Protein Alignment Pph13 and DRGX

DIOPT Version :10

• Sequence 1: NP_477330.1
• Gene: Pph13 / 33239
• FlyBaseID: FBgn0023489
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: XP_011538391.1
• Gene: DRGX / 644168
• HGNCID: 21536
• Length: 298
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 87/297 - (29%)
• Similarity: 111/297 - (37%)
• Gaps: 111/297 - (37%)

  Fly     2 DKGTMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQ----------- 55
            |.|.::|||||.||||...||:.||..|.:|||||||.|||||::|:|||||||
Human    25 DDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQLANSCLKTELQ 89

  Fly    56 ------------------------VWFQNRRAKWRKQEKIGGLGGDYKEGALDLDVSYDDSAVLG 96
                                    ||||||||||||.|:                         |
Human    90 IEINDTIIEHSEVEDHNFSLKGARVWFQNRRAKWRKTER-------------------------G 129

  Fly    97 QLDSALGGGGTLLPDTPPQSSN-----------SLDNELKA--SYG-----TGAMSPSRLSPNIF 143
            ..|...|....:...|||...|           |....|:|  |.|     .|...||.| |...
Human   130 ASDQEPGAKEPMAEVTPPPVRNINSPPPGDQARSKKEALEAQQSLGRTVGPAGPFFPSCL-PGTL 193

  Fly   144 LNL-----NIDHLGLERGG----------SGLSMEWSTYPPQT-----------QAQTHPQ--MD 180
            ||.     .:.|:...:||          .|||. ..||..|:           :|:.|.:  :.
Human   194 LNTATYAQALSHVASLKGGPLCSCCVPDPMGLSF-LPTYGCQSNRTASVATLRMKAREHSEAVLQ 257

  Fly   181 SDNQLQQHPPQQHASDPIHAGSSSHHQQQQQQHQQEQ 217
            |.|.|   |....:..|:...:.....|::....:||
Human   258 SANLL---PSTSSSPGPVAKPAPPDGSQEKTSPTKEQ 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeodomain	11..67	CDD:459649	41/90 (46%)
DRGX	XP_011538391.1	Homeodomain	34..125	CDD:459649	41/90 (46%)
		OAR	236..253	CDD:461067	2/16 (13%)