DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gsc and dmbx1b

DIOPT Version :9

Sequence 1:	NP_001137762.2	Gene:	Gsc / 33240	FlyBaseID:	FBgn0010323	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_001017625.1	Gene:	dmbx1b / 550288	ZFINID:	ZDB-GENE-050417-97	Length:	369	Species:	Danio rerio

Alignment Length:	212	Identity:	68/212 - (32%)
Similarity:	103/212 - (48%)	Gaps:	52/212 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 GLSGHGHHPHHPHGHPHHPHLGAHHHGQH--------HLSHLG-----------HGPPPKRKRRH 343
            |::|:..|..:.....::.|..|..|.||        |...|.           :|...:::||.
Zfish     5 GVNGYSLHAMNSLSAMYNLHQQAAQHAQHAPDYRPSVHALTLAERLADIILEARYGSQHRKQRRS 69

  Fly   344 RTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKRE-EQERLR 407
            ||.||.:|||.||.||.||||||||:||:||:..:|.|.||:|||||||||:||::|. ::|:|:
Zfish    70 RTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQ 134

  Fly   408 KLQEEQCGSTTNGTTNSSSGTTSSTGNGS-----LTVKCP-----GSDHYSAQLVHIKSDPN--- 459
            :|:|              :||..:...|.     :..:.|     |....||....:..:.|
Zfish   135 RLKE--------------AGTEGAQDEGKEEAPPVEAQAPPSPLDGRGLTSAPSCELNEEVNVTS 185

  Fly   460 -----GYSDADESSDLE 471
                 ..|.|::::|.|
Zfish   186 PEQSGAESGAEDTTDRE 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeobox	343..396	CDD:278475	36/52 (69%)
dmbx1b	NP_001017625.1	Homeobox	69..122	CDD:278475	36/52 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	124..253		17/93 (18%)
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	346..359
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	1	1.000	-	-		X6207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940