Protein Alignment Gsc and Gsc2

DIOPT Version :10

• Sequence 1: NP_001137762.2
• Gene: Gsc / 33240
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_083745.2
• Gene: Gsc2 / 195333
• MGIID: 892006
• Length: 201
• Species: Mus musculus
• Alignment Length: 269
• Identity: 82/269 - (30%)
• Similarity: 101/269 - (37%)
• Gaps: 104/269 - (38%)

  Fly   164 FTIDSILGS----------RQQGGGTAPSQGSHISSNGNQNGLTSNGISLGLKRSGAESPASPNS 218
            |:|:.||.|          .|..||..|::                     |....|..||:|
Mouse    19 FSIEHILSSLPERRPATRPPQPVGGRNPAE---------------------LDEPEAPVPAAP-- 60

  Fly   219 NSSSSAAASPIRPQR-VPAMLQHPGLHLG---HLAAAAASGFAASPSDFLVAYPNFYPNYMHAAA 279
             .:.....:|....| .|.....|||.|.   .||.|..|...|..:.
Mouse    61 -CACCCCCNPRAATRGTPETSSGPGLRLAWPLRLAPATPSPLTAPRAG----------------- 107

  Fly   280 VAHVAAAQMQAHVSGAAAGLSGHGHHPHHPHGHPHHPHLGAHHHGQHHLSHLGHGPPPKRKRRHR 344
                         |.|..|.||.|                                |.:|.||||
Mouse   108 -------------SPALTGTSGPG--------------------------------PQRRTRRHR 127

  Fly   345 TIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKREEQERL--- 406
            |||:||||:.|||.|.:..||||..||:||:::.|:||||||||||||||||.|||....||
Mouse   128 TIFSEEQLQALEALFVQNQYPDVGTRERLAVRIRLREERVEVWFKNRRAKWRHQKRASSSRLLPG 192

  Fly   407 -RKLQEEQC 414
             :|..:|.|
Mouse   193 TKKTPKESC 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeodomain	341..397	CDD:459649	39/55 (71%)
Gsc2	NP_083745.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55		10/56 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..124		11/90 (12%)
		Homeodomain	124..180	CDD:459649	39/55 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..201		8/21 (38%)