Protein Alignment Gsc and Alx1

DIOPT Version :10

• Sequence 1: NP_001137762.2
• Gene: Gsc / 33240
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_037053.1
• Gene: Alx1 / 25401
• RGDID: 2273
• Length: 326
• Species: Rattus norvegicus
• Alignment Length: 163
• Identity: 62/163 - (38%)
• Similarity: 78/163 - (47%)
• Gaps: 40/163 - (24%)

  Fly   311 GHPHHPHLGAHHHGQHHLSHLG-HGPPPK-----------------RKRRHRTIFTEEQLEQLEA 357
            |.|.|..|.....|.::|.... .|.|.|                 :||||||.||..|||:||.
  Rat    85 GQPLHTELNRAMDGCNNLRMSPVKGMPEKSELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEK 149

  Fly   358 TFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKREEQERLRKLQE----------- 411
            .|.|||||||.:||||||:.:|.|.||:|||:||||||||     :||..::|:
  Rat   150 VFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRK-----RERYGQIQQAKSHFAATYDI 209

  Fly   412 ---EQCGSTTNGTTNSSSGTTSSTGNGSLTVKC 441
               .:..|......|..:|.||   .||:...|
  Rat   210 SVLPRTDSYPQIQNNLWAGNTS---GGSVVTSC 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeodomain	341..397	CDD:459649	39/55 (71%)
Alx1	NP_037053.1	Homeodomain	133..189	CDD:459649	39/55 (71%)
		Transactivation domain. /evidence=ECO:0000269|PubMed:12390248	192..326		10/51 (20%)
		OAR	302..320	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	306..319