DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2839 and Mrc2

DIOPT Version :9

Sequence 1:	NP_608540.1	Gene:	CG2839 / 33244	FlyBaseID:	FBgn0031273	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	XP_006532469.1	Gene:	Mrc2 / 17534	MGIID:	107818	Length:	1513	Species:	Mus musculus

Alignment Length:	298	Identity:	66/298 - (22%)
Similarity:	113/298 - (37%)	Gaps:	57/298 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 CNVFAENDILQDPLIS-------SYDRLKKLGEMCLIDILPILENISEQQ-----KEGYTANFRI 70
            |..|.:.|.|.|....       |:.......|....|:|.|.| |.||.     ..||::...|
Mouse   269 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITE-IHEQTYINGLLTGYSSTLWI 332

  Fly    71 -FNETQGILDRIEGHQEVNDKQLK------------------ALKVKMEGHFMDLHAKMEIKVKK 116
             .|:    ||...|.|..::..||                  .::.:..|.:.:...       .
Mouse   333 GLND----LDTSGGWQWSDNSPLKYLNWESDQPDNPGEENCGVIRTESSGGWQNHDC-------S 386

  Fly   117 LSLEKSLRKALNA-LQCSLDTRNVSSKVSLHPEFEKVGSRFFYIERHVKQNWFDAMTKCREMGGH 180
            ::|....:|..|| ::.....|..:.||...|.::......:.::.. |::|.::...|...||.
Mouse   387 IALPYVCKKKPNATVEPIQPDRWTNVKVECDPSWQPFQGHCYRLQAE-KRSWQESKRACLRGGGD 450

  Fly   181 LASPQNEEELHLISQ--KLDTESYWLDLSDLTDHGQYISLVSGSKAPFLKWNKGQPN--RENAQ- 240
            |.|..:..||..|::  |.:.|..|:.|:||.....: ....||...|..|:..:||  |::.:
Mouse   451 LLSIHSMAELEFITKQIKQEVEELWIGLNDLKLQMNF-EWSDGSLVSFTHWHPFEPNNFRDSLED 514

  Fly   241 CVRVKG--GLYQTFQCDHRVLFIC----QANQNRKKED 272
            ||.:.|  |.:....|:..:..||    :.:|...:||
Mouse   515 CVTIWGPEGRWNDSPCNQSLPSICKKAGRLSQGAAEED 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2839	NP_608540.1	CLECT	147..263	CDD:214480	31/126 (25%)
Mrc2	XP_006532469.1	CLECT	1165..1277	CDD:214480
		CLECT	1294..1427	CDD:214480
		RICIN	80..195	CDD:214672
		FN2	214..262	CDD:128373
		CLECT	281..395	CDD:153057	21/125 (17%)
		CLECT	416..539	CDD:214480	30/124 (24%)
		CLECT	555..678	CDD:214480
		CLECT	703..843	CDD:214480
		CLECT	863..985	CDD:214480
		CLECT	1006..1142	CDD:214480
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910