Protein Alignment lectin-21Cb and CD209

DIOPT Version :10

• Sequence 1: NP_608539.2
• Gene: lectin-21Cb / 33242
• FlyBaseID: FBgn0040106
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_066978.1
• Gene: CD209 / 30835
• HGNCID: 1641
• Length: 404
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 54/255 - (21%)
• Similarity: 93/255 - (36%)
• Gaps: 75/255 - (29%)

  Fly    21 QENNCPKVSLSERLEKRGEFSLVEFDPLLKFIV-----KNPHKELLGEIEGLVGHTENKLQPMKS 80
            ||....|.::.|..||..:..:.:....||..|     |:..:|:..|:        .:|:....
Human   171 QELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQEL--------TRLKAAVG 227

  Fly    81 VIPNQSKALLNYLDLHSKLEYLDAALQKAINSLQCSLKNTKVMSTGKPHP------EFQKLGSRY 139
            .:|.:||    ..:::.:|..|.||:::.     |             ||      .||  |:.|
Human   228 ELPEKSK----QQEIYQELTQLKAAVERL-----C-------------HPCPWEWTFFQ--GNCY 268

  Fly   140 FYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQ----------------LEARWFWLD 188
            |.  .:.::||.|:...|:.:|..|...:..:|...::.|                .|..|.|:|
Human   269 FM--SNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVD 331

  Fly   189 ISNLVDK-DQYISLATGKEVSYLKWRHGEPKKSSTANCAYLYAGDYYTYQCSDRNFFICQ 247
            .|.|:.. .||             |..|||......:||......:...:|:...|:||:
Human   332 GSPLLPSFKQY-------------WNRGEPNNVGEEDCAEFSGNGWNDDKCNLAKFWICK 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lectin-21Cb	NP_608539.2	CLECT	137..247	CDD:153057	27/126 (21%)
CD209	NP_066978.1	Endocytosis signal	14..15
		Endocytosis signal. /evidence=ECO:0000255	16..18
		Endocytosis signal. /evidence=ECO:0000255	31..34
		transmembrane domain	36..59
		GumC	<53..>225	CDD:442439	13/61 (21%)
		neck domain	60..249		19/89 (21%)
		CLECT_DC-SIGN_like	256..379	CDD:153060	31/140 (22%)