Protein Alignment Pph13 and PROP1

DIOPT Version :10

• Sequence 1: NP_477330.1
• Gene: Pph13 / 33239
• FlyBaseID: FBgn0023489
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_006252.4
• Gene: PROP1 / 5626
• HGNCID: 9455
• Length: 226
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 61/217 - (28%)
• Similarity: 80/217 - (36%)
• Gaps: 87/217 - (40%)

  Fly    10 QRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQEKIGGL 74
            :||:||||:.:||::||.||.|..|||::.||.||....|:|||:||||||||||.||||:
Human    69 RRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQER---- 129

  Fly    75 GGDYKEGALDLDVSYDDSAVLGQLDSALGGGGTLLPDTPPQSSNSLDNELKASYGTGAMSPSRLS 139
                                                        ||...|           :.||
Human   130 --------------------------------------------SLLQPL-----------AHLS 139

  Fly   140 PNIFLNLNIDHLGLERGGSGLSMEWSTYPPQTQAQTHPQMDSDNQLQQHPPQQHA--SDPIHAGS 202
            |..|.:...:       .:.....::..||......|             |..||  |.|...|:
Human   140 PAAFSSFLPE-------STACPYSYAAPPPPVTCFPH-------------PYSHALPSQPSTGGA 184

  Fly   203 SSHHQQQQQQHQQEQHNPQLHP 224
            .:      ..||.|...|.|||
Human   185 FA------LSHQSEDWYPTLHP 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeodomain	11..67	CDD:459649	34/55 (62%)
PROP1	NP_006252.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..75		3/5 (60%)
		Homeodomain	70..126	CDD:459649	34/55 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	196..226		4/5 (80%)