Protein Alignment CG2839 and MRC2

DIOPT Version :10

• Sequence 1: NP_608540.1
• Gene: CG2839 / 33244
• FlyBaseID: FBgn0031273
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_006030.2
• Gene: MRC2 / 9902
• HGNCID: 16875
• Length: 1479
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 67/298 - (22%)
• Similarity: 113/298 - (37%)
• Gaps: 57/298 - (19%)

  Fly    18 CNVFAENDILQDPLIS-------SYDRLKKLGEMCLIDILPILENISEQQ-----KEGYTANFRI 70
            |..|.:.|.|.|....       |:.......|....|:|.|.| |.||.     ..||::...|
Human   235 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITE-IHEQTYINGLLTGYSSTLWI 298

  Fly    71 -FNETQGILDRIEGHQEVNDKQLK------------------ALKVKMEGHFMDLHAKMEIKVKK 116
             .|:    ||...|.|..::..||                  .::.:..|.:.:...       .
Human   299 GLND----LDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDC-------S 352

  Fly   117 LSLEKSLRKALNA-LQCSLDTRNVSSKVSLHPEFEKVGSRFFYIERHVKQNWFDAMTKCREMGGH 180
            ::|....:|..|| .:.:...|..:.||...|.::......:.::.. |::|.::...|...||.
Human   353 IALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAE-KRSWQESKKACLRGGGD 416

  Fly   181 LASPQNEEELHLISQ--KLDTESYWLDLSDLTDHGQYISLVSGSKAPFLKWNKGQPN--RENAQ- 240
            |.|..:..||..|::  |.:.|..|:.|:||.....: ....||...|..|:..:||  |::.:
Human   417 LVSIHSMAELEFITKQIKQEVEELWIGLNDLKLQMNF-EWSDGSLVSFTHWHPFEPNNFRDSLED 480

  Fly   241 CVRVKG--GLYQTFQCDHRVLFIC----QANQNRKKED 272
            ||.:.|  |.:....|:..:..||    |.:|...:||
Human   481 CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEED 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2839	NP_608540.1	CLECT	147..263	CDD:214480	31/126 (25%)
MRC2	NP_006030.2	beta-trefoil_Ricin_MRC2	42..165	CDD:467786
		FN2	180..228	CDD:128373
		CLECT	247..361	CDD:153057	21/125 (17%)
		CLECT	382..505	CDD:214480	30/124 (24%)
		CLECT	521..644	CDD:214480
		CLECT	669..809	CDD:214480
		CLECT	829..951	CDD:214480
		CLECT	972..1108	CDD:214480
		CLECT	1137..1245	CDD:153057
		CLECT	1261..1394	CDD:214480
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1450..1479