Protein Alignment Gsc and Pax3

DIOPT Version :10

• Sequence 1: NP_001137762.2
• Gene: Gsc / 33240
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_001152992.1
• Gene: Pax3 / 18505
• MGIID: 97487
• Length: 484
• Species: Mus musculus
• Alignment Length: 148
• Identity: 58/148 - (39%)
• Similarity: 73/148 - (49%)
• Gaps: 24/148 - (16%)

  Fly   336 PPKRK-RRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQK 399
            |.||| ||.||.||.||||:||..|::|||||:..||:||.:..|.|.||:|||.||||:||||.
Mouse   214 PLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQA 278

  Fly   400 REEQ--------------ERLRKLQEEQCGSTTNGTTNSSSGTTSSTGNGSLTVKCPGSDHYSAQ 450
            ...|              ..:..|...|...|:...|:    ...:..:.|.||..|  ......
Mouse   279 GANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTS----IPQAVSDPSSTVHRP--QPLPPS 337

  Fly   451 LVHIKSDPNGYSDADESS 468
            .||..:.|   |:||.||
Mouse   338 TVHQSTIP---SNADSSS 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeodomain	341..397	CDD:459649	34/55 (62%)
Pax3	NP_001152992.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		PAX	34..159	CDD:128645
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	37..93
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	113..161
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..228		9/13 (69%)
		Homeodomain	220..276	CDD:459649	34/55 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..351		12/50 (24%)
		Pax7	347..391	CDD:403540	4/6 (67%)