DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Gsc and pitx1

DIOPT Version :9

Sequence 1:NP_001137762.2 Gene:Gsc / 33240 FlyBaseID:FBgn0010323 Length:473 Species:Drosophila melanogaster
Sequence 2:NP_001035436.3 Gene:pitx1 / 678598 ZFINID:ZDB-GENE-060421-3623 Length:285 Species:Danio rerio


Alignment Length:79 Identity:43/79 - (54%)
Similarity:57/79 - (72%) Gaps:2/79 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly   332 GHGPPPKRK--RRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAK 394
            |:...||:|  ||.||.||.:||::|||||.:..|||:..||::|:..:|.|.||.|||||||||
Zfish    48 GNADDPKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 112

  Fly   395 WRKQKREEQERLRK 408
            |||::|.:|..|.|
Zfish   113 WRKRERNQQMDLCK 126

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GscNP_001137762.2 Homeobox 343..396 CDD:278475 30/52 (58%)
pitx1NP_001035436.3 COG5576 8..>126 CDD:227863 42/77 (55%)
Homeobox 62..114 CDD:278475 30/51 (59%)
OAR 247..263 CDD:281777
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R6207
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.940

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