Protein Alignment Gsc and ey

DIOPT Version :10

• Sequence 1: NP_001137762.2
• Gene: Gsc / 33240
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Alignment Length: 611
• Identity: 135/611 - (22%)
• Similarity: 212/611 - (34%)
• Gaps: 164/611 - (26%)

  Fly     2 LSSLWTPGGGGGGTTTTTPSTTPDI--------PPSKAKFKITV---------------VSTPSP 43
            |..|.|.||.|.|.....||.|.:.        |.|.:.:..|.               :.....
  Fly    45 LPCLGTAGGSGLGGIAGKPSPTMEAVEASTASHPHSTSSYFATTYYHLTDDECHSGVNQLGGVFV 109

  Fly    44 SPPPTPPPAGSMLAQMVETNSPPAGYTLKRSPSD------LGEQQQP----PRQISRSPGNTAAY 98
            ...|.|......:.::..:.:.|...:.....|:      ||...:.    ||.|..|....|..
  Fly   110 GGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATA 174

  Fly    99 HLTTAMLLNSQQCGYL------GQRLQS----------------VLQQQHAQHQQSQSQTPSSDD 141
            .:.:.:....::|..:      .:.||.                ||:...||.:|..:.:.||..
  Fly   175 EVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQKEQQSTGSGSSST 239

  Fly   142 GSQSGVTILEEERRGG----AAAASLFTIDSI---------LGSRQQGGGTAPSQGSHISSNGNQ 193
            .:.:.::.......||    .|:.|..|:.|.         |.|.:.||.:...:||      .|
  Fly   240 SAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGEGS------EQ 298

  Fly   194 NGLTSNGISLGLKRSGAESPASPNSNSSSSAAASPI---RPQRVPAMLQHPGL-HLGHLAAAAAS 254
            ..:......|..:.:....|..|       |.|:|:   .|..:.....||.| |..|.|.....
  Fly   299 EAIYEKLRLLNTQHAAGPGPLEP-------ARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQ 356

  Fly   255 GFAASPSDFLVAYPNFYPNYMHAAAVAHVA-AAQMQAHVSGAA-----------AGLSGHGHHPH 307
            ..:..|..:   ..::||..:....::... .|.:.|:.||.:           ..|:..||..:
  Fly   357 QQSWPPRHY---SGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRN 418

  Fly   308 HP------------HGH-PHHPHLGAHHHGQHHLSHLGHGPPP------KRK-RRHRTIFTEEQL 352
            .|            .|| ......|...:.....|::|:....      ||| :|:||.||.:|:
  Fly   419 CPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQI 483

  Fly   353 EQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKREEQERLRKLQEEQCGST 417
            :.||..|::||||||..||:||.|:.|.|.|::|||.|||||||:     :|:||..:.....:.
  Fly   484 DSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRR-----EEKLRNQRRTPNSTG 543

  Fly   418 TNGTTNSSSGTTS------------------------STGNG-------SLTVKCP------GSD 445
            .:.|::|:|.|.|                        ||.||       |..|..|      .|.
  Fly   544 ASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSS 608

  Fly   446 HYSAQLVHIKSDPNGYSDADESSDLE 471
            .....:.||:  |:..||.|.....|
  Fly   609 ESPTPIPHIR--PSCTSDNDNGRQSE 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeodomain	341..397	CDD:459649	32/55 (58%)
ey	NP_001014693.1	PAX	98..221	CDD:128645	15/122 (12%)
		Homeodomain	473..528	CDD:459649	32/54 (59%)