Protein Alignment Gsc and HOXB8

DIOPT Version :9

• Sequence 1: NP_001137762.2
• Gene: Gsc / 33240
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 64/274 - (23%)
• Similarity: 97/274 - (35%)
• Gaps: 70/274 - (25%)

  Fly   162 SLFTIDSILGSRQQGGGTAPSQGSHISSNGNQNGLTSNGISLGLKRSGAESPASPNS-------- 218
            |.:.::|:....:.|....|        |....|...:   ||.:.:....|:|..|
Human     2 SSYFVNSLFSKYKTGESLRP--------NYYDCGFAQD---LGGRPTVVYGPSSGGSFQHPSQIQ 55

  Fly   219 ---NSSSSAAASPIRPQRVPAMLQH--PGLHLGHLAAAAASGFAASPSDFLVAYPNFYPNYMHAA 278
               :..||.:.:|.: |...|:..|  ||...|:......|.|.|...| ||.|
Human    56 EFYHGPSSLSTAPYQ-QNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPD-LVQY----------- 107

  Fly   279 AVAHVAAAQMQAHVSGAAAGLSGHGHHPHHPHGHP-HHPHLGAHHHGQHHLSHLGHGPPPKRKRR 342
            |...:|||      ||......|....|......| ..|...|                  .:||
Human   108 ADCKLAAA------SGLGEEAEGSEQSPSPTQLFPWMRPQAAA------------------GRRR 148

  Fly   343 HRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKRE------ 401
            .|..::..|..:||..|....|.....|.:::..:.|.|.:|::||:|||.||:|:..:
Human   149 GRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSS 213

  Fly   402 --EQERLRKLQEEQ 413
              |||.|.|.:.|:
Human   214 KCEQEELEKQKLER 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeobox	343..396	CDD:278475	16/52 (31%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		1/4 (25%)
		Homeobox	150..203	CDD:395001	17/52 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		7/25 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030