DRSC/TRiP Functional Genomics Resources

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Protein Alignment lectin-21Cb and CLEC4C

DIOPT Version :9

Sequence 1:NP_608539.2 Gene:lectin-21Cb / 33242 FlyBaseID:FBgn0040106 Length:249 Species:Drosophila melanogaster
Sequence 2:NP_001358319.1 Gene:CLEC4C / 170482 HGNCID:13258 Length:213 Species:Homo sapiens


Alignment Length:173 Identity:40/173 - (23%)
Similarity:62/173 - (35%) Gaps:49/173 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 MKSVIPNQ---SKALLNYLDLHSKL-EYLDAALQKAINSLQCSLKNTKVMSTG---KPHPEFQKL 135
            :.||:|:.   ||.:...    ||| ||     |:...||.|.::...:....   .|...||  
Human    38 VSSVVPHNFMYSKTVKRL----SKLREY-----QQYHPSLTCVMEGKDIEDWSCCPTPWTSFQ-- 91

  Fly   136 GSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLE---------------ARWF 185
             |..::|...: |:|..:...|..||..|......:|...|.:.|:               ..|.
Human    92 -SSCYFISTGM-QSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQ 154

  Fly   186 WLDISNLVDKDQYISLATGKEVSYLKWRHGEPKKSSTANCAYL 228
            |      ||:..|     .:.|::  |..||| .:....||.:
Human   155 W------VDQTPY-----NENVTF--WHSGEP-NNLDERCAII 183

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lectin-21CbNP_608539.2 CLECT 137..247 CDD:153057 23/107 (21%)
CLEC4CNP_001358319.1 CLECT_DC-SIGN_like 83..208 CDD:153060 26/119 (22%)
Carbohydrate binding. /evidence=ECO:0000269|PubMed:25995448, ECO:0007744|PDB:4ZET 184..186 40/173 (23%)
Carbohydrate binding. /evidence=ECO:0000269|PubMed:25995448, ECO:0007744|PDB:4ZET 194..195
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR22802
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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