DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lectin-21Cb and FCER2

DIOPT Version :9

Sequence 1:	NP_608539.2	Gene:	lectin-21Cb / 33242	FlyBaseID:	FBgn0040106	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001207429.1	Gene:	FCER2 / 2208	HGNCID:	3612	Length:	321	Species:	Homo sapiens

Alignment Length:	239	Identity:	54/239 - (22%)
Similarity:	91/239 - (38%)	Gaps:	44/239 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QGAQENNCPKVSLSERLEKRGEFSLVEFDPLLKFIVKNPHKELLGEIEGLVGHTENKLQPMKSVI 82
            |.||::...::| .|..|.|.|          :..:|:...||...:.||    :..|...||..
Human    78 QMAQKSQSTQIS-QELEELRAE----------QQRLKSQDLELSWNLNGL----QADLSSFKSQE 127

  Fly    83 PNQSKALLNYLDLHSKLEYLDAALQKAINSLQCSLKNTKVMSTG---KPHPE----FQKLGSRYF 140
            .|:.....:.|:          .|::.:..|:..|:    :|:|   ...||    ||:   :.:
Human   128 LNERNEASDLLE----------RLREEVTKLRMELQ----VSSGFVCNTCPEKWINFQR---KCY 175

  Fly   141 YIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLEARWFWLDISNLVDKDQYISLATGK 205
            |..:..:| |..|...|..|.|.|.:....:|...:.|.......|:.:.||..|.::| ...|.
Human   176 YFGKGTKQ-WVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFI-WVDGS 238

  Fly   206 EVSYLKWRHGEP-KKSSTANCAYLYAGDYYTYQCSDRNF--FIC 246
            .|.|..|..||| .:|...:|..:.....:.....||..  ::|
Human   239 HVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVC 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-21Cb	NP_608539.2	CLECT	137..247	CDD:153057	27/113 (24%)
FCER2	NP_001207429.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..85		3/6 (50%)
		Repetitive region	69..89		3/10 (30%)
		RILP-like	<77..153	CDD:304877	20/99 (20%)
		Repetitive region	90..110		6/29 (21%)
		Repetitive region	111..131		6/23 (26%)
		CLECT	163..282	CDD:214480	30/123 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..321
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010