DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-21Cb and SFTPA2

DIOPT Version :9

Sequence 1:	NP_608539.2	Gene:	lectin-21Cb / 33242	FlyBaseID:	FBgn0040106	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	XP_005270185.1	Gene:	SFTPA2 / 729238	HGNCID:	10799	Length:	265	Species:	Homo sapiens

Alignment Length:	171	Identity:	39/171 - (22%)
Similarity:	62/171 - (36%)	Gaps:	49/171 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 YLDAALQKAINSLQCSLKNTK--------VMSTGKPHPEFQKLGSRYFYIERHVRQNWFDA-ADK 156
            :||..||..::..:..:..|:        :|:.|:  ..|...|          :...||| .:.
Human   119 HLDEELQATLHDFRHQILQTRGALSLQGSIMTVGE--KVFSSNG----------QSITFDAIQEA 171

  Fly   157 CRRMGGHLATPQDEDELYLIRKQLEARWFWLDISNLVDKDQ---YISL-----------ATGKEV 207
            |.|.||.:|.|::.:|       .||      |::.|.|..   |:.|           :.|..|
Human   172 CARAGGRIAVPRNPEE-------NEA------IASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPV 223

  Fly   208 SYLKWRHGEPKKSSTANCAYLYA-GDYYTYQCSDRNFFICQ 247
            :|..|..|||.......|..:|. |.:....|......||:
Human   224 NYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICE 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-21Cb	NP_608539.2	CLECT	137..247	CDD:153057	29/125 (23%)
SFTPA2	XP_005270185.1	Collagen	45..117	CDD:189968
SFTPA2	XP_005270185.1	CLECT_collectin_like	153..265	CDD:153061	32/137 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000