Protein Alignment Gsc and ap

DIOPT Version :10

• Sequence 1: NP_001137762.2
• Gene: Gsc / 33240
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_724428.1
• Gene: ap / 35509
• FlyBaseID: FBgn0267978
• Length: 469
• Species: Drosophila melanogaster
• Alignment Length: 463
• Identity: 98/463 - (21%)
• Similarity: 147/463 - (31%)
• Gaps: 173/463 - (37%)

  Fly     8 PGGGGGGTTTTTPSTTPD---IPPSKAKFKI-------TVVSTPSPSPPPTPPPAGSMLAQMVET 62
            |.|...||.:.....|.|   ...|.|||.|       |.||.                    ||
  Fly    72 PFGNAYGTESFRSYETADRATFEDSAAKFSISRSRTDCTEVSD--------------------ET 116

  Fly    63 NSPPAGYTLKRSPSDLGEQQQPPRQISRSPGNTAAYHLTTAMLLNSQQCGYLGQRLQ------SV 121
            .|   |.:.|..|..      ||    .||.:|:...:|.    |...|...|:::|      :|
  Fly   117 TS---GISFKTEPFG------PP----SSPESTSDSKITR----NLDDCSGCGRQIQDRFYLSAV 164

  Fly   122 LQQQHAQHQQ----SQSQTPSSDDGSQSGVTILEEE-------RRGGAAAASLFTIDSILGSRQQ 175
            .::.||...|    .|.....|...|:.|....:.:       ||.....||:.:.:.::.:|
  Fly   165 EKRWHASCLQCYACRQPLERESSCYSRDGNIYCKNDYYSFFGTRRCSRCLASISSNELVMRAR-- 227

  Fly   176 GGGTAPSQGSHIS-----------SNGNQNGLTSNGI----SLGLKRSGAESPASPNS------- 218
                  :...|::           :.|:|.|:....|    ...:.|.|..:.:|.::
  Fly   228 ------NLVFHVNCFCCTVCHTPLTKGDQYGIIDALIYCRTHYSIAREGDTASSSMSATYPYSAQ 286

  Fly   219 -----NSSSSAAASPIRPQRVPAMLQHPGLHL--GHLAAAAASG------------FAASPSDFL 264
                 |.|||..:.|.| ..||..:..|..|:  |....|...|            |.|: .|..
  Fly   287 FGSPHNDSSSPHSDPSR-SIVPTGIFVPASHVINGLPQPARQKGRPRKRKPKDIEAFTAN-IDLN 349

  Fly   265 VAYPNFYPNYMHAAAVAHVAAAQMQAHVSGAAAGLSGHGHHPHHPHGHPHHPHLGAHHHGQHHLS 329
            ..|.:|                              |.|                         |
  Fly   350 TEYVDF------------------------------GRG-------------------------S 359

  Fly   330 HLGHGPPPKRKRRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAK 394
            ||...   .|.:|.||.|...||..:::.|...|.||....:||:.|..|.:..::|||:|.|||
  Fly   360 HLSSS---SRTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLSQKTGLPKRVLQVWFQNARAK 421

  Fly   395 WRKQKREE 402
            ||:...::
  Fly   422 WRRMMMKQ 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeodomain	341..397	CDD:459649	22/55 (40%)
ap	NP_724428.1	LIM1_Lhx2_Lhx9	148..201	CDD:188755	11/52 (21%)
		LIM2_Lhx2_Lhx9	206..264	CDD:188763	10/65 (15%)
		Homeodomain	368..424	CDD:459649	22/55 (40%)