin_repeat	1853..1948	CDD:206637
		Cadherin_repeat	1957..2053	CDD:206637
		Cadherin_repeat	2061..2154	CDD:206637
		CA_like	2171..>2232	CDD:481204
		Cadherin_repeat	2326..2424	CDD:206637
		Cadherin_repeat	2434..2528	CDD:206637
		Cadherin_repeat	2549..2641	CDD:206637
		Cadherin_repeat	2652..2748	CDD:206637
		Cadherin_repeat	2758..2858	CDD:206637
		Cadherin_repeat	2866..2960	CDD:206637
		Cadherin_repeat	2985..3071	CDD:206637
pcdha8l	XP_017214536.2	None