DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gsc and Pdlim1

DIOPT Version :9

Sequence 1:	NP_001137762.2	Gene:	Gsc / 33240	FlyBaseID:	FBgn0010323	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_058557.2	Gene:	Pdlim1 / 54132	MGIID:	1860611	Length:	327	Species:	Mus musculus

Alignment Length:	196	Identity:	36/196 - (18%)
Similarity:	55/196 - (28%)	Gaps:	63/196 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GGGGTTTTTPSTTPDIPPSK------------------AKFKITVVSTPSPS-------PPPTPP 50
            |.....:..|.|....|.::                  :.|...|.|..|.|       |...|.
Mouse   117 GSAHNRSAMPFTASPAPSTRVITNQYNSPTGLYSSENISNFNNAVESKTSASGEEANSRPVVQPH 181

  Fly    51 PAGS-----------MLAQMVETNSPPAGYTL---------------KRSPSDLGEQQQPPRQIS 89
            |:||           ||.:..|.|.||...|.               ...||.....:.|..:::
Mouse   182 PSGSLIIDKDSEVYKMLQEKQELNEPPKQSTSFLVLQEILESDGKGDPNKPSGFRSVKAPVTKVA 246

  Fly    90 RSPGNTAAYHLTTAMLLNSQQCGYLGQRLQSVL--QQQHAQHQQSQSQTPSSDDGSQSGVTILEE 152
            .|.||.....:          |...|..:..|.  .:.|.:|.:....|....:..|.|...:|:
Mouse   247 ASVGNAQKLPI----------CDKCGTGIVGVFVKLRDHHRHPECYVCTDCGINLKQKGHFFVED 301

  Fly   153 E 153
            :
Mouse   302 Q 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeobox	343..396	CDD:278475
Pdlim1	NP_058557.2	PDZ_signaling	5..81	CDD:238492
		DUF4749	136..228	CDD:292558	17/91 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..184		7/22 (32%)
		LIM_CLP36	258..309	CDD:188832	9/45 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030