Protein Alignment Gsc and Alx4

DIOPT Version :10

• Sequence 1: NP_001137762.2
• Gene: Gsc / 33240
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_001100023.1
• Gene: Alx4 / 296511
• RGDID: 1310201
• Length: 399
• Species: Rattus norvegicus
• Alignment Length: 301
• Identity: 84/301 - (27%)
• Similarity: 117/301 - (38%)
• Gaps: 95/301 - (31%)

  Fly   132 SQSQTPSS-----DDGSQSGVTILEEERRGGAAAASLFTIDSILGSRQQGGGTAPSQGSHISSNG 191
            |||:..||     ..|.:.|.|.|....:|                  ||.|.|..:..:
  Rat    25 SQSREGSSPFRGFPGGDKFGTTFLSAAAKG------------------QGFGDAKGRARY----- 66

  Fly   192 NQNGLTSNGISLGLKRSGAESPASP-NSNSSSSAAASPIRPQ----RVPAMLQHPGLHLGHLAAA 251
                           .:|.:..|:| .||:.:..:.:..:||    :.|.....|..|| :|...
  Rat    67 ---------------GAGQQDLAAPLESNAGARGSFNKFQPQPPTPQPPPAPPAPPAHL-YLQRG 115

  Fly   252 AASGFAASPSDFLVAYPNFYPNYMHAAAVAHVAAAQMQAHVSGAAAGLSGHGHHPHHPHGHP--- 313
            |..    :|.|..:.        :...:..|.||.|:..:     |..|..|.....|...|
  Rat   116 ACK----TPPDGSLK--------LQEGSGGHNAALQVPCY-----AKESNLGEPELPPDSEPVGM 163

  Fly   314 HHPHLGAHHHGQHHLSHLGHGPPPK-------------------RKRRHRTIFTEEQLEQLEATF 359
            .:.:|.....|       ..||..:                   :|||:||.||..|||:||..|
  Rat   164 DNSYLSVKETG-------AKGPQDRAGAEIPSPLEKTDSESSKGKKRRNRTTFTSYQLEELEKVF 221

  Fly   360 DKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKR 400
            .|||||||..|||||::.||.|.||:|||:||||||||::|
  Rat   222 QKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRER 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeodomain	341..397	CDD:459649	38/55 (69%)
Alx4	NP_001100023.1	Homeodomain	203..259	CDD:459649	38/55 (69%)
		OAR	375..393	CDD:461067