| Sequence 1: | NP_523446.2 | Gene: | ds / 33245 | FlyBaseID: | FBgn0284247 | Length: | 3556 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_031762583.1 | Gene: | cdh23 / 100493009 | XenbaseID: | XB-GENE-957613 | Length: | 3353 | Species: | Xenopus tropicalis |
| Alignment Length: | 3079 | Identity: | 902/3079 - (29%) |
|---|---|---|---|
| Similarity: | 1391/3079 - (45%) | Gaps: | 416/3079 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 185 ENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVND-AFRLSSHRERDGVLYLDLQISGFLDRET 248
Fly 249 TPGYSLLIEALDG-GTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASD 312
Fly 313 TDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGE-QPLETT 376
Fly 377 AFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGD 441
Fly 442 GH--FALTTRDNSIYLVIVHLPLDREIVSN--YTLSVVATDKGTPPLH--------ASKSIFLRI 494
Fly 495 TDVNDNPPEFEQDLYHANVMEVADPGTSV-LQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDP 558
Fly 559 QT--GLITTRSHI----DCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYN 617
Fly 618 VSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSS 682
Fly 683 YEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDP 747
Fly 748 DYGNFGQVSYRIVAGNEAGIFR------IDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLR 806
Fly 807 SNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDP 871
Fly 872 DGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQAT---LGEPPVYGHTQVNIEVEDVNDNAPEFEA 933
Fly 934 SMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYS---------LVKESGKGLFAIDARSGHLI 989
Fly 990 LSQH--LDYESSQRHTLIVTATDGGVPSL--STNLTILVDVQDVNDNPPVFEKDEYSVNVSESRS 1050
Fly 1051 INAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRET 1115
Fly 1116 RDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDL 1180
Fly 1181 DLGENAAIRYSLLPIN--SSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPV---RSARV 1240
Fly 1241 PVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGH 1305
Fly 1306 GLFSIDPTSGVIRTRV-VLDHEERSIYRLGVAA--SDGGNPPRETVRMLRVEVLDLNDNRPTFTS 1367
Fly 1368 SSLV-FRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAA---FDI 1428
Fly 1429 DRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQ 1493
Fly 1494 VSEATPVGTIIHNFTATDADTGTN-GDLQYRLIRYFPQLN-----ESQEQAMSLFRMDSLTGALS 1552
Fly 1553 LQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFI 1617
Fly 1618 SDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRI---NSQTGIIELVKSLPPATEDVE 1679
Fly 1680 KGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAV-YRATILENVPSGSFVLQVTA 1743
Fly 1744 KSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTR-GQFDRESQASYVLPVYVRDANRQSTLSS 1807
Fly 1808 SAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPEN--SEPGVIHTVV 1870
Fly 1871 ASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELS-ARPLDREQ-HSRYTLQIQASDRGQPKSRQ 1933
Fly 1934 --GHCNITIFVEDQNDNAPRFKLSKYTG--SVQEDAPLGTSVVQISAVDADLGVNARLVYSL-AN 1993
Fly 1994 ETQWQFAIDGQSG--LITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPI 2056
Fly 2057 FERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQS 2121
Fly 2122 LASESGKLLHLEVVARDKGNPPQS-----SLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPS 2181
Fly 2182 GTRLL----QVVALRSD-GRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMS 2241
Fly 2242 ALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYA 2306
Fly 2307 ELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFV 2371
Fly 2372 IEPAFSGIVR-TNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTF-PPNNLV 2434
Fly 2435 TVSEATELGAVITSISANDVDTYPALTYR----LGAESTVDI--ENMSIFALDRYSGKLVLKRRL 2493
Fly 2494 DYELQQEYELDVIASDAAHEA--RTV------LTVRVNDENDNAPVFLAQQPPAYFAILPAISEI 2550
Fly 2551 SESLSVDFDLLTVNATDADSEGNNSKVIYIIE---PAQEGFSVHPSN--GVV----SVNMSRLQP 2606
Fly 2607 AVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQL- 2670
Fly 2671 ------GQDALDQSLAIIAGNEESAFELLQSKA-IVLVKPLDRERNDLYKLRLVLSHPHGPPLIS 2728
Fly 2729 SLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYD 2793
