DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gsc and dmbx1a

DIOPT Version :9

Sequence 1:	NP_001137762.2	Gene:	Gsc / 33240	FlyBaseID:	FBgn0010323	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_694509.1	Gene:	dmbx1a / 142987	ZFINID:	ZDB-GENE-020117-1	Length:	388	Species:	Danio rerio

Alignment Length:	218	Identity:	69/218 - (31%)
Similarity:	108/218 - (49%)	Gaps:	49/218 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 GLSGHGHHPHHPHGHPHHPHLGAHHHGQH--------HLSHLG----------------HGPPPK 338
            |::|:..|..:.....::.|..|....||        |...|.                :|...:
Zfish     5 GVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHR 69

  Fly   339 RKRRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKRE-E 402
            ::||.||.||.:|||.||.||.||||||||:||:||:..:|.|.||:|||||||||:||::|. :
Zfish    70 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQ 134

  Fly   403 QERLRKLQE------------EQCGSTTNGTTNSSSGTTSSTGNGSLTVKCPGSDH-----YSAQ 450
            :|:|:|.::            ::..||.|......|.|:||:     :::...:.|     .|.:
Zfish   135 KEQLQKQKDVSTDGALAASDKDEAPSTLNLENQPPSSTSSSS-----SMEAEAAPHALGSELSVE 194

  Fly   451 LVHIKSDPNGYSDA--DESSDLE 471
            |....::.:|...|  |.::|.|
Zfish   195 LNVTSAEQSGSESATEDNATDKE 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gsc	NP_001137762.2	Homeobox	343..396	CDD:278475	36/52 (69%)
dmbx1a	NP_694509.1	Homeobox	74..127	CDD:278475	36/52 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	129..272		19/94 (20%)
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	365..378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	1	1.000	-	-		X6207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940