Protein Alignment Gsc and MIXL1

DIOPT Version :10

• Sequence 1: NP_001137762.2
• Gene: Gsc / 33240
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_001269331.1
• Gene: MIXL1 / 83881
• HGNCID: 13363
• Length: 240
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 59/208 - (28%)
• Similarity: 81/208 - (38%)
• Gaps: 57/208 - (27%)

  Fly   284 AAAQMQAHVSGAA----AGLSGHGHHPHHPH----GHPHHPHLGAHHHGQHHLSHLGHGPPPKRK 340
            |||.:.|..:|..    ||..|....|..|.    |.|..|.              |...|...:
Human    36 AAALLPAPPAGPGPATFAGFLGRDPGPAPPPPASLGSPAPPK--------------GAAAPSASQ 86

  Fly   341 RRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERV--------EVWFKNRRAKWRK 397
            ||.||.|:.|||:.||..|.:|.|||:.|||:||....|.|.|:        :|||:|||||.|:
Human    87 RRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQLLFSPLFQVWFQNRRAKSRR 151

  Fly   398 QKREEQERLRKLQ-----------------------EEQCGSTTNGTTNSSSGTTSSTGNGSLTV 439
            |..:..:.|.:.:                       :..|....||.   ..|.:.|:..|....
Human   152 QSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVDVNCLPEPNGV---GGGISDSSSQGQNFE 213

  Fly   440 KC-PGSDHYSAQL 451
            .| |.|:...::|
Human   214 TCSPLSEDIGSKL 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeodomain	341..397	CDD:459649	31/63 (49%)
MIXL1	NP_001269331.1	Homeodomain	87..151	CDD:459649	31/63 (49%)