DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gsc and vab-3

DIOPT Version :9

Sequence 1:	NP_001137762.2	Gene:	Gsc / 33240	FlyBaseID:	FBgn0010323	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_001024570.1	Gene:	vab-3 / 181251	WormBaseID:	WBGene00006870	Length:	455	Species:	Caenorhabditis elegans

Alignment Length:	155	Identity:	57/155 - (36%)
Similarity:	79/155 - (50%)	Gaps:	31/155 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   338 KRK-RRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKRE 401
            ||| :|:||.||:.|:|.||..|::||||||..||:||.|:.|.|.|::|||.|||||||   ||
Worm   214 KRKLQRNRTSFTQVQIESLEKEFERTHYPDVFARERLAQKIQLPEARIQVWFSNRRAKWR---RE 275

  Fly   402 EQERLRKLQEEQCGSTTNGTTNSSSGT---------------------TSSTGNGSLTVKCPGSD 445
            |:.|.::.......|.:|||...:.|:                     ::::.|...|...|.:.
Worm   276 EKMRNKRSSGTMDSSLSNGTPTPTPGSVTGSNMTNPIGSPASTPNRFPSNNSANLPTTNFVPQTS 340

  Fly   446 HYSAQLVHIKSDP------NGYSDA 464
            ...|.|.....||      ||:|.|
Worm   341 QMYAGLSQPAMDPYSFGIANGFSMA 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeobox	343..396	CDD:278475	31/52 (60%)
vab-3	NP_001024570.1	PAX	5..129	CDD:128645
		COG5576	183..293	CDD:227863	42/81 (52%)
		Homeobox	221..274	CDD:395001	33/55 (60%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940