DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ds and pcdha8

DIOPT Version :9

Sequence 1:NP_001285551.1 Gene:ds / 33245 FlyBaseID:FBgn0284247 Length:3556 Species:Drosophila melanogaster
Sequence 2:XP_002935957.3 Gene:pcdha8 / 100490196 XenbaseID:XB-GENE-6037559 Length:802 Species:Xenopus tropicalis


Alignment Length:692 Identity:203/692 - (29%)
Similarity:331/692 - (47%) Gaps:67/692 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   833 NYYVKEDIPRGTVVGSVIAASG-DVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHE--- 893
            :|.:.|:...||.||.:....| :::..:.....|.|.|...||.:...:|.:.:...:|.|   
 Frog    34 HYIIPEESKHGTFVGRIAQDLGLEISEINSRVLRIVSRDEKEYFQVNLQNGILFVNNIIDREEIC 98

  Fly   894 -AKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHD 957
             ..:..:::::..:.:|....|  |::|:||:|||.|.|.|....|.:.||..:.:......|.|
 Frog    99 PETTVCIIHLEIIVDKPVHIYH--VDVEIEDINDNYPVFSAKEYSIVIAESRVVESKFPLEGAVD 161

  Fly   958 KDSGSSGQVTYSLVKESGKGLFAID-------ARSGHLILSQHLDYESSQRHTLIVTATDGGVPS 1015
            :|.|::....|.|   |..|:|||:       :.|..|:|.:.||.|:...:.|.:||.|||.|.
 Frog   162 EDVGTNSIRAYEL---SSNGVFAIEIKKDKHQSESVELVLKKPLDRENQPFYNLTLTAFDGGKPK 223

  Fly  1016 LSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGV 1080
            ||....:|:.|||.|||.|.|::..|.|.:.|:......:.:|.|:|.|.|:|.::||..     
 Frog   224 LSGTTQLLITVQDSNDNAPAFQESAYEVTLLENAMKGTLVAKVIATDPDEGDNGKVTYEF----- 283

  Fly  1081 DNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLD 1145
                :|...|.|...|.|...:|.|.:...:|.|..:.|.:.:.|||.|........:::|.|:|
 Frog   284 ----SSQVPSQVRSTFTIDQETGEIRVIGEVDFEKNNYYNIRIDATDKGQNPMTGHCKILVSVID 344

  Fly  1146 ANDNDPKFQKSKYEFRIEENLRRGSVVGVVTA--SDLDLGENAAIRYSL---LPINSSFQVHPVT 1205
            .|||.|:...:.....:.|:...|:.|.::..  .|.|.|.|..:...:   :|    |:::|..
 Frog   345 INDNPPEMTVTSLSVPVPEDSPMGTTVAIIRIQDKDKDSGANGKVTCFIAGKVP----FKLNPTL 405

  Fly  1206 GE---ISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVR 1267
            .|   ::...|||||:..:|::.:.|||.|:||.|....:.:.:||||||||..|. ..|.:.:.
 Frog   406 REYYALTVDGPLDREIASVYEVEIIARDGGSPVLSVAQTINVEISDVNDNAPSFAQ-LSDTIFIT 469

  Fly  1268 EEQPPGTEVVRVRAVDRDHGQNASITYSIVKG--RDSDGHGLFSIDPTSGVIRTRVVLDHEERSI 1330
            |..|||:.|..|.|.|.|..||:.||||:.:|  .........||:|.||.|...:..|.|:...
 Frog   470 ENNPPGSHVHTVSATDSDINQNSFITYSLTEGFIEGIPVSSYLSINPESGKIFALLSFDQEQIHF 534

  Fly  1331 YRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTF--TSSSLVFRVRE----DAALGHVVGSISP 1389
            ::..|.|.|.|..|.....:|.|.::|:|||.||.  ..|:|.|.|.|    .|.:||.|..|..
 Frog   535 FQCSVKACDAGLAPLSGNLILNVFIVDVNDNAPTLFPPFSNLDFPVTEIVSRSAKIGHPVTKIRA 599

  Fly  1390 IERPADVVRNSVEESFEDLRVTYTL-NPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEI 1453
            ::  ||...|:.        ::|.| :|:.|    ..|.:.:|:|.:|::|.:....:.|::|.|
 Frog   600 VD--ADSGYNAF--------LSYGLKDPMEK----TPFGVGQHTGEIVISRPVLESDRDEYKLFI 650

  Fly  1454 RALDTTASNNP-QSSAITVKIEVAD-VNDNAPEWPQDPIDLQ 1493
            ...|   ..:| .||.:|:.|.:.: :.|...|..|..|:.:
 Frog   651 VVKD---HGDPVLSSTVTITIVLVEKIQDITVEQNQKGIEYE 689

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dsNP_001285551.1 CA 111..172 CDD:214520
Cadherin_repeat 178..282 CDD:206637
Cadherin_repeat 291..389 CDD:206637
Cadherin_repeat 406..500 CDD:206637
Cadherin_repeat 509..607 CDD:206637
Cadherin_repeat 616..711 CDD:206637
Cadherin_repeat 719..820 CDD:206637
Cadherin_repeat 832..927 CDD:206637 22/98 (22%)
Cadherin_repeat 937..1032 CDD:206637 34/101 (34%)
Cadherin_repeat 1040..1149 CDD:206637 29/108 (27%)
Cadherin_repeat 1158..1252 CDD:206637 28/101 (28%)
Cadherin_repeat 1263..1361 CDD:206637 33/99 (33%)
Cadherin_repeat 1369..1481 CDD:206637 30/118 (25%)
Cadherin_repeat 1489..1598 CDD:206637 1/5 (20%)
Cadherin_repeat 1614..1710 CDD:206637
Cadherin_repeat 1723..1843 CDD:206637
Cadherin_repeat 1853..1948 CDD:206637
Cadherin_repeat 1957..2053 CDD:206637
Cadherin_repeat 2061..2154 CDD:206637
Cadherin_repeat 2170..2318 CDD:206637
Cadherin_repeat 2326..2424 CDD:206637
Cadherin_repeat 2434..2528 CDD:206637
Cadherin_repeat 2549..2641 CDD:206637
Cadherin_repeat 2652..2748 CDD:206637
Cadherin_repeat 2758..2858 CDD:206637
Cadherin_repeat 2866..2960 CDD:206637
Cadherin_repeat 2985..3071 CDD:206637
pcdha8XP_002935957.3 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 56 1.000 Domainoid score I10813
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.