Fly 2794 ITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYE---LIIRACDSHHQRPLCSLQPFRLELHDE 2855
Fly 2856 NDNEPKF--PLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDS 2918
Fly 2919 ESGLVTSAFVFDYEQRQRYDMELLASDMGGK---KASVAVRVEIESRDEFTPQFTERTYRFVLPA 2980
Fly 2981 AVAL-----------PQGYVVGQVT-ATDSDSGPDGRVVYQLSAPHSHFKVNRSSGAVLI---KR 3030
Fly 3031 KLKLDGDGDGNLYMDGRDISLVISASSGRH----NSL---------SSMAVVEIALDPLAHPGTN 3082
Fly 3083 LA----SAGGSSSGSIGDWAIGLL 3102 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ds | NP_523446.2 | CA | 111..172 | CDD:214520 | |
| Cadherin_repeat | 178..282 | CDD:206637 | 31/98 (32%) | ||
| Cadherin_repeat | 291..389 | CDD:206637 | 33/98 (34%) | ||
| Cadherin_repeat | 406..500 | CDD:206637 | 28/105 (27%) | ||
| Cadherin_repeat | 509..607 | CDD:206637 | 27/104 (26%) | ||
| Cadherin_repeat | 616..711 | CDD:206637 | 33/94 (35%) | ||
| Cadherin_repeat | 719..820 | CDD:206637 | 26/106 (25%) | ||
| Cadherin_repeat | 832..927 | CDD:206637 | 33/97 (34%) | ||
| Cadherin_repeat | 937..1032 | CDD:206637 | 23/107 (21%) | ||
| Cadherin_repeat | 1040..1149 | CDD:206637 | 36/108 (33%) | ||
| Cadherin_repeat | 1158..1252 | CDD:206637 | 32/98 (33%) | ||
| Cadherin_repeat | 1263..1361 | CDD:206637 | 36/100 (36%) | ||
| Cadherin_repeat | 1369..1481 | CDD:206637 | 26/115 (23%) | ||
| Cadherin_repeat | 1489..1598 | CDD:206637 | 34/114 (30%) | ||
| Cadherin_repeat | 1614..1710 | CDD:206637 | 30/98 (31%) | ||
| Cadherin_repeat | 1723..1843 | CDD:206637 | 36/121 (30%) | ||
| Cadherin_repeat | 1853..1948 | CDD:206637 | 36/100 (36%) | ||
| Cadherin_repeat | 1957..2053 | CDD:206637 | 35/100 (35%) | ||
| Cadherin_repeat | 2061..2154 | CDD:206637 | 21/97 (22%) | ||
| CA_like | 2171..>2232 | CDD:481204 | 17/65 (26%) | ||
| Cadherin_repeat | 2326..2424 | CDD:206637 | 38/98 (39%) | ||
| Cadherin_repeat | 2434..2528 | CDD:206637 | 31/107 (29%) | ||
| Cadherin_repeat | 2549..2641 | CDD:206637 | 24/100 (24%) | ||
| Cadherin_repeat | 2652..2748 | CDD:206637 | 31/103 (30%) | ||
| Cadherin_repeat | 2758..2858 | CDD:206637 | 26/102 (25%) | ||
| Cadherin_repeat | 2866..2960 | CDD:206637 | 25/96 (26%) | ||
| Cadherin_repeat | 2985..3071 | CDD:206637 | 27/102 (26%) | ||
| cdh23 | XP_031762583.1 | Cadherin_repeat | 43..129 | CDD:206637 | 31/98 (32%) |
| Cadherin_repeat | 137..232 | CDD:206637 | 33/98 (34%) | ||
| Cadherin_repeat | 241..345 | CDD:206637 | 29/110 (26%) | ||
| Cadherin_repeat | 353..455 | CDD:206637 | 27/105 (26%) | ||
| Cadherin_repeat | 464..556 | CDD:206637 | 33/94 (35%) | ||
| Cadherin_repeat | 564..666 | CDD:206637 | 27/109 (25%) | ||
| Cadherin_repeat | 674..773 | CDD:206637 | 33/98 (34%) | ||
| Cadherin_repeat | 781..885 | CDD:206637 | 23/109 (21%) | ||
| Cadherin_repeat | 893..989 | CDD:206637 | 35/107 (33%) | ||
| Cadherin_repeat | 998..1097 | CDD:206637 | 32/99 (32%) | ||
| Cadherin_repeat | 1105..1202 | CDD:206637 | 35/102 (34%) | ||
| Cadherin_repeat | 1217..1307 | CDD:206637 | 28/116 (24%) | ||
| Cadherin_repeat | 1316..1412 | CDD:206637 | 33/105 (31%) | ||
| Cadherin_repeat | 1423..1521 | CDD:206637 | 31/103 (30%) | ||
| Cadherin_repeat | 1531..1628 | CDD:206637 | 36/119 (30%) | ||
| Cadherin_repeat | 1636..1738 | CDD:206637 | 36/101 (36%) | ||
| Cadherin_repeat | 1750..1845 | CDD:206637 | 33/96 (34%) | ||
| Cadherin_repeat | 1853..1953 | CDD:206637 | 22/103 (21%) | ||
| Cadherin_repeat | 1961..2063 | CDD:206637 | 31/152 (20%) | ||
| Cadherin_repeat | 2071..2167 | CDD:206637 | 37/97 (38%) | ||
| Cadherin_repeat | 2178..2287 | CDD:206637 | 31/108 (29%) | ||
| Cadherin_repeat | 2299..2396 | CDD:206637 | 25/106 (24%) | ||
| Cadherin_repeat | 2404..2502 | CDD:206637 | 30/102 (29%) | ||
| Cadherin_repeat | 2511..2605 | CDD:206637 | 26/103 (25%) | ||
| Cadherin_repeat | 2618..2717 | CDD:206637 | 26/98 (27%) | ||
| Cadherin_repeat | 2733..2840 | CDD:206637 | 28/117 (24%) | ||
| Cadherin_repeat | 2849..2950 | CDD:206637 | 5/20 (25%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||