DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gsc and Pitx3

DIOPT Version :9

Sequence 1:	NP_001137762.2	Gene:	Gsc / 33240	FlyBaseID:	FBgn0010323	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	XP_006526827.1	Gene:	Pitx3 / 18742	MGIID:	1100498	Length:	388	Species:	Mus musculus

Alignment Length:	217	Identity:	72/217 - (33%)
Similarity:	91/217 - (41%)	Gaps:	57/217 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 ISLGLKRSGAESPAS---PNSNSSSSAAASPIRPQRVPAMLQHPGLHLGHLAAAAASGFAASPSD 262
            :|||.....:....|   |.....|:.....|:.||.|:|      ..|.|..|.|...|.|.||
Mouse    48 LSLGAHSLNSACHCSGCYPLPGPPSTEIEDEIKRQRPPSM------EFGLLGEAEARSPALSLSD 106

  Fly   263 FLVAYPNFYPNYMHAAAVAHVAAAQMQAHVSGAAAGLSGHGHHPHHPHGHPHHPHLGAHHHGQHH 327
                                              ||.      ||.|  .|.|...|..|.....
Mouse   107 ----------------------------------AGT------PHPP--LPEHGCKGQEHSDSEK 129

  Fly   328 LS-HLGHGPP-----PKRKRRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEV 386
            .| .|..|.|     .|::||.||.||.:||::|||||.:..|||:..||::|:..:|.|.||.|
Mouse   130 ASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRV 194

  Fly   387 WFKNRRAKWRKQKREEQERLRK 408
            |||||||||||::|.:|..|.|
Mouse   195 WFKNRRAKWRKRERSQQAELCK 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeobox	343..396	CDD:278475	30/52 (58%)
Pitx3	XP_006526827.1	Homeobox	152..205	CDD:365835	31/52 (60%)
		PTZ00395	<228..>322	CDD:185594
		OAR	344..361	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940