DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment lectin-21Cb and CLEC4E

DIOPT Version :9

Sequence 1:NP_608539.2 Gene:lectin-21Cb / 33242 FlyBaseID:FBgn0040106 Length:249 Species:Drosophila melanogaster
Sequence 2:NP_055173.1 Gene:CLEC4E / 26253 HGNCID:14555 Length:219 Species:Homo sapiens


Alignment Length:139 Identity:34/139 - (24%)
Similarity:52/139 - (37%) Gaps:38/139 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   132 FQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLA--TPQDEDELYLIRKQ-------------LE 181
            ||  .|.||:....:  :|..:...|..||.||.  ..|:|.|....:|.             :|
Human    87 FQ--SSCYFFSTDTI--SWALSLKNCSAMGAHLVVINSQEEQEFLSYKKPKMREFFIGLSDQVVE 147

  Fly   182 ARWFWLDISNLVDKDQYISLATGKEVSYLKWRHGEPKKSST-ANCAYLYAG-----DYYTYQCSD 240
            .:|.|:|.:.|.           |.:|:  |..|||...:| .:||.:...     ::....|..
Human   148 GQWQWVDGTPLT-----------KSLSF--WDVGEPNNIATLEDCATMRDSSNPRQNWNDVTCFL 199

  Fly   241 RNFFICQAV 249
            ..|.||:.|
Human   200 NYFRICEMV 208

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lectin-21CbNP_608539.2 CLECT 137..247 CDD:153057 30/130 (23%)
CLEC4ENP_055173.1 CLECT_DC-SIGN_like 80..207 CDD:153060 33/136 (24%)
Confers specificity for glucose/mannose-type carbohydrates. /evidence=ECO:0000303|PubMed:24101491 169..171 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR22802
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